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Information on EC 2.8.1.14 - tRNA-5-taurinomethyluridine 2-sulfurtransferase

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IUBMB Comments
The enzyme, found in mitochondria, catalyses formation of 5-taurinomethyl-2-thiouridine in the wobble position of mitochondrial tRNAGln, tRNALys and tRNAGlu.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
a [protein]-S-sulfanyl-L-cysteine
+
5-taurinomethyluracil34 in tRNA
+
+
=
a [protein]-L-cysteine
+
5-taurinomethyl-2-thiouracil34 in tRNA
+
+
+
Synonyms
MTO2, MTU1, SLM3, TRMU, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [protein]-S-sulfanyl-L-cysteine + 5-taurinomethyluracil34 in tRNA + ATP + reduced acceptor = a [protein]-L-cysteine + 5-taurinomethyl-2-thiouracil34 in tRNA + AMP + diphosphate + acceptor
show the reaction diagram
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-
-
-
PATHWAY SOURCE
PATHWAYS
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