involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
knocking down CDS1 results in the formation of giant or supersized lipid droplets in cultured cells. Depleting CDS2 in 3T3-L1 preadipocytes has a moderate inhibitory effect on adipocyte differentiation. Only a small number of phosphatidate species are increased upon depleting CDS2, the amount of phosphatidate in the endoplasmic reticulum is dramatically increased upon knocking down CDS2, overview. The changes in phosphatidate level and localization may underlie the formation of giant lipid droplets as well as the block in adipogenesis in CDS-deficient cells
knocking down CDS1 results in the formation of giant or supersized lipid droplets in cultured cells. Depleting CDS1 almost completely blocked the differentiation of 3T3-L1 preadipocytes. The levels of many phosphatidate species are significantly increased upon knocking down CDS1, the amount of phosphatidate in the endoplasmic reticulum is dramatically increased upon knocking down CDS1, overview. The changes in phosphatidate level and localization may underlie the formation of giant lipid droplets as well as the block in adipogenesis in CDS-deficient cells
knocking down either isoform CDS1 or isoform CDS2 results in the formation of giant or supersized lipid droplets in cultured cells. Depleting CDS2 has a moderate inhibitory effect on adipocyte differentiation. Only a small number of phosphatidic acid species are increased upon depleting CDS2. The amount of phosphatidic acid in the endoplasmic reticulum is dramatically increased upon knocking down CDS1 or CDS2
CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development, role of CDP-diacylglycerol in lipid storage in mammals. The expansion of lipid droplets and the differentiation of preadipocytes are two important aspects of mammalian lipid storage, CDS1 and CDS2 are important regulators of lipid storage
knocking down either isoform CDS1 or isoform CDS2 results in the formation of giant or supersized lipid droplets in cultured cells. Depleting CDS1 almost completely blocks the differentiation of 3T3-L1 preadipocytes. The levels of many phosphatidic acid species are significantly increased upon knocking down CDS1. The amount of phosphatidic acid in the endoplasmic reticulum is dramatically increased upon knocking down CDS1 or CDS2
CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development, role of CDP-diacylglycerol in lipid storage in mammals. The expansion of lipid droplets and the differentiation of preadipocytes are two important aspects of mammalian lipid storage, CDS1 and CDS2 are important regulators of lipid storage
transient siRNA knockdown of CDS1 in 3T3-L1 cells downregulates CDS2 by 90%. Knocking down CDS2 results in the formation of giant or supersized lipid droplets in cultured cells
transient siRNA knockdown of CDS1 in 3T3-L1 cells downregulates CDS2 by 90%. Knocking down CDS2 results in the formation of giant or supersized lipid droplets in cultured cells
transient siRNA knockdown of CDS1 in 3T3-L1 cells downregulates CDS1 by 48%. Knocking down CDS1 results in the formation of giant or supersized lipid droplets in cultured cells
transient siRNA knockdown of CDS1 in 3T3-L1 cells downregulates CDS1 by 48%. Knocking down CDS1 results in the formation of giant or supersized lipid droplets in cultured cells