Reference on EC 2.7.7.38 - 3-deoxy-manno-octulosonate cytidylyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wylie, J.L.; Iliffe, E.R.; Wang, L.L.; McClarty, G.
Identification, characterization, and developmental regulation of Chlamydia trachomatis 3-deoxy-D-manno-octulosonate (KDO)-8-phosphate synthetase and CMP-KDO synthetase
Infect. Immun.
65
1527-1530
1997
Chlamydia trachomatis, Chlamydia trachomatis (P0CD75)
Ghalambor, M.A.; Heath, E.H.
The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. IV. Purification and properties of cytidine monophosphate 3-deoxy-D-manno-octulosonate synthetase
J. Biol. Chem.
241
3216-3221
1966
Escherichia coli, Escherichia coli 0111-B4
Ray, P.H.; Benedict, C.D.; Grasmuk, H.
Purification and characterization of cytidine 5-triphosphate:cytidine 5-monophosphate-3-deoxy-D-manno-octulosonate cytidylyltransferase
J. Bacteriol.
145
1273-1280
1981
Escherichia coli, Escherichia coli B / ATCC 11303
Ray, P.H.; Benedict, C.D.
CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase)
Methods Enzymol.
83
535-540
1982
Escherichia coli, Escherichia coli B / ATCC 11303
Claesson, A.; Luthman, K.; Gustafsson, K.; Bondesson, G.
A 2-deoxy analogue of KDO as the first inhibitor of the enzyme CMP-KDO synthetase
Biochem. Biophys. Res. Commun.
143
1063-1068
1987
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli D21, Salmonella enterica subsp. enterica serovar Typhimurium SL 1102
Rosenow, C.; Roberts, I.S.; Jann, K.
Isolation from recombinant Escherichia coli and characterization of CMP-Kdo synthetase, involved in the expression of the capsular K5 polysaccharide (K-CKS)
FEMS Microbiol. Lett.
125
159-164
1995
Escherichia coli
Sugai, T.; Lin, C.H.; Shen, G.J.; Wong, C.H.
CMP-KDO synthetase: overproduction and application to the synthesis of CMP-KDO and analogs
Bioorg. Med. Chem.
3
313-320
1995
Escherichia coli
Jelakovic, S.; Jann, K.; Schulz, G.E.
The three-dimensional structure of capsule-specific CMP: 2-keto-3-deoxy-manno-octonic acid synthetase from Escherichia coli
FEBS Lett.
391
157-161
1996
Escherichia coli
Royo, J.; Gomez, E.; Hueros, G.
A maize homologue of the bacterial CMP-3-deoxy-D-manno-2-octulosonate (KDO) synthetases. Similar pathways operate in plants and bacteria for the activation of KDO prior to its incorporation into outer cellular envelopes
J. Biol. Chem.
275
24993-24999
2000
Zea mays
Royo, J.; Gomez, E.; Hueros, G.
CMP-KDO synthetase. A plant gene borrowed from Gram-negative eubacteria
Trends Genet.
16
432-433
2000
Aggregatibacter actinomycetemcomitans, Aquifex pyrophilus, Arabidopsis thaliana, Chlamydia pneumoniae, Chlamydia trachomatis, Chlorobaculum tepidum, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Homo sapiens, Solanum lycopersicum, Neisseria meningitidis, no activity in Caenorhabditis elegans, no activity in Saccharomyces cerevisiae, no activity in Drosophila melanogaster, Yersinia pestis, Rickettsia prowazekii, Zea mays, Vibrio cholerae serotype O1
Jelakovic, S.; Schulz, G.E.
The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogs
J. Mol. Biol.
312
143-155
2001
Escherichia coli, Escherichia coli (P42216)
Tzeng, Y.L.; Datta, A.; Strole, C.; Kolli, V.S.; Birck, M.R.; Taylor, W.P.; Carlson, R.W.; Woodard, R.W.; Stephens, D.S.
KpsF is the arabinose-5-phosphate isomerase required for 3-deoxy-D-manno-octulosonic acid biosynthesis and for both lipooligosaccharide assembly and capsular polysaccharide expression in Neisseria meningitidis
J. Biol. Chem.
277
24103-24113
2002
Neisseria meningitidis
Bravo, I.G.; Reglero, A.
The cytidyltransferases family: Properties, kinetics, genomic and phylogeny
Recent Res. Devel. Biochem.
4
224-254
2003
Aquifex aeolicus, Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia trachomatis, Escherichia coli, Escherichia coli (P42216), Haemophilus influenzae, Helicobacter pylori, Neisseria meningitidis, Neisseria meningitidis (Q9K0D6), Pasteurella multocida, Pseudomonas aeruginosa, Rickettsia prowazekii, Salmonella enterica subsp. enterica serovar Typhimurium, Zea mays, Zea mays (Q9M4D3), Zea mays (Q9M4G3), Rickettsia conorii (Q92I96), Sinorhizobium meliloti (Q92SX6), Mesorhizobium loti (Q98BN3), Caulobacter vibrioides (Q9A4A3), Arabidopsis thaliana (Q9C920), Vibrio cholerae (Q9KQX2), Xylella fastidiosa (Q9PB46), Neisseria meningitidis MC58 (Q9K0D6)
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Ku, M.J.; Yoon, H.J.; Ahn, H.J.; Kim, H.W.; Baek, S.H.; Suh, S.W.
Crystallization and preliminary X-ray crystallographic studies of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae
Acta Crystallogr. Sect. D
59
180-182
2003
Haemophilus influenzae
Kondo, K.; Doi, H.; Adachi, H.; Nishimura, Y.
Synergistic effect of CMP/KDO synthase inhibitors with antimicrobial agents on inhibition of production and release of vero toxin by enterohaemorrhagic Escherichia coli O157:H7
Bioorg. Med. Chem. Lett.
14
467-470
2004
Escherichia coli
Yoon, H.J.; Ku, M.J.; Mikami, B.; Suh, S.W.
Structure of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae complexed with the substrate 3-deoxy-manno-octulosonate in the beta-configuration
Acta Crystallogr. Sect. D
64
1292-1294
2008
Haemophilus influenzae (P44490), Haemophilus influenzae
Yi, L.; Velasquez, M.S.; Holler, T.P.; Woodard, R.W.
A simple assay for 3-deoxy-D-manno-octulosonate cytidylyltransferase and its use as a pathway screen
Anal. Biochem.
416
152-158
2011
Escherichia coli
Kobayashi, M.; Kouzu, N.; Inami, A.; Toyooka, K.; Konishi, Y.; Matsuoka, K.; Matoh, T.
Characterization of Arabidopsis CTP:3-deoxy-D-manno-2-octulosonate cytidylyltransferase (CMP-KDO synthetase), the enzyme that activates KDO during rhamnogalacturonan II biosynthesis
Plant Cell Physiol.
52
1832-1843
2011
Arabidopsis thaliana (Q9C920)
Schmidt, H.; Mesters, J.; Wu, J.; Woodard, R.; Hilgenfeld, R.; Mamat, U.
Evidence for a two-metal-ion mechanism in the cytidyltransferase KdsB, an enzyme involved in lipopolysaccharide biosynthesis
PLoS ONE
6
e23231
2011
Aquifex aeolicus (O66914), Aquifex aeolicus
Wen, L.; Zheng, Y.; Li, T.; Wang, P.G.
Enzymatic synthesis of 3-deoxy-D-manno-octulosonic acid (KDO) and its application for LPS assembly
Bioorg. Med. Chem. Lett.
26
2825-2828
2016
Escherichia coli (P04951)
Nilsson, I.; Grove, K.; Dovala, D.; Uehara, T.; Lapointe, G.; Six, D.A.
Molecular characterization and verification of azido-3,8-dideoxy-D-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide
J. Biol. Chem.
292
19840-19848
2017
Escherichia coli (P04951)
Ahmad, S.; Raza, S.; Abro, A.; Liedl, K.R.; Azam, S.S.
Toward novel inhibitors against KdsB a highly specific and selective broad-spectrum bacterial enzyme
J. Biomol. Struct. Dyn.
37
1326-1345
2019
Acinetobacter baumannii (A3M4Z0), Acinetobacter baumannii ATCC 17978 (A3M4Z0)
Kim, S.; Jo, S.; Kim, M.S.; Shin, D.H.
A study of Rose Bengal against a 2-keto-3-deoxy-D-manno-octulosonate cytidylyltransferase as an antibiotic candidate
J. Enzyme Inhib. Med. Chem.
35
1414-1421
2020
Burkholderia thailandensis, Pseudomonas aeruginosa (A0A0C7D0B2), Pseudomonas aeruginosa, Chlamydia psittaci (A0A2D2D9V4), Chlamydia psittaci, Burkholderia pseudomallei (Q63WL5), Burkholderia pseudomallei, Burkholderia pseudomallei K96243 (Q63WL5)
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