Reference on EC 2.8.2.8 - [heparan sulfate]-glucosamine N-sulfotransferase and Organism(s) Homo sapiens and UniProt Accession O95803
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Sueyoshi, T.; Kakuta, Y.; Pedersen, L.C.; Wall, F.E.; Pedersen, L.G.; Negishi, M.
A role of Lys614 in the sulfotransferase activity of human heparan sulfate N-deacetylase/N-sulfotransferase
FEBS Lett.
433
211-214
1998
Homo sapiens
Kakuta, Y.; Sueyoshi, T.; Negishi, M.; Pedersen, L.C.
Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/N-sulfotransferase 1
J. Biol. Chem.
274
10673-10676
1999
Homo sapiens
Aikawa, J.; Esko, J.D.
Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/N-sulfotransferase family
J. Biol. Chem.
274
2690-2695
1999
Cricetulus griseus, Homo sapiens (O95803), Homo sapiens
Gorokhov, A.; Perera, L.; Darden, T.A.; Negishi, M.; Pedersen, L.C.; Pedersen, L.G.
Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase
Biophys. J.
79
2909-2917
2000
Homo sapiens
Aikawa, J.; Grobe, K.; Tsujimoto, M.; Esko, J.D.
Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4
J. Biol. Chem.
276
5876-5882
2001
Homo sapiens (O95803), Homo sapiens (Q9H3R1), Homo sapiens, Mus musculus (P52850), Mus musculus (Q3UHN9), Mus musculus (Q9EQH7), Mus musculus (Q9EQW8), Mus musculus
Grobe, K.; Ledin, J.; Ringvall, M.; Holmborn, K.; Forsberg, E.; Esko, J.D.; Kjellen, L.
Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes
Biochim. Biophys. Acta
1573
209-215
2002
Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Homo sapiens (O95803), Homo sapiens (Q9H3R1), Mus musculus, Mus musculus (Q9EQW8), vertebrata
Duncan, M.B.; Liu, M.; Fox, C.; Liu, J.
Characterization of the N-deacetylase domain from the heparan sulfate N-deacetylase/N-sulfotransferase 2
Biochem. Biophys. Res. Commun.
339
1232-1237
2006
Homo sapiens
Deligny, A.; Denys, A.; Marcant, A.; Melchior, A.; Mazurier, J.; van Kuppevelt, T.H.; Allain, F.
Synthesis of heparan sulfate with cyclophilin B-binding properties is determined by cell type-specific expression of sulfotransferases
J. Biol. Chem.
285
1701-1715
2010
Homo sapiens
Dou, W.; Xu, Y.; Pagadala, V.; Pedersen, L.C.; Liu, J.
Role of deacetylase activity of N-deacetylase/n-sulfotransferase 1 in forming n-sulfated domain in heparan sulfate
J. Biol. Chem.
290
20427-20437
2015
Homo sapiens (P52848)
Kero, D.; Bilandzija, T.; Arapovic, L.; Vukojevic, K.; Saraga-Babic, M.
Syndecans and enzymes involved in heparan sulfate biosynthesis and degradation are differentially expressed during human dontogenesis
Front. Physiol.
9
732
2018
Homo sapiens (P52848), Homo sapiens (P52849), Homo sapiens
Ushakov, V.; Tsidulko, A.; De La Bourdonnaye, G.; Kazanskaya, G.; Volkov, A.; Kiselev, R.; Kobozev, V.; Kostromskaya, D.; Gaytan, A.; Krivoshapkin, A.; Aidagulova, S.; Grigorieva, E.
Heparan sulfate biosynthetic system is inhibited in human glioma due to EXT1/2 and HS6ST1/2 down-regulation
Int. J. Mol. Sci.
18
2301
2017
Homo sapiens (P52848), Homo sapiens (P52849)
Li, Y.J.; Yin, F.X.; Zhang, X.K.; Yu, J.; Zheng, S.; Song, X.L.; Wang, F.S.; Sheng, J.Z.
Characterization of heparan sulfate N-deacetylase/N-sulfotransferase isoform 4 using synthetic oligosaccharide substrates
Biochim. Biophys. Acta
1862
547-556
2018
Homo sapiens (P52848), Homo sapiens (Q9H3R1), Homo sapiens
Zhang, X.; Wang, F.; Sheng, J.
''Coding'' and ''Decoding'' hypothesis for the regulatory mechanism involved in heparan sulfate biosynthesis
Carbohydr. Res.
428
1-7
2016
Homo sapiens (O95803), Homo sapiens (P52848), Homo sapiens (P52849), Homo sapiens (Q9H3R1)