Information on EC 2.7.8.37 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase

for references in articles please use BRENDA:EC2.7.8.37
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:


The expected taxonomic range for this enzyme is: Escherichia coli

EC NUMBER
COMMENTARY hide
2.7.8.37
-
RECOMMENDED NAME
GeneOntology No.
alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine
show the reaction diagram
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
aminomethylphosphonate degradation
-
-
glyphosate degradation III
-
-
methylphosphonate degradation I
-
-
methylphosphonate degradation II
-
-
Phosphonate and phosphinate metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:methylphosphonate 5-triphosphoribosyltransferase
Isolated from the bacterium Escherichia coli.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + H2O
adenine + D-ribose-5-triphosphate
show the reaction diagram
-
-
-
-
?
ATP + methylphosphonate
adenine + alpha-D-ribose-1-methylphosphonate-5-triphosphate
show the reaction diagram
-
-
-
-
?
GTP + H2O
guanine + D-ribose-5-triphosphate
show the reaction diagram
-
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
13 - 350
ATP
83 - 340
GTP
PDB
SCOP
CATH
ORGANISM
UNIPROT
Escherichia coli (strain K12)
Escherichia coli (strain K12)
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
GST fusion proteins: GSTrap column, His-tagged proteins: HisTrap column
-
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
GST fusion proteins of PhnI and PhnL expressed in Escherichia coli BL21(DE3), His-tagged PhnG and PhnH expressed in Escherichia coli BL21(DE3)
-
Show AA Sequence (426 entries)
Please use the Sequence Search for a specific query.