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Disease on EC 2.8.2.2 - alcohol sulfotransferase and Organism(s) Homo sapiens

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
3alpha(or 20beta)-hydroxysteroid dehydrogenase deficiency
Association Study of CYP17 and HSD11B1 in Polycystic Ovary Syndrome Utilizing Comprehensive Gene Coverage.
Abortion, Spontaneous
Triclosan causes spontaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice.
ACTH-Secreting Pituitary Adenoma
Expression of genes related to corticotropin production and glucocorticoid feedback in corticotroph adenomas of dogs with Cushing's disease.
Acute Kidney Injury
Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice.
Acute Lung Injury
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury.
Adenocarcinoma
Cloning and expression of cDNA encoding human placental estrogen sulfotransferase.
Regulation of estrogen sulfotransferase in human endometrial adenocarcinoma cells by progesterone.
Adenocarcinoma of Lung
Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression.
Adenoma
A compound adrenal medullary tumor (pheochromocytoma and ganglioneuroma) and a cortical adenoma in the ipsilateral adrenal gland. A case report with enzyme histochemical and immunohistochemical studies.
Adrenocorticotropic hormone-independent bilateral adrenocortical macronodular hyperplasia as a distinct subtype of Cushing's syndrome. Enzyme histochemical and ultrastructural study of four cases with a review of the literature.
Histochemical investigation of aldosterone-secreting cells adenoma of the adrenal cortex.
Adrenal Hyperplasia, Congenital
Assisted Reproduction in Congenital Adrenal Hyperplasia.
Gender assignment and medical history of individuals with different forms of intersexuality: evaluation of medical records and the patients' perspective.
Uniparental Isodisomy of Chromosome 1 Unmasking an Autosomal Recessive 3-Beta Hydroxysteroid Dehydrogenase Type II-Related Congenital Adrenal Hyperplasia.
[A novel homozygous mutation p.E25X in the HSD3B2 gene causing salt wasting 3?-hydroxysteroid dehydrogenases deficiency in a Chinese pubertal girl: a delayed diagnosis until recurrent ovary cysts].
Adrenal Rest Tumor
Testicular Adrenal Rest Tumor In Brothers With Novel Mutation In 3-Beta Hydroxysteroid Dehydrogenase -2 Gene.
Adrenocortical Adenoma
Enzyme histocytochemical studies in human adrenocortical adenomas. [I]. Primary aldosteronism.
Adrenocortical Hyperfunction
An inhibitor of 11-? hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells.
Efficacy of trilostane for the treatment of equine Cushing's syndrome.
Nonylphenol-induced hyperadrenalism can be reversed/alleviated by inhibiting of 11-? hydroxysteroid dehydrogenase type 1.
alcohol sulfotransferase deficiency
Gender assignment and medical history of individuals with different forms of intersexuality: evaluation of medical records and the patients' perspective.
Alopecia
Steroid chemistry and hormone controls during the hair follicle cycle.
Alzheimer Disease
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease.
Presence of hydroxysteroid dehydrogenase type 10 in amyloid plaques (APs) of Hsiao's APP-Sw transgenic mouse brains, but absence in APs of Alzheimer's disease brains.
Androgen-Insensitivity Syndrome
Gender assignment and medical history of individuals with different forms of intersexuality: evaluation of medical records and the patients' perspective.
Novel Mutation Among Two Sisters With 17? Hydroxysteroid Dehydrogenase Type 3 Deficiency.
[Proceedings: Male pseudohermaphroditism due to testicular 17 beta hydroxysteroid deshydrogenase deficiency (author's transl)]
Atherosclerosis
Human estrogen sulfotransferase and its related fluorescently labeled decapeptides specifically interact with oxidized low-density lipoprotein.
Interaction of Native- and Oxidized-Low-Density Lipoprotein with Human Estrogen Sulfotransferase.
Breast Neoplasms
A correlation between estrogen sulfotransferase levels and estrogen receptor status in human primary breast carcinoma.
A library approach to the generation of bisubstrate analogue sulfotransferase inhibitors.
A relationship between estrogen sulfurylation and estrogen and progesterone receptor status in human mammary carcinoma.
Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NF?? interplay.
Dependence between estrogen sulfotransferase (SULT1E1) and nuclear transcription factor Nrf-2 regulations via oxidative stress in breast cancer.
Effect of nomegestrol acetate on human estrogen sulfotransferase activity in the hormone-dependent MCF-7 and T-47D breast cancer cell lines.
Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma.
Estrogen sulfotransferase and steroid sulfatase in human breast carcinoma.
Estrogen sulfotransferases in breast and endometrial cancers.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Expression of Estrogen Sulfotransferase 1E1 and Steroid Sulfatase in Breast Cancer: A Immunohistochemical Study.
Expression of hydroxysteroid sulphotransferase is related to estrogen receptor status in human mammary cancer.
Genetic variation in estrogen and progesterone pathway genes and breast cancer risk: an exploration of tumor subtype-specific effects.
Human estrogen sulfotransferase (hEST1) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020).
Immunohistochemical localisation of hydroxysteroid sulphotransferase in human breast carcinoma tissue: a preliminary study.
In situ production of estrogens in human breast carcinoma.
In vitro inhibition of estrogen sulfoconjugation by some 2- and 4-substituted estra-1,3,5(10)-trien-17 beta-ols1a.
Insulin-like growth factor type I and insulin-like growth factor type II stimulate oestradiol-17 beta hydroxysteroid dehydrogenase (reductive) activity in breast cancer cells.
Intracrinology of breast microenvironment: hormonal status in nipple aspirate fluid and its relationship to breast cancer.
Intratumoral estrogen sulfotransferase induction contributes to the anti-breast cancer effects of the dithiocarbamate derivative TM208.
Local biosynthesis and metabolism of oestrogens in the human breast.
Metabolic fate of estradiol in human mammary cancer cells in culture: estrogen sulfate formation and cooperativity exhibited by estrogen sulfotransferase.
Modulation of oestrone sulphatase activity in breast cancer cell lines by growth factors.
Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism.
Progestagen component in combined hormone replacement therapy in postmenopausal women and breast cancer risk: a debated clinical issue.
Promoter Methylation Status of Breast Cancer Susceptibility Gene 1 and 17 Beta Hydroxysteroid Dehydrogenase Type 1 Gene in Sporadic Breast Cancer Patients.
Properties of estrogen and hydroxysteroid sulphotransferases in human mammary cancer.
Quantitative determination of oestradiol-17 beta hydroxysteroid dehydrogenase: increased sensitivity by HPLC separation of the hormones permits the measurement of enzyme activity in cryostat sections.
Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer.
Regulation of estrogen sulfotransferase by estrogen in MCF-7 human mammary cancer cells.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
Steroid sulfatase and estrogen sulfotransferase in normal human tissue and breast carcinoma.
Sulfation of estradiol in human epidermal keratinocyte.
The effect of epidermal growth factor, transforming growth factor and breast tumour homogenates on the activity of oestradiol 17 beta hydroxysteroid dehydrogenase in cultured adipose tissue.
The regulation of hydroxysteroid 17?-dehydrogenase type 1 and 2 gene expression in breast cancer cell lines by estradiol, dihydrotestosterone, microRNAs, and genes related to breast cancer.
The relationship between 17 beta hydroxysteroid dehydrogenase and breast tumour site and size.
The role of 17?HSDs in breast tissue and breast cancers.
[Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
Carcinogenesis
Dependence between estrogen sulfotransferase (SULT1E1) and nuclear transcription factor Nrf-2 regulations via oxidative stress in breast cancer.
Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma.
Rat liver 3 alpha-hydroxysteroid dehydrogenase.
[Expression of estrogen sulfotransferase in breast tissues and the regulation of ESTmRNA by estrogen]
Carcinoma
11? hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma.
17? hydroxysteroid dehydrogenase type 12 (HSD17B12) is a marker of poor prognosis in ovarian carcinoma.
Clinicopathological Significance of Estrogen Receptor ? and Estrogen Synthesizing/Metabolizing Enzymes in Urothelial Carcinoma of Urinary Bladder.
Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma.
Identification of Hydroxysteroid (17?) dehydrogenase type 12 (HSD17B12) as a CD8(+) T-cell-defined human tumor antigen of human carcinomas.
Immunohistochemical localisation of hydroxysteroid sulphotransferase in human breast carcinoma tissue: a preliminary study.
Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors.
Steroid sulfatase and estrogen sulfotransferase in human carcinomas.
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma.
Carcinoma, Hepatocellular
Hydroxysteroid 17-Beta Dehydrogenase 6 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Hepatocellular Carcinoma.
Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure.
Carcinoma, Intraductal, Noninfiltrating
Immunolocalization of estrogen-producing and metabolizing enzymes in benign breast disease: comparison with normal breast and breast carcinoma.
Carcinoma, Non-Small-Cell Lung
11? hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma.
Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen.
Carcinoma, Ovarian Epithelial
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer.
Cholangitis, Sclerosing
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Chorioamnionitis
The effects of chorioamnionitis and betamethasone on 11beta hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor in preterm human placenta.
Choriocarcinoma
Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Colitis, Ulcerative
Bacterial bile metabolising gene abundance in Crohn's, ulcerative colitis and type 2 diabetes metagenomes.
Coronary Artery Disease
Mediastinal adipose tissue expresses a pathogenic profile of 11 ?-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease.
Crohn Disease
Bacterial bile metabolising gene abundance in Crohn's, ulcerative colitis and type 2 diabetes metagenomes.
Cryptorchidism
Effect of cryptorchidism and orchidopexy on 3B hydroxysteroid dehydrogenase activity in rat testicle.
Expression of anti-Müllerian hormone, CDKN1B, connexin 43, androgen receptor and steroidogenic enzymes in the equine cryptorchid testis.
Cystadenoma, Serous
Activation of Androgens by Hydroxysteroid (17{beta}) Dehydrogenase 1 in Vivo as a Cause of Prenatal Masculinization and Ovarian Benign Serous Cystadenomas.
Cystic Fibrosis
Elevation of hepatic sulphotransferase activities in mice with resistance to cystic fibrosis.
Depression, Postpartum
Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study.
Diabetes Mellitus
11? Hydroxysteroid dehydrogenase - 1 activity in type 2 diabetes mellitus: a comparative study.
Bacterial bile metabolising gene abundance in Crohn's, ulcerative colitis and type 2 diabetes metagenomes.
Diabetes Mellitus, Type 1
Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes.
Diabetes Mellitus, Type 2
11? Hydroxysteroid dehydrogenase - 1 activity in type 2 diabetes mellitus: a comparative study.
Bacterial bile metabolising gene abundance in Crohn's, ulcerative colitis and type 2 diabetes metagenomes.
Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.
Lower Renal Function Is Associated With Derangement of 11-? Hydroxysteroid Dehydrogenase in Type 2 Diabetes.
Mapping and association studies of diabetes related genes in the pig.
Sex-specific effect of estrogen sulfotransferase on mouse models of type 2 diabetes.
Disorder of Sex Development, 46,XY
Ten years experience with masculinizing genitoplasty in male pseudohermaphroditism due to 17 beta-hydroxysteroid dehydrogenase deficiency.
[Proceedings: Male pseudohermaphroditism due to testicular 17 beta hydroxysteroid deshydrogenase deficiency (author's transl)]
Disorders of Sex Development
The novel founder homozygous V225M mutation in the HSD17B3 gene causes aberrant splicing and XY-DSD.
Ectromelia
The genome of swinepox virus.
Endometrial Hyperplasia
Changes in lipoproteins with various sex steroids.
In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia.
Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice.
Endometrial Neoplasms
Characterization of cytosolic estrogen sulfotransferase from RL95-2 endometrial cancer cells.
Estrogen sulfotransferase and sulfatase: Roles in the regulation of estrogen activity in human uterine endometrial carcinomas.
Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma.
The sulfatase pathway as estrogen supply in endometrial cancer.
Endometriosis
Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells.
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
Estrogen metabolizing enzymes in endometrium and endometriosis.
Expression of aromatase and estrogen sulfotransferase in eutopic and ectopic endometrium: evidence for unbalanced estradiol production in endometriosis.
Seven Hormonal Biomarkers for Diagnosing Endometriosis: Meta-Analysis and Adjusted Indirect Comparison of Diagnostic Test Accuracy.
Essential Hypertension
Aldosterone synthase C-344T, angiotensin II type 1 receptor A1166C and 11-? hydroxysteroid dehydrogenase G534A gene polymorphisms and essential hypertension in the population of Odisha, India.
Fatty Liver
Associations of Hydroxysteroid 17-beta Dehydrogenase 13 Variants with Liver Histology in Chinese Patients with Metabolic-associated Fatty Liver Disease.
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target.
Folic Acid Deficiency
Effects of folic acid deficiency in pregnant Wistar rats on the activities of D5-3 beta hydroxysteroid dehydrogenase and glucose-6 phosphate dehydrogenase in the ovaries of their litters.
Gastroesophageal Reflux
Do bile acids reflux into the esophagus? A study in normal subjects and patients with gastroesophageal reflux disease.
Gastrointestinal Stromal Tumors
Hydroxysteroid 11-Beta Dehydrogenase 1 Overexpression with Copy-Number Gain and Missense Mutations in Primary Gastrointestinal Stromal Tumors.
Glioma
Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma.
Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: relevance of AMPA receptor-mediated NO signaling.
Gonadal Dysgenesis
Gender assignment and medical history of individuals with different forms of intersexuality: evaluation of medical records and the patients' perspective.
Hemangioma
Evidence by molecular profiling for a placental origin of infantile hemangioma.
Hepatitis
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Hepatitis, Chronic
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Herpes Zoster
Effects of culture conditions on the developmental programme of mouse blastocysts.
Quantitative proteomic reveals the dynamic of protein profile during final oocyte maturation in zebrafish.
The genomic transcriptional response of female fathead minnows (Pimephales promelas) to an acute exposure to the androgen, 17beta-trenbolone.
Hirsutism
[Hirsutism with partial blockage of 3 beta OL hydroxysteroid dehydrogenase (author's transl)]
Hydatidiform Mole
Histochemical demonstration of hydroxysteroid dehydrogenases in hydatidiform mole.
[Serum and tissue 17 beta hydroxysteroid dehydrogenase and estrogens in hydatidiform mole]
Hyperaldosteronism
Enzyme histocytochemical studies in human adrenocortical adenomas. [I]. Primary aldosteronism.
Hyperglycemia
Dexamethasone-induced hyperglycemia in obese Avy/a (viable yellow) female mice entails preferential induction of a hepatic estrogen sulfotransferase.
Hypertension
Apparent Mineralocorticoid Excess by a Novel Mutation and Epigenetic Modulation by HSD11B2 Promoter Methylation.
Common Variation at the 11-Beta Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Gene Is Associated with Left Ventricular Mass.
Does the maternal micronutrient deficiency (copper or zinc or vitamin E) modulate the expression of placental 11 beta hydroxysteroid dehydrogenase-2 per se predispose offspring to insulin resistance and hypertension in later life?
Maternal hypertension and progeny blood pressure: role of aldosterone and 11beta-HSD.
Hyperthyroidism
Characterization of iodothyronine sulfotransferase activity in rat liver.
Hypokalemia
[Cushing syndrome by ectopic ACTH secretion: analysis of the physiopathologic mechanism of hypokalemia. Report of two cases]
Hypothyroidism
Characterization of iodothyronine sulfotransferase activity in rat liver.
Urinary cortisol metabolites in the assessment of peripheral thyroid hormone action: overt and subclinical hypothyroidism.
Infertility
[17 beta hydroxysteroid dehydrogenase and creatine phosphokinase activities and the levels of sex hormones and their receptors in the uterus of patients with fibromyoma or endocrine sterility]
Infertility, Male
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Insulin Resistance
Assessment of 11-? hydroxysteroid dehydrogenase (11-?HSD1) 4478T>G and tumor necrosis factor-? (TNF-?)-308G>A polymorphisms with obesity and insulin resistance in Asian Indians in North India.
Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women.
Does the maternal micronutrient deficiency (copper or zinc or vitamin E) modulate the expression of placental 11 beta hydroxysteroid dehydrogenase-2 per se predispose offspring to insulin resistance and hypertension in later life?
Effects of 11?-hydroxysteroid dehydrogenase-1 Inhibition on Hepatic Glycogenolysis and Gluconeogenesis.
Sex- and Tissue-Specific Role of Estrogen Sulfotransferase in Energy Homeostasis and Insulin Sensitivity.
Sexual dimorphism in 11 beta hydroxysteroid dehydrogenase activity and its relation to fat distribution and insulin sensitivity; a study in hypopituitary subjects.
Intellectual Disability
Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation.
Intestinal Diseases
Elevation of hepatic sulphotransferase activities in mice with resistance to cystic fibrosis.
Kidney Diseases
Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes.
Kidney Failure, Chronic
Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes.
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats.
Leiomyoma
[17 beta hydroxysteroid dehydrogenase and creatine phosphokinase activities and the levels of sex hormones and their receptors in the uterus of patients with fibromyoma or endocrine sterility]
Leukemia
Analysis of differential gene regulation in adequate versus inadequate secretory-phase endometrial complementary deoxyribonucleic acid populations from the rhesus monkey.
Different T-cell subtypes are associated with pathologically distinct forms of Moloney leukemia virus (M-MuLV)-induced lymphoma.
Liver Cirrhosis, Alcoholic
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Liver Cirrhosis, Biliary
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Liver Diseases
17-Beta Hydroxysteroid Dehydrogenase 13 Deficiency Does Not Protect Mice From Obesogenic Diet Injury.
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.
Associations of Hydroxysteroid 17-beta Dehydrogenase 13 Variants with Liver Histology in Chinese Patients with Metabolic-associated Fatty Liver Disease.
Characterization of Essential Domains in HSD17B13 for Cellular Localization and Enzymatic Activity.
Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers.
HSD17B13 rs72613567 protects against liver diseases and histological progression of nonalcoholic fatty liver disease: a systematic review and meta-analysis.
Hydroxysteroid 17-? dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target.
Reduced hepatic content of dehydroepiandrosterone sulphotransferase in chronic liver diseases.
Reply to "Does the HSD17B13 rs72613567 splice variant actually yield a new type of alternative splicing".
Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis.
Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease.
Liver Diseases, Alcoholic
Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target.
Liver Neoplasms
16alpha-hydroxyestrone inhibits estrogen sulfotransferase activity in human liver cancer cells.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Lung Neoplasms
Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen.
Lymphoma
Different T-cell subtypes are associated with pathologically distinct forms of Moloney leukemia virus (M-MuLV)-induced lymphoma.
Magnesium Deficiency
Magnesium deficiency in pregnant rats alters methylation of specific cytosines in the hepatic hydroxysteroid dehydrogenase-2 promoter of the offspring.
Malnutrition
Periconceptional undernutrition and being a twin each alter kidney development in the sheep fetus during early gestation.
Mammary Neoplasms, Animal
Histochemical evaluation of ovarian hydroxysteroid dehydrogenase activity in bitches with mammary neoplasms.
Metabolic Diseases
Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.
Estrogen sulfotransferase: intracrinology meets metabolic diseases.
Mycetoma
Polymorphisms in catechol-O-methyltransferase and cytochrome p450 subfamily 19 genes predispose towards Madurella mycetomatis-induced mycetoma susceptibility.
Myxoma
The genome of swinepox virus.
Neoplasm Metastasis
Lipid metabolism regulator human hydroxysteroid dehydrogenase-like 2 (HSDL2) modulates cervical cancer cell proliferation and metastasis.
Neoplasms
17 beta Hydroxysteroid dehydrogenase 1 "pseudogene" is differentially transcribed: still a candidate for the breast-ovarian cancer susceptibility gene (BRCA1).
A correlation between estrogen sulfotransferase levels and estrogen receptor status in human primary breast carcinoma.
A relationship between estrogen sulfurylation and estrogen and progesterone receptor status in human mammary carcinoma.
Alpha-hydroxylation of tamoxifen and toremifene by human and rat cytochrome P450 3A subfamily enzymes.
Aromatase and intracrinology of estrogen in hormone-dependent tumors.
Assessment of 11-? hydroxysteroid dehydrogenase (11-?HSD1) 4478T>G and tumor necrosis factor-? (TNF-?)-308G>A polymorphisms with obesity and insulin resistance in Asian Indians in North India.
Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events.
Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma.
Demonstration of hydroxysteroid dehydrogenases and testosterone in the Sertoli-Leydig cell tumor (androblastoma) tissue of the human ovary: an enzyme histochemical and immunohistochemical study.
Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen.
Estrogen inhibits cell proliferation through in situ production in human thymoma.
Estrogen sulfotransferase (SULT1E1) expression in benign and malignant human bone tumors.
Estrogen sulfotransferases in breast and endometrial cancers.
Estrogen sulfurylation as an alternative indicator of hormone dependence in human breast cancer.
Estrogen-like effects of tamoxifen on human endometrial carcinoma transplanted into nude mice.
Expression level of enzymes related to in situ estrogen synthesis and clinicopathological parameters in breast cancer patients.
Expression of glucocorticoid receptor and 11beta hydroxysteroid dehydrogenase in a case of pulmonary epithelioid haemangioendothelioma.
Fecal hydroxysteroid dehydrogenase activities in vegetarian Seventh-Day Adventists, control subjects, and bowel cancer patients.
Genomic and non-genomic effects of glucocorticoids: implications for breast cancer.
HSDL2 Acts as a Promoter in Pancreatic Cancer by Regulating Cell Proliferation and Lipid Metabolism.
Human type 1 estrogen sulfotransferase: catecholestrogen metabolism and potential involvement in cancer promotion.
Hydroxysteroid 11-Beta Dehydrogenase 1 Overexpression with Copy-Number Gain and Missense Mutations in Primary Gastrointestinal Stromal Tumors.
Identification of Hydroxysteroid (17?) dehydrogenase type 12 (HSD17B12) as a CD8(+) T-cell-defined human tumor antigen of human carcinomas.
Increased estrogen sulfation of estradiol 17beta-D-glucuronide in metastatic tumor rat livers.
Intratumoral estrogen sulfotransferase induction contributes to the anti-breast cancer effects of the dithiocarbamate derivative TM208.
Lipid metabolism regulator human hydroxysteroid dehydrogenase-like 2 (HSDL2) modulates cervical cancer cell proliferation and metastasis.
Long-chain fatty acids inhibit human members of the aldo-keto reductase 1C subfamily.
Metabolomic Analysis of the Effects of Leptin Replacement Therapy in Patients with Lipodystrophy.
Modulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells.
Nature-derived anticancer steroids outside cardica glycosides.
Promoter Methylation Status of Breast Cancer Susceptibility Gene 1 and 17 Beta Hydroxysteroid Dehydrogenase Type 1 Gene in Sporadic Breast Cancer Patients.
Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
Sulfation of estradiol in human epidermal keratinocyte.
Testicular Adrenal Rest Tumor In Brothers With Novel Mutation In 3-Beta Hydroxysteroid Dehydrogenase -2 Gene.
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors.
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Non-alcoholic Fatty Liver Disease
17-Beta Hydroxysteroid Dehydrogenase 13 Deficiency Does Not Protect Mice From Obesogenic Diet Injury.
Characterization of Essential Domains in HSD17B13 for Cellular Localization and Enzymatic Activity.
HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non-Alcoholic Fatty Liver Disease.
Hydroxysteroid 17-? dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.
Inhibition of LXR signaling by SULT2B1b promotes liver regeneration after partial hepatectomy in mouse models of nonalcoholic fatty liver disease.
Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target.
NAFLD and renal function in children: is there a genetic link?
Pediatric non-alcoholic fatty liver disease and kidney function: Effect of HSD17B13 variant.
Reply to "Does the HSD17B13 rs72613567 splice variant actually yield a new type of alternative splicing".
Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease.
The HSD17B13 rs72613567 variant is associated with lower levels of albuminuria in patients with biopsy-proven nonalcoholic fatty liver disease.
Obesity
Assessment of 11-? hydroxysteroid dehydrogenase (11-?HSD1) 4478T>G and tumor necrosis factor-? (TNF-?)-308G>A polymorphisms with obesity and insulin resistance in Asian Indians in North India.
Genetic polymorphisms and obesity influence estradiol decline during the menopause.
Glucocorticoids and neuroendocrine function.
Mapping and association studies of diabetes related genes in the pig.
The inflammatory consequences of psychologic stress: relationship to insulin resistance, obesity, atherosclerosis and diabetes mellitus, type II.
Obesity, Abdominal
GH effect on enzyme activity of 11betaHSD in abdominal obesity is dependent on treatment duration.
Osteoporosis
Highly Potent 17?-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy.
Type 2 17-? hydroxysteroid dehydrogenase as a novel target for the treatment of osteoporosis.
Ovarian Neoplasms
Role of Hydroxysteroid Dehydrogenase-Like 2 (HSDL2) in Human Ovarian Cancer.
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer.
Pituitary Neoplasms
Pathophysiological changes associated with the exposure of sustained delivery of glucocorticoids on pituitary adenoma cell line.
Pre-Eclampsia
Hydroxysteroid (17-?) dehydrogenase 1 is dysregulated by miR-210 and miR-518c that are aberrantly expressed in preeclamptic placentas: a novel marker for predicting preeclampsia.
Plasma level of hydroxysteroid (17-?) dehydrogenase 1 in the second trimester is an independent risk factor for predicting preeclampsia after adjusting for the effects of mean blood pressure, bilateral notching and plasma level of soluble fms-like tyrosine kinase 1/placental growth factor ratio.
Primary Ovarian Insufficiency
3 beta hydroxysteroid dehydrogenase autoantibodies in patients with idiopathic premature ovarian failure target N- and C-terminal epitopes.
Prostatic Neoplasms
Androgens and the molecular epidemiology of prostate cancer.
Molecular expression of 17 beta hydroxysteroid dehydrogenase types in relation to their activity in intact human prostate cancer cells.
Preclinical Pharmacokinetics, Tissue Distribution and Primary Safety Evaluation of a Novel Curcumin Analogue H10 Suspension, a Potential 17? Hydroxysteroid Dehydrogenase Type 3 Inhibitor.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
The Impact of Germline Genetic Variations in Hydroxysteroid (17-Beta) Dehydrogenases on Prostate Cancer Outcomes After Prostatectomy.
Proteinuria
Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat.
Renal Insufficiency, Chronic
Lower Renal Function Is Associated With Derangement of 11-? Hydroxysteroid Dehydrogenase in Type 2 Diabetes.
Rhinitis, Allergic
The expression of 11 beta hydroxysteroid dehydrogenase in severe allergic rhinitis.
Sarcoma
Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study.
Sarcoma, Endometrial Stromal
Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study.
Sertoli Cell-Only Syndrome
Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure.
Sertoli-Leydig Cell Tumor
Demonstration of hydroxysteroid dehydrogenases and testosterone in the Sertoli-Leydig cell tumor (androblastoma) tissue of the human ovary: an enzyme histochemical and immunohistochemical study.
Sleep Deprivation
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Smallpox
The genome of swinepox virus.
steroid 11beta-monooxygenase deficiency
The prevalence of late onset congenital adrenal hyperplasia in hirsute women from Central Anatolia.
Uterine Cervical Neoplasms
Lipid metabolism regulator human hydroxysteroid dehydrogenase-like 2 (HSDL2) modulates cervical cancer cell proliferation and metastasis.
Vaccinia
The genome of swinepox virus.
Virus Diseases
The genome of fowlpox virus.
Wilms Tumor
New frontiers on the molecular underpinnings of hypospadias according to severity.