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The taxonomic range for the selected organisms is: Synechocystis sp.
The enzyme appears in selected viruses and cellular organisms
Synonyms
udp-glucose pyrophosphorylase, ugpase, udpg-pyrophosphorylase, udpgp, udp-glc pyrophosphorylase, udpglucose pyrophosphorylase, glucose-1-phosphate uridylyltransferase, udpg pyrophosphorylase, utp-glucose-1-phosphate uridylyltransferase, uridine diphosphoglucose pyrophosphorylase,
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cyanobacterial UDP-Glc PPase
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glucose 1-phosphate uridylyltransferase
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glucose-1-phosphate uridylyltransferase
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UDP glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDPG phosphorylase
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UDPG pyrophosphorylase
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UDPglucose pyrophosphorylase
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uridine 5'-diphosphoglucose pyrophosphorylase
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uridine diphosphate-D-glucose pyrophosphorylase
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uridine diphosphoglucose pyrophosphorylase
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uridine-diphosphate glucose pyrophosphorylase
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uridylyltransferase, glucose 1-phosphate
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nucleotidyl group transfer
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UTP:alpha-D-glucose-1-phosphate uridylyltransferase
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UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
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enzyme is highly specific for UTP and glucose 1-phosphate
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additional information
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additional information
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no substrates: dTTP, CTP, ATP, and GTP, Glc-1P, GlcNAc-1P, Gal-1P, and Man-1P
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additional information
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no substrates: dTTP, CTP, ATP, and GTP, Glc-1P, GlcNAc-1P, Gal-1P, and Man-1P
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0.085 - 0.088
alpha-D-glucose 1-phosphate
0.085
alpha-D-glucose 1-phosphate
wild-type, pH 7.5, 37°C
0.088
alpha-D-glucose 1-phosphate
mutant A8G, pH 7.5, 37°C
0.18
UTP
wild-type, pH 7.5, 37°C
0.35
UTP
mutant A8G, pH 7.5, 37°C
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0.45 - 0.48
alpha-D-glucose 1-phosphate
0.45
alpha-D-glucose 1-phosphate
wild-type, pH 7.5, 37°C
0.48
alpha-D-glucose 1-phosphate
mutant A8G, pH 7.5, 37°C
0.47
UTP
wild-type, pH 7.5, 37°C
0.48
UTP
mutant A8G, pH 7.5, 37°C
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5.33 - 5.5
alpha-D-glucose 1-phosphate
5.33
alpha-D-glucose 1-phosphate
wild-type, pH 7.5, 37°C
5.5
alpha-D-glucose 1-phosphate
mutant A8G, pH 7.5, 37°C
1.38
UTP
mutant A8G, pH 7.5, 37°C
2.67
UTP
wild-type, pH 7.5, 37°C
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UniProt
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A8G
mutant exhibits activity only for a combination of UTP and glucose 1-phosphate, similar to wild-type
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Maeda, K.; Narikawa, R.; Ikeuchi, M.
CugP is a novel ubiquitous non-GalU-type bacterial UDP-glucose pyrophosphorylase found in cyanobacteria
J. Bacteriol.
196
2348-2354
2014
Synechocystis sp. (P74285), Synechocystis sp.
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