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Information on EC 2.7.8.44 - teichoic acid glycerol-phosphate primase

for references in articles please use BRENDA:EC2.7.8.44

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IUBMB Comments

Involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls. This enzyme adds the first glycerol unit to the disaccharide linker of the teichoic acid.

The enzyme appears in viruses and cellular organisms

Synonyms
cdp-glycerol:n-acetyl-beta-d-mannosaminyl-1,4-n-acetyl-d-glucosaminyldiphosphoundecaprenyl glycerophosphotransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CDP-glycerol + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = CDP + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis, poly(glycerol phosphate) wall teichoic acid biosynthesis, poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis), poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)
Highest Expressing Human Cell Lines
Cell Line Links Gene Links