Information on EC 2.7.8.37 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase

for references in articles please use BRENDA:EC2.7.8.37
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The expected taxonomic range for this enzyme is: Escherichia coli

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EC NUMBER
COMMENTARY hide
2.7.8.37
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RECOMMENDED NAME
GeneOntology No.
alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(aminomethyl)phosphonate degradation
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glyphosate degradation III
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methylphosphonate degradation I
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methylphosphonate degradation II
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Phosphonate and phosphinate metabolism
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SYSTEMATIC NAME
IUBMB Comments
ATP:methylphosphonate 5-triphosphoribosyltransferase
Isolated from the bacterium Escherichia coli.
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + H2O
adenine + D-ribose-5-triphosphate
show the reaction diagram
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?
ATP + methylphosphonate
adenine + alpha-D-ribose-1-methylphosphonate-5-triphosphate
show the reaction diagram
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?
GTP + H2O
guanine + D-ribose-5-triphosphate
show the reaction diagram
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?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
13 - 350
ATP
83 - 340
GTP
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PDB
SCOP
CATH
UNIPROT
ORGANISM
Escherichia coli (strain K12);
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
GST fusion proteins: GSTrap column, His-tagged proteins: HisTrap column
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
GST fusion proteins of PhnI and PhnL expressed in Escherichia coli BL21(DE3), His-tagged PhnG and PhnH expressed in Escherichia coli BL21(DE3)
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Show AA Sequence (416 entries)
Please use the Sequence Search for a specific query.
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LINKS TO OTHER DATABASES (specific for EC-Number 2.7.8.37)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)