Information on EC 2.7.7.27 - glucose-1-phosphate adenylyltransferase

-

r

P55228, P55229, P55230, P55231, Q9SIK1

-

-

r

Escherichia coli

-

671752, 674337

-

r

Glycine max

-

-

r

Hordeum vulgare

-

-

r

Malus domestica

-

-

r

Oryza sativa

P15280, Q688T8, Q69T99, Q6AVT2, Q7G065

-

676561

-

r

P15280, Q688T8, Q69T99, Q6AVT2, Q7G065

first committed step of starch biosynthesis in higher plants, identification of identify AGP isoforms essential for this biosynthetic process in sink and source tissues of rice plants

676561

-

r

Solanum lycopersicum

-

-

r

Solanum tuberosum

-

671807, 673678, 676354, 693217, 694734

-

r

-

substrate binding structure and kinetics, regulation of wild-type and mutant enzymes, mapping the polymorphic sites important in altered allosteric properties, overview

694734

-

r

-

the small subunit displays both catalytic and regulatory properties, the large subunit possesses catalytic and regulatory properties only when assembled with small subunit, the net properties of the heterotetrameric enzyme is a product of subunit synergy, overview

693217

-

r

Sorghum sp.

-

-

r

Spinacia oleracea

-

-

r

Triticum aestivum

-

-

r

Zea mays

-

693447

-

?

-

694714, 694734, 694760

-

r

-

AGPase, a key regulatory enzyme in starch biosynthesis, is highly regulated, effects of substrates, detailed overview

694714

-

r

-

the enzyme is required for starch biosynthesis, while Tdy1 is not required, although tdy1-R mutant leaves retain large amounts of starch on prolonged dark treatment, consistent with a defect in starch catabolism, overview

693447

-

?

-

substrate binding structure and kinetics, regulation of wild-type and mutant enzymes, mapping the polymorphic sites important in altered allosteric properties, overview

694734

-

r

ATP + alpha-D-glucose 1-phosphate

diphosphate + ADP-glucose

Aeromonas caviae

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Aeromonas hydrophila

-

-

r

-

specific for ATP

-

r

-

not: ITP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

not: dTTP, XTP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Agrobacterium tumefaciens

r

-

-

?

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Allochromatium vinosum

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Anabaena sp.

-

643123, 643139, 643159, 643161

-

643149, 643164

-

r

-

-

P30521

-

-

?

-

-

?

-

one of the main regulatory steps in starch biosynthesis in plants

643149

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

-

-

?

-

662449, 663026

-

?

P55228, P55229

-

-

?

P55228, P55229, P55230, P55231, Q9SIK1

-

-

?

-

no substrate are alpha-D-mannose 1-phosphate or alpha-D-galactose 1-phosphate

643136

-

?

-

key regulatory enzyme of starch biosynthesis

643166

-

643166

?

-

different large subunit isoforms allow the enzyme to be efficiently regulated according to the metabolic situation and the starch necessities of a tissue. In source tissues, ADP-glucose diphosphorylase would be finely regulated by the 3-phosphoglycerate/phosphate ratio, whereas in sink tissues, the enzyme would be dependent on the availability of substrates for starch synthesis

662449

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Arachis hypogaea

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Auxenochlorella pyrenoidosa

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

-

-

r

-

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Blastochloris viridis

-

-

r

-

-

Chlamydomonas reinhardtii

r

-

643122

-

?

-

-

?

-

-

?

-

-

r

-

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643122

-

?

Q42702, Q9LLL6

key regulatory enzyme of starch biosynthesis

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Chlorella fusca

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Chlorella vulgaris

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

Chlorobaculum thiosulfatiphilum

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Clostridium pasteurianum

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Edwardsiella tarda

-

specific for ATP

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Escherichia aurescens

-

643142

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

-

643114, 643126, 643128, 643129

-

?

-

643146

-

643146

?

-

643148

-

643148

?

-

-

?

-

-

?

P0A6V1

-

674737

-

?

-

706180, 721757, 739494, 739606

-

?

-

643127

-

643127

r

-

-

r

-

-

r

-

-

r

-

-

r

-

-

r

-

-

substrate binding studies: 1 mol glucose 1-phosphate per mol subunit, 4 mol ADP-glucose per mol tetrameric enzyme

-

?, r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643114

-

key regulatory enzyme of starch biosynthesis

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Escherichia coli glgC

P0A6V1

-

-

Escherichia coli SG14

-

substrate binding studies: 1 mol glucose 1-phosphate per mol subunit, 4 mol ADP-glucose per mol tetrameric enzyme

-

?, r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Geobacillus stearothermophilus

r

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Hafnia alvei

-

specific for ATP

-

r

-

not: ITP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

not: dTTP, XTP

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

r

-

-

r

-

-

r

-

-

?

O04896, P30524, P55238

-

-

?

-

-

-

-

?

P30524

first step of starch biosynthesis

643113

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643168

-

Ipomoea batatas

-

643163

-

?

-

-

?

-

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Klebsiella pneumoniae

-

specific for ATP

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

Micrococcus luteus

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Mycobacterium smegmatis

-

specific for ATP

-

r

-

specific for ADP-glucose in the reverse direction

-

r

-

no substrate is UTP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Nitrosomonas europaea

Q82T88

the catalytic efficiency for ATP is not dependent upon the divalent metal ion

722552

-

r

Nostoc sp.

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

-

-

-

-

-

-

663026, 663092, 706180, 739279

-

?

-

-

r

-

-

r

-

-

?

P93430

-

-

?

O23809, P15280, Q9ARH9

-

-

?

Q9ARH9

-

643169

-

?

-

first step of starch biosynthesis

643156

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643157, 643158

-

P15280

key regulatory enzyme of starch biosynthesis

643114

-

?

-

first committed step in synthesis of ADP-glucose

-

?

-

the reduction of cytosolic ADP-glucose pyrophosphorylase activity in shrunken endosperm did not inhibit granule initiation but severely restrained the subsequent enlargement of granules

663092

-

?

Ostreococcus tauri

-

704593

-

?

Persea americana

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Phaeospirillum fulvum

-

-

r

-

-

Phaeospirillum molischianum

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

?

-

-

r

Q43815, Q43816, Q43819

-

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Rhodobacter capsulatus

-

-

?

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Rhodobacter gelatinosa

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Rhodobacter globiformis

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Rhodobacter sphaeroides

Q9RNH7

-

643161

-

-

?

-

-

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Rhodoblastus acidophilus

-

-

r

-

-

r

-

-

?

Rhodocyclus purpureus

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Rhodocyclus tenuis

-

-

?

-

-

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Rhodomicrobium vannielii

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Rhodopila globiformis

-

-

r

-

-

Rhodopseudomonas palustris

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Rhodospirillum rubrum

-

-

?

-

-

r

-

-

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

Rhodospirillum rubrum ICPB 2204

-

?

-

-

r

Rubrivivax gelatinosus

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Salmonella enterica subsp. enterica serovar Enteritidis

r

-

specific for ATP

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Salmonella enterica subsp. enterica serovar Typhimurium

r

-

643142

-

-

r

-

-

r

-

-

r

-

-

r

-

-

?

-

specific for ATP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

Salmonella enterica subsp. enterica serovar Typhimurium LT2

r

-

-

r

Serratia liquefaciens

-

-

r

-

specific for ATP

-

r

-

specific for ATP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

?

-

-

r

-

specific for ATP

-

r

-

specific for ATP

-

r

-

not: ITP

-

r

-

not: ITP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

not: dTTP, XTP

-

r

-

not: dTTP, XTP

-

r

-

ADP-glucose synthesis at 50%, strain 274 or 75%, strain 15365 the rate of pyrophosphorolysis

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Shigella dysenteriae

-

-

r

-

specific for ATP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

-

r

O04924, P93229, P93230, Q42882

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

-

-

-

-

-

?

-

-

?

-

643145

-

?

-

643147

-

643147

?

-

661594, 663026, 663126, 663141, 676387, 693418, 702704, 706407, 737552

-

?

-

643115

-

643115

r

-

-

r

-

-

r

-

-

-

-

?

P23509, P55242, P55243, Q00081

-

-

?

Q00081

-

706322, 737860, 739280

-

?

Q00081 and P23509

-

738238

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

643145

-

?

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643157

-

ADP-glucose pyrophosphorylase catalyzes the first committed and rate-limiting step in starch biosynthesis

661594

-

?

-

first committed step in synthesis of ADP-glucose

-

?

-

rate-limiting step in starch biosynthesis

663141

-

?

-

rate-limiting step in starch synthesis, both subunits are involved in the allosteric regulation of AGPase

663126

-

?

-

enzyme consists of two regulatory large subunits and two catalytic small subunits. Allosterism and catalysis are the products of an interplay between the regulatory large subunits and the catalytic small subunits that result in a synergistic response to the allosteric effectors and substrates

661773

-

?

Solanum tuberosum LS1

Q00081

-

-

?

Solanum tuberosum LS2

P55242

-

-

?

Solanum tuberosum LS3

P55243

-

-

?

Solanum tuberosum SS

P23509

-

-

Sorghum sp.

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

?

-

-

r

-

-

r

-

-

r

-

-

r

-

-

r

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

Streptococcus mutans ATCC 25175

-

?

Streptococcus mutans

M9TIK1 and M9TG57

-

739100

-

?

M9TIK1 and M9TG57

-

739100

-

?

Streptomyces coelicolor

enzyme is specific for ATP and reaches similar activities in the directions of ADP-glucose synthesis or diphosphorolysis

Streptomyces coelicolor A3(2)

-

r

enzyme is specific for ATP and reaches similar activities in the directions of ADP-glucose synthesis or diphosphorolysis

-

r

Synechococcus sp.

-

643137

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

Synechococcus sp. PCC6301

-

?

-

-

?

-

first committed step in synthesis of ADP-glucose

-

?

Synechocystis sp.

-

643123, 663026

-

?

-

-

r

-

-

P52415

-

643124, 643151

-

?

-

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

-

?

Tetradesmus obliquus

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

Thermus caldophilus

-

not: ITP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

no substrate is UTP

-

Thermus caldophilus GK-24

r

-

not: ITP

-

r

-

no substrate are GTP, dATP, CTP

-

r

-

no substrate is UTP

-

r

-

-

-

-

-

?

-

-

r

-

-

?

-

-

?

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

first committed step in synthesis of ADP-glucose

Vigna radiata var. radiata

-

?

-

-

?

-

-

?

-

-

?

-

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

-

-

-

-

-

-

?

-

-

?

-

643154, 663026, 663141, 706326, 706334

-

?

-

643120

-

643120

r

-

-

r

-

-

r

Q941P2, Q947B9, Q947C0

-

-

?

Q941P2, Q947B9, Q947C0

-

643169

-

?

-

706292

-

?

P55241

-

706322

-

?

Q947C0 and P55241

-

737552

-

?

-

737555

-

?

-

specific for ATP

-

r

-

not: TTP

-

r

-

no substrate is UTP

-

r

-

first unique reaction in synthesis of alpha-1,4-glucosidic linkage

-

r

-

one of the main regulatory steps in starch biosynthesis in plants

-

r

-

major regulated step in the bacterial glycogen biosynthesis pathway

-

r

-

key regulatory enzyme of starch biosynthesis

643157, 643158

-

key regulatory enzyme of starch biosynthesis

643154

-

?

-

key regulatory enzyme of starch biosynthesis

-

r

-

first committed step in synthesis of ADP-glucose

-

?

-

rate-limiting step in starch biosynthesis

663141

-

?

ATP + alpha-D-glucose-1-phosphate

ADP-D-glucose + diphosphate

Nicotiana tabacum

-

694709

-

r

-

AGP plays a crucial role in the morphogenesis of petal limbs in Xanthi through the synthesis of starch, which is the main carbohydrate source for expansion growth of petal limbs, in sepal tisues, overview

694709

-

r

diphosphate + ADP

ATP + alpha-D-glucose

Escherichia coli

-

671752

-

r

Solanum tuberosum

-

671807, 673678

-

r

diphosphate + ADP-glucose

ATP + alpha-D-glucose 1-phosphate

Solanum lycopersicum

Q15I66

-

721522

-

r

Streptomyces coelicolor

enzyme reaches similar activities in the directions of ADP-glucose synthesis or diphosphorolysis

Streptomyces coelicolor A3(2)

-

r

enzyme reaches similar activities in the directions of ADP-glucose synthesis or diphosphorolysis

-

r

additional information

?

-

Arabidopsis thaliana

P55228

ADP-Glc PPase catalyzes the first committed step in starch biosynthesis

-

P55229

ADP-Glc PPase catalyzes the first committed step in starch biosynthesis

-

P55230

ADP-Glc PPase catalyzes the first committed step in starch biosynthesis

-

P55231

ADP-Glc PPase catalyzes the first committed step in starch biosynthesis

-

Q9SIK1

ADP-Glc PPase catalyzes the first committed step in starch biosynthesis

-

ADP-glucose pyrophosphorylase catalyzes a rate-limiting step in starch synthesis

Chlamydomonas reinhardtii

-

-

ADP-glucose pyrophosphorylase catalyzes a rate-limiting step in starch synthesis

Escherichia coli K-12 618

-

Escherichia coli

-

identification of regions critically affecting kinetics and allosteric regulation of the ADP-glucose pyrophosphorylase, structure-function analysis, homology modelling, overview

674337

-

enzyme displays a regulatory mechanism where the interaction with the allosteric activator triggers conformational changes at the level of loops containing residues Trp113 and Gln74

721757

-

Escherichia coli K-12

-

AGPase plays a key role in regulating starch biosynthesis in cereal seeds and is likely the most important determinant of seed strength

694640

-

-

AGPase plays a key role in regulating starch biosynthesis in cereal seeds and is likely the most important determinant of seed strength

694640

-

Fragaria x ananassa

-

a key enzyme in starch biosynthesis, its expression is regulated at both the transcriptional and post-transcriptional levels during fruit ripening, overview

692432

-

Hordeum vulgare

-

ADP-glucose pyrophosphorylase catalyzes a rate-limiting step in starch synthesis

-

Nitrosomonas europaea

-

enzyme is able to accept UTP, CTP, dTTP and GTP with catalytic efficiencies below 1% of that with ATP

722552

-

Q82T88

enzyme is able to accept UTP, CTP, dTTP and GTP with catalytic efficiencies below 1% of that with ATP

722552

-

Oryza sativa

-

ADP-glucose pyrophosphorylase catalyzes a rate-limiting step in starch synthesis