Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.7.8.1 - ethanolaminephosphotransferase

for references in articles please use BRENDA:EC2.7.8.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
UNIPROT: Q8WU57 not found.
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
ept, ethanolaminephosphotransferase, ethanolamine phosphotransferase, hept1, cpt1p, ept1p, diacylglycerol ethanolaminephosphotransferase, cdp-ethanolamine:diacylglycerol ethanolaminephosphotransferase, selenoprotein 1, choline-ethanolamine phosphotransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
AAPT
-
-
-
-
aminoalcoholphosphotransferase
-
-
-
-
CDP-ethanolamine diglyceride phosphotransferase
-
-
-
-
CEPT1
-
-
-
-
diacylglycerol ethanolaminephosphotransferase
-
-
-
-
EPT
-
-
-
-
ethanolamine phosphotransferase
-
-
-
-
ethanolaminephosphotransferase, diacylglycerol
-
-
-
-
phosphorylethanolamine-glyceride transferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
substituted phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
CDP-ethanolamine:1,2-diacyl-sn-glycerol ethanolaminephosphotransferase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9026-19-1
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CDP-ethanolamine + 1,2-diacylglycerol
CMP + a phosphatidylethanolamine
show the reaction diagram
enzyme specifically uses CDP-ethanolamine as the phosphobase donor
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
or Mn2+, required. Activity increases with concentration of Mg2+ at least up to 30 mM, no activation below 5 mM
Mn2+
or Mg2+, required. Maximal activity at 5 mM Mn2+
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0018
CDP-ethanolamine
pH 8.0, 37°C
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
high expression in cerebellum
Manually annotated by BRENDA team
additional information
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q8WU57_HUMAN
258
0
29487
TrEMBL
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Horibata, Y.; Hirabayashi, Y.
Identification and characterization of human ethanolaminephosphotransferase1
J. Lipid Res.
48
503-508
2007
Homo sapiens (Q8WU57), Homo sapiens (Q9C0D9), Homo sapiens
Manually annotated by BRENDA team