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Information on EC - molybdopterin synthase

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EC Tree
     2 Transferases
         2.8 Transferring sulfur-containing groups
             2.8.1 Sulfurtransferases
       molybdopterin synthase
IUBMB Comments
Catalyses the synthesis of molybdopterin from cyclic pyranopterin monophosphate. Two sulfur atoms are transferred to cyclic pyranopterin monophosphate in order to form the characteristic ene-dithiol group found in the molybdenum cofactor. Molybdopterin synthase consists of two large subunits forming a central dimer and two small subunits (molybdopterin-synthase sulfur-carrier proteins) that are thiocarboxylated at the C-terminus by EC, molybdopterin synthase sulfurtransferase. The reaction occurs in prokaryotes and eukaryotes.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
CnxG, CnxH, MoaB, MoaD, MoaE, MoaX, MPT synthase, Rv3323c, TTHA0341, more
cyclic pyranopterin phosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O = molybdopterin + 2 molybdopterin-synthase sulfur-carrier protein
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