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Information on EC 2.8.1.13 - tRNA-uridine 2-sulfurtransferase

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EC Tree
     2 Transferases
         2.8 Transferring sulfur-containing groups
             2.8.1 Sulfurtransferases
                2.8.1.13 tRNA-uridine 2-sulfurtransferase
IUBMB Comments
The enzyme, found in bacteria, catalyses formation of the 2-thiouridine modification in the wobble position of tRNAGln, tRNALys and tRNAGlu.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
a [protein]-S-sulfanyl-L-cysteine
+
uacil34 in tRNA
+
+
=
a [protein]-L-cysteine
+
2-thiouracil34 in tRNA
+
+
+
Synonyms
MnmA, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a [protein]-S-sulfanyl-L-cysteine + uacil34 in tRNA + ATP + reduced acceptor = a [protein]-L-cysteine + 2-thiouracil34 in tRNA + AMP + diphosphate + acceptor
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