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Information on EC 2.7.8.2 - diacylglycerol cholinephosphotransferase and Organism(s) Arabidopsis thaliana and UniProt Accession O82567

for references in articles please use BRENDA:EC2.7.8.2
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EC Tree
IUBMB Comments
1-Alkyl-2-acylglycerol can act as acceptor; this activity was previously listed separately.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: O82567
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
cholinephosphotransferase, choline phosphotransferase, cept1, paf-cpt, dtt-insensitive cholinephosphotransferase, diacylglycerol cholinephosphotransferase, phosphorylcholine glyceride transferase, 1,2-diacylglycerol cholinephosphotransferase, aapt1, phosphatidylcholine:diacylglycerol cholinephosphotransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1-alkyl-2-acetyl-m-glycerol:CDP-choline choline phosphotransferase
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1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase
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1-alkyl-2-acetylglycerol cholinephosphotransferase
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AAPT
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alkylacylglycerol choline phosphotransferase
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alkylacylglycerol cholinephosphotransferase
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aminoalcoholphosphotransferase
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CDP-choline diglyceride phosphotransferase
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CEPT
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cholinephosphotransferase
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cholinephosphotransferase, 1-alkyl-2-acetylglycerol
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cholinephosphotransferase, diacylglycerol
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CPT
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cytidine diphosphocholine glyceride transferase
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cytidine diphosphorylcholine diglyceride transferase
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diacylglycerol choline phosphotransferase
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phosphocholine diacylglyceroltransferase
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phosphorylcholine-glyceride transferase
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sn-1,2-diacylglycerol cholinephosphotransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
substituted phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase
1-Alkyl-2-acylglycerol can act as acceptor; this activity was previously listed separately.
CAS REGISTRY NUMBER
COMMENTARY hide
77237-98-0
formerly, EC 2.7.8.16
9026-13-5
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CDP-choline + 1,2-diacylglycerol
CMP + a phosphatidylcholine
show the reaction diagram
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r
CDP-ethanolamine + 1,2-diacylglycerol
CMP + phosphatidylethanolamine
show the reaction diagram
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r
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
isoenzyme AAPT1, 30% inhibition at 0.1 mM, AAPT2, 18% inhibition at 0.1 mM
CMP
isozyme AAPT1, 43% inhibition at 2 mM, AAPT2 14% inhibition at 2 mM
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
and O82568, dual-specificity enzymes, activities of EC 2.7.8.1 and EC 2.7.8.2
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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very low levels of hydroxy fatty acid are detected when FAH12 (fatty acid hydroxylase) is expressed in seeds of the Arabidopsis rod1 mutant, which contains a lesion in PDCT. A castor PDCT enzyme encoded by the RcROD1 gene increases hydroxy fatty acid levels when coexpressed with FAH12 (fatty acid hydroxylase)
physiological function
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PDCT is required for the efficient metabolism of engineered hydroxy fatty acids in Arabidopsis thaliana seeds
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
AAPT1_ARATH
389
8
43542
Swiss-Prot
Mitochondrion (Reliability: 5)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Goode, J.H.; Dewey, R.E.
Characterization of aminoalcoholphosphotransferases from Arabidopsis thaliana and soybean
Plant Physiol. Biochem.
37
445-457
1999
Glycine max, Arabidopsis thaliana (O82567)
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Manually annotated by BRENDA team
Hu, Z.; Ren, Z.; Lu, C.
The phosphatidylcholine diacylglycerol cholinephosphotransferase is required for efficient hydroxy fatty acid accumulation in transgenic Arabidopsis
Plant Physiol.
158
1944-1954
2012
Arabidopsis thaliana
Manually annotated by BRENDA team