Information on EC 2.7.7.82 - CMP-N,N'-diacetyllegionaminic acid synthase

for references in articles please use BRENDA:EC2.7.7.82
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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.7.7.82
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RECOMMENDED NAME
GeneOntology No.
CMP-N,N'-diacetyllegionaminic acid synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CTP + N,N'-diacetyllegionaminate = CMP-N,N'-diacetyllegionaminate + diphosphate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
CMP-legionaminate biosynthesis I
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CMP-legionaminate biosynthesis II
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Amino sugar and nucleotide sugar metabolism
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SYSTEMATIC NAME
IUBMB Comments
CTP:N,N'-diacetyllegionaminate cytidylyltransferase
Isolated from the bacteria Legionella pneumophila and Campylobacter jejuni. Involved in biosynthesis of legionaminic acid, a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates which may include lipopolysaccharide (LPS), capsular polysaccharide, pili and flagella.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CTP + N,N'-diacetyllegionaminic acid
CMP-N,N'-diacetyllegionaminic acid + diphosphate
show the reaction diagram
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
immobilized metal ion affinity chromatography (Ni2+)
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
His-tagged protein expressed in Escherichia coli
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His-tagged protein expressed in Escherichia coli BL21(DE3)
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Show AA Sequence (132 entries)
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