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3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
3'-phosphoadenylyl sulfate + N-acetyllactosamine
adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine
-
-
-
-
?
3'-phosphoadenylylsulfate + agarose
adenosine 3',5'-bisphosphate + ?
-
sulfotransferase I active, sulfotransferase II not
-
-
?
3'-phosphoadenylylsulfate + chitin dodecylsaccharide
adenosine 3',5'-bisphosphate + ?
-
sulfotransferase I and II
-
-
?
3'-phosphoadenylylsulfate + fetuin
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + GlcNAcbeta1-3Galbeta1-4GlcNACbeta1-3Galbeta1-4GlcNAcbeta1-6Manalpha1-6Manbeta-octyl
adenosine 3',5'-bisphosphate + ?
-
synthetic substrate, sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase
-
-
?
3'-phosphoadenylylsulfate + GlyCAM-1
adenosine 3',5'-bisphosphate + ?
-
endothelial mucin-like ligand for L-selectin, products correspond to [SO3-6]GlcNAc and Galbeta1-4[SO3-6]GlcNAc
-
-
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1(6-sulfo)GlcNAcbeta1-3(6-sulfo)Galbeta1-4(6-sulfo)GlcNAc
adenosine 3',5'-bisphosphate + NeuAcalpha2-3-(6-sulfo)Galbeta1-(6-sulfo)GlcNAcbeta1-3(6-sulfo)Galbeta1-4(6-sulfo)GlcNAc
-
sulfation at position 6 of Gal residues
-
-
?
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1-4GlcNAc
adenosine 3',5'-bisphosphate + NeuAcalpha2-3(6-sulfo)Galbeta1-4GlcNAc
-
sulfation at position 6 of Gal residues, no sulfation of GlcNAc
-
-
?
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1-4GlcNAcbeta1-3Galbeta1-4GlcNAc
adenosine 3',5'-bisphosphate + ?
-
sulfation at position 6 of Gal residues
-
-
?
3'-phosphoadenylylsulfate + pyridylamino-GlcNAcbeta1-3Galbeta1-4GlcNAc
adenosine 3',5'-bisphosphate + pyridylamino-GlcNAcbeta1-3Galbeta1-4(6-sulfo)GlcNAc
-
sulfation at GlcNAc residues at the nonreducing end but no sulfation of internal GlcNAc
-
-
?
additional information
?
-
3'-phosphoadenylyl sulfate + keratan

adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
keratan sulfate proteoglycan is expressed in the extracellular matrix or cell surface in numerous tissues, predominantly in those of the cornea, cartilage, and brain
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
pericellular localization of R-10G reactive KS epitopes in perineuronal net-positive neurons in the visual cortex of adult mice
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
pericellular localization of R-10G reactive KS epitopes in perineuronal net-positive neurons in the visual cortex of adult mice
-
-
?
3'-phosphoadenylylsulfate + keratan sulfate

adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
both enzyme species react best with keratan sulfate segments exhibiting a relatively high degree of sulfation
specificity, sulfotransferase I: 60% of the sulfate ester groups formed are linked to the C-6 atom of galactosyl residues, the rest to the C-6 atom of N-acetylglucosamine, sulfotransferase II: 23% of the newly formed sulfate ester groups are on galactosyl and 77% on N-acetylglucosaminyl residues
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
activity decreases with increasing molecular mass and sulfation degree of keratan sulfate
-
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
no activity with keratansulfate-derived oligosaccharides
specificity, sulfotransferase I: 60% of the sulfate ester groups formed are linked to the C-6 atom of galactosyl residues, the rest to the C-6 atom of N-acetylglucosamine, sulfotransferase II: 23% of the newly formed sulfate ester groups are on galactosyl and 77% on N-acetylglucosaminyl residues
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
very weak activity towards desulfated keratan sulfate
specificity, sulfotransferase I: 60% of the sulfate ester groups formed are linked to the C-6 atom of galactosyl residues, the rest to the C-6 atom of N-acetylglucosamine, sulfotransferase II: 23% of the newly formed sulfate ester groups are on galactosyl and 77% on N-acetylglucosaminyl residues
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
partially desulfated
specificity, sulfotransferase I: 60% of the sulfate ester groups formed are linked to the C-6 atom of galactosyl residues, the rest to the C-6 atom of N-acetylglucosamine, sulfotransferase II: 23% of the newly formed sulfate ester groups are on galactosyl and 77% on N-acetylglucosaminyl residues
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
sulfation at position 6 of Gal residues which are adjacent to GlcNAc(6S) or GlcNAc
-
-
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase
-
-
?
3'-phosphoadenylylsulfate + keratan sulfate
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase
-
-
?
additional information

?
-
-
N-acetylglucosamine residues do not act as acceptors
-
-
?
additional information
?
-
-
sulfation of GlcNAc is coupled to enlongation of keratan sulfate chain
-
-
?
additional information
?
-
no activity towards chondroitin, chondroitin sulfate, dermatan sulfate or CDSNS-heparinn
-
-
?
additional information
?
-
-
no activity towards chondroitin, chondroitin sulfate, dermatan sulfate or CDSNS-heparinn
-
-
?
additional information
?
-
-
Gn6ST produces keratan sulfate in cooperation with KSG6ST, inactivation of Gn6ST may lead to macular corneal dystrophy
-
-
?
additional information
?
-
-
loss of GST-4beta causes macular corneal dystrophy
-
-
?
additional information
?
-
sulfation of GlcNAc residues precedes sulfation of Gal residues during biosynthesis of keratan sulfate
-
-
?
additional information
?
-
-
sulfation of GlcNAc residues precedes sulfation of Gal residues during biosynthesis of keratan sulfate
-
-
?
additional information
?
-
-
KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
3'-phosphoadenylyl sulfate + N-acetyllactosamine
adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine
-
-
-
-
?
additional information
?
-
3'-phosphoadenylyl sulfate + keratan

adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
keratan sulfate proteoglycan is expressed in the extracellular matrix or cell surface in numerous tissues, predominantly in those of the cornea, cartilage, and brain
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
pericellular localization of R-10G reactive KS epitopes in perineuronal net-positive neurons in the visual cortex of adult mice
-
-
?
3'-phosphoadenylyl sulfate + keratan
adenosine 3',5'-bisphosphate + keratan 6'-sulfate
pericellular localization of R-10G reactive KS epitopes in perineuronal net-positive neurons in the visual cortex of adult mice
-
-
?
additional information

?
-
-
sulfation of GlcNAc is coupled to enlongation of keratan sulfate chain
-
-
?
additional information
?
-
-
Gn6ST produces keratan sulfate in cooperation with KSG6ST, inactivation of Gn6ST may lead to macular corneal dystrophy
-
-
?
additional information
?
-
-
loss of GST-4beta causes macular corneal dystrophy
-
-
?
additional information
?
-
sulfation of GlcNAc residues precedes sulfation of Gal residues during biosynthesis of keratan sulfate
-
-
?
additional information
?
-
-
sulfation of GlcNAc residues precedes sulfation of Gal residues during biosynthesis of keratan sulfate
-
-
?
additional information
?
-
-
KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview
-
-
?
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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