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BRENDA support

Information on EC 2.7.7.31 - DNA nucleotidylexotransferase

for references in articles please use BRENDA:EC2.7.7.31

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IUBMB Comments

Catalyses template-independent extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. The nucleoside may be ribo- or 2'-deoxyribo-.

The enzyme appears in viruses and cellular organisms

Synonyms
terminal deoxynucleotidyl transferase, terminal deoxynucleotidyl transferase (tdt), deoxynucleotidyl transferase, terminal deoxynucleotidyltransferase, terminal deoxynucleotide transferase, terminal deoxyribonucleotidyl transferase, rep75, terminal deoxyribonucleotidyltransferase, deoxynucleotidyl terminal transferase, dna nucleotidylexotransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn = diphosphate + DNAn+1
show the reaction diagram