Information on EC 2.7.8.31 - undecaprenyl-phosphate glucose phosphotransferase

for references in articles please use BRENDA:EC2.7.8.31
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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.7.8.31
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RECOMMENDED NAME
GeneOntology No.
undecaprenyl-phosphate glucose phosphotransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
acetan biosynthesis
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xanthan biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:ditrans,octacis-undecaprenyl-phosphate glucose phosphotransferase
The enzyme is involved in biosynthesis of xanthan.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
pv. citri
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Manually annotated by BRENDA team
pv. oryzae
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
the GumD protein catalyses the first step of xanthan production and is responsible for the addition of the first glucose molecule to the isoprenoid acceptor molecule
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-galactose + undecaprenyl phosphate
UMP + alpha-D-galactosyl-diphosphoundecaprenol
show the reaction diagram
UDP-alpha-D-glucose + undecaprenyl phosphate
UMP + alpha-D-glucosyl-diphosphoundecaprenol
show the reaction diagram
UDP-glucose + ditrans,octacis-undecaprenyl phosphate
UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
UDP-glucose + ditrans,octacis-undecaprenyl phosphate
UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol
show the reaction diagram
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
54300
calculated from amino acid sequence
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
a recombinant plasmid carrying the gumD gene of Xanthomonas campestris restored polysaccharide synthesis to bacitracin-resistant exopolysaccharide-negative mutants of Xanthomonas campestris and Sphingomonas strains
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expressed in Escherichia coli C43(DE3) cells
the C-terminal portion of GumD is cloned into broad-host-range vector pRK404, producing plasmid pCD2. The C-terminal domain of the gumD gene product is sufficient for its glucosyl-1-phosphate transferase activity
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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
mutation of rpfG leads to up-regulation of glycosyltransferase gene gumD
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
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the enzyme is involved in biosynthesis of xanthan, an industrially important exopolysaccharide
Show AA Sequence (534 entries)
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