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Information on EC 2.7.8.13 - phospho-N-acetylmuramoyl-pentapeptide-transferase

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IUBMB Comments
In Gram-negative and some Gram-positive organisms the L-lysine is replaced by meso-2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm), which is combined with adjacent residues through its L-centre. The undecaprenol involved is ditrans,octacis-undecaprenol (for definitions, click here).
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The enzyme appears in viruses and cellular organisms
Synonyms
MraY, MraY protein, MraY transferase, MraY translocase, phospho-MurNAc-pentapeptide transferase, phospho-MurNAc-pentapeptide translocase, phospho-N-acetyl-muramyl-pentapeptide translocase, phospho-N-acetylmuramoyl pentapeptide translocase, phospho-N-acetylmuramoyl-pentapeptide translocase, phospho-N-acetylmuramoylpentapeptidetransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
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