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Adenocarcinoma
MAGI-2 Is a Sensitive and Specific Marker of Prostatic Adenocarcinoma: ?A Comparison With AMACR.
Adenoma
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) and guanylate kinase 1 (GUK1) are differentially expressed in GH-secreting adenomas.
Adenomatous Polyposis Coli
Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.
Adenomatous Polyposis Coli
Human homologue of the Drosophila discs large tumor suppressor protein forms an oligomer in solution. Identification of the self-association site.
Adenomatous Polyposis Coli
Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.
Adenomatous Polyposis Coli
Structure of the human discs large 1 PDZ2- adenomatous polyposis coli cytoskeletal polarity complex: insight into peptide engagement and PDZ clustering.
Alzheimer Disease
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
Anemia
Iron deficiency anemia in cyclic GMP kinase knockout mice.
Anemia, Iron-Deficiency
Iron deficiency anemia in cyclic GMP kinase knockout mice.
Ankylosis
A recessive mutation leading to vertebral ankylosis in zebrafish is associated with amino acid alterations in the homologue of the human membrane-associated guanylate kinase DLG3.
Atherosclerosis
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis.
Brain Diseases
Genes of early-onset epileptic encephalopathies: from genotype to phenotype.
Brain Ischemia
Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor.
Breast Neoplasms
HDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cells.
Breast Neoplasms
Loss of the tight junction MAGUK ZO-1 in breast cancer: relationship to glandular differentiation and loss of heterozygosity.
Carcinogenesis
Loss of the tight junction MAGUK ZO-1 in breast cancer: relationship to glandular differentiation and loss of heterozygosity.
Carcinoma
Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma.
Carcinoma, Hepatocellular
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Carcinoma, Hepatocellular
MAGI1 inhibits cancer cell migration and invasion of hepatocellular carcinoma via regulating PTEN.
Carcinoma, Renal Cell
Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma.
Cleft Palate
A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia.
Crohn Disease
Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD.
Crohn Disease
The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network.
Deafness
Protein 4.1 expression in the developing hair cells of the mouse inner ear.
Dyskinesias
A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia.
Epilepsy
Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11.
Glioma
A guanylate kinase/HSV-1 thymidine kinase fusion protein enhances prodrug-mediated cell killing.
Glioma
MAGI1 Inhibits the Proliferation, Migration and Invasion of Glioma Cells.
Glioma
MAGI3 negatively regulates Wnt/?-catenin signaling and suppresses malignant phenotypes of glioma cells.
Glioma
MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression.
Herpes Zoster
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
Herpes Zoster
Structural requirements for calmodulin binding to membrane-associated guanylate kinase homologs.
Herpes Zoster
Synaptic State-Dependent Functional Interplay between Postsynaptic Density-95 and Synapse-Associated Protein 102.
Hydronephrosis
Decreased apoptosis and persistence of the common nephric duct during the development of an aberrant vesicoureteral junction in Dlg1 gene-targeted mice.
Infections
Genome-Scale Metabolic Model of Infection with SARS-CoV-2 Mutants Confirms Guanylate Kinase as Robust Potential Antiviral Target.
Infections
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy.
Inflammatory Bowel Diseases
The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network.
Intellectual Disability
Mechanisms of MAGUK-mediated cellular junctional complex organization.
Intellectual Disability
Polymorphisms in the DLG3 Gene is not Associated with Non-Syndromic Mental Retardation in the Chinese Han Population of Qin-Ba Mountain.
Intellectual Disability
Psychopathology and cognitive performance in individuals with membrane-associated guanylate kinase mutations: a functional network phenotyping study.
Intellectual Disability
SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus.
Intellectual Disability
Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Intellectual Disability
Synaptopathies: diseases of the synaptome.
Leukemia
Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes.
Leukemia, T-Cell
Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes.
Lymphoma
Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Lymphoma
Crystallization and preliminary X-ray crystallographic studies of the CARD domain of human CARMA1.
Lymphoma
Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappaB activation by the adapter protein ADAP.
Lymphoma
Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma.
Lymphoma
Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.
Lymphoma
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation.
Lymphoma, B-Cell
Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Lymphoma, B-Cell
Cloning, characterization, and modeling of mouse and human guanylate kinases.
Lymphoma, B-Cell
MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells.
Lymphoma, B-Cell
Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma.
Lymphoma, B-Cell
Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.
Lymphoma, B-Cell
Protease activity of MALT1: a mystery unravelled.
Lymphoma, B-Cell, Marginal Zone
Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Lymphoma, B-Cell, Marginal Zone
Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.
Malaria
Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.
Melanoma
DLG2, but not TMEM229B, GPNMB, and ITGA8 polymorphism, is associated with Parkinson's disease in a Taiwanese population.
Mitochondrial Diseases
Progress in pathogenesis of proteinuria.
Myocardial Infarction
Weighted gene co?expression network analysis in identification of key genes and networks for ischemic?reperfusion remodeling myocardium.
Neoplasm Metastasis
CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I (HTLV-I) transformed cells and adult T-cell leukemia (ATL) cells: possible involvement of CADM1 in pathogenesis of ATL.
Neoplasm Metastasis
CASK regulates Notch pathway and functions as a tumor promoter in pancreatic cancer.
Neoplasm Metastasis
Downregulation of MAGI1 Associates with Poor Prognosis of Hepatocellular Carcinoma.
Neoplasm Metastasis
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) and guanylate kinase 1 (GUK1) are differentially expressed in GH-secreting adenomas.
Neoplasm Metastasis
Silencing Of MAGI1 Promotes The Proliferation And Inhibits Apoptosis Of Glioma Cells Via The Wnt/?-Catenin And PTEN/AKT Signaling Pathways.
Neoplasm Metastasis
[Knock-down of CARMA1 in K562 cells inhibits the invasion and metastasis of K562 cells].
Neoplasms
?-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation.
Neoplasms
A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells.
Neoplasms
A major palmitoylated membrane protein of human erythrocytes shows homology to yeast guanylate kinase and to the product of a Drosophila tumor suppressor gene.
Neoplasms
A New Story of the Three Magi: Scaffolding Proteins and lncRNA Suppressors of Cancer.
Neoplasms
Abnormal development of urogenital organs in Dlgh1-deficient mice.
Neoplasms
ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.
Neoplasms
Camguk, Lin-2, and CASK: novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains.
Neoplasms
CARMA3 is overexpressed in human glioma and promotes cell invasion through MMP9 regulation in A172 cell line.
Neoplasms
CARMA3 Transcriptional Regulation of STMN1 by NF-?B Promotes Renal Cell Carcinoma Proliferation and Invasion.
Neoplasms
CASK Deletion in Intestinal Epithelia Causes Mislocalization of LIN7C and the DLG1/Scrib Polarity Complex without Affecting Cell Polarity.
Neoplasms
cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus.
Neoplasms
Characterization of a novel human cell-cycle-regulated homologue of Drosophila dlg1.
Neoplasms
Degradation of hDlg and MAGIs by human papillomavirus E6 is E6-AP-independent.
Neoplasms
Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.
Neoplasms
Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.
Neoplasms
DLG1: chromosome location of the closest human homologue of the Drosophila discs large tumor suppressor gene.
Neoplasms
DLGH1 Is a Negative Regulator of T-Lymphocyte Proliferation.
Neoplasms
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Neoplasms
HDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cells.
Neoplasms
Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes.
Neoplasms
Human homologue of the Drosophila discs large tumor suppressor protein forms an oligomer in solution. Identification of the self-association site.
Neoplasms
Identification of MAGI1 as a tumor-suppressor protein induced by cyclooxygenase-2 inhibitors in colorectal cancer cells.
Neoplasms
Identification of the mouse homologue of human discs large and rat SAP97 genes.
Neoplasms
Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.
Neoplasms
Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis.
Neoplasms
Lano, a novel LAP protein directly connected to MAGUK proteins in epithelial cells.
Neoplasms
Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cells.
Neoplasms
MAGI-2 scaffold protein is critical for kidney barrier function.
Neoplasms
MAGI1 Inhibits the Proliferation, Migration and Invasion of Glioma Cells.
Neoplasms
MAGI1, a New Potential Tumor Suppressor Gene in Estrogen Receptor Positive Breast Cancer.
Neoplasms
Mechanisms of MAGUK-mediated cellular junctional complex organization.
Neoplasms
Membrane palmitoylated protein 3 promotes hepatocellular carcinoma cell migration and invasion via up-regulating matrix metalloproteinase 1.
Neoplasms
Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions.
Neoplasms
Methylation-mediated silencing of Dlg5 facilitates bladder cancer metastasis.
Neoplasms
Molecular and biological characterization of a zonula occludens-1 homologue in Hydra vulgaris, named HZO-1.
Neoplasms
Silencing Of MAGI1 Promotes The Proliferation And Inhibits Apoptosis Of Glioma Cells Via The Wnt/?-Catenin And PTEN/AKT Signaling Pathways.
Neoplasms
Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.
Neoplasms
Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein.
Neoplasms
The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions.
Neoplasms
The mouse guanylate kinase double mutant E72Q/D103N is a functional adenylate kinase.
Neoplasms
The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration.
Neoplasms
The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
Neoplasms
The PDZ protein MPP2 interacts with c-Src in epithelial cells.
Neoplasms
VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain.
Neoplasms
Weighted gene co?expression network analysis in identification of key genes and networks for ischemic?reperfusion remodeling myocardium.
Neoplasms
ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin.
Nephrotic Syndrome
Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2.
Nephrotic Syndrome
MAGI-2 and scaffold proteins in glomerulopathy.
Neurodegenerative Diseases
MAGUK proteins: new targets for pharmacological intervention in the glutamatergic synapse.
Parkinson Disease
A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons.
Pituitary Neoplasms
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) and guanylate kinase 1 (GUK1) are differentially expressed in GH-secreting adenomas.
Prostatic Neoplasms
MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Prostatic Neoplasms
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI-2) in prostate cancer: an immunohistochemical study.
Proteinuria
Progress in pathogenesis of proteinuria.
Sarcoma
Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.
Seizures
Intrinsic epileptogenicity of dysplastic cortex: Converging data from experimental models and human patients.
Starvation
Expression of kinA and kinB of Bacillus subtilis, Necessary for Sporulation Initiation, Is under Positive Stringent Transcription Control.
Starvation
Genetic diversity and population structure of food-borne Staphylococcus carnosus strains.
Starvation
Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors.
Starvation
Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp.
Status Epilepticus
Intrinsic epileptogenicity of dysplastic cortex: Converging data from experimental models and human patients.
Stomach Neoplasms
ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.
Stomach Neoplasms
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Stomach Neoplasms
MAGI1 inhibits migration and invasion via blocking MAPK/ERK signaling pathway in gastric cancer.
Stroke
Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor.
Tuberculosis
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy.
Tuberculosis
Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase.
Urinary Bladder Neoplasms
Long noncoding RNA MAGI2-AS3 inhibits bladder cancer progression through MAGI2/PTEN/epithelial-mesenchymal transition (EMT) axis.
Uterine Cervical Neoplasms
Reduced MAGI3 level by HPV18E6 contributes to Wnt/?-catenin signaling activation and cervical cancer progression.
Vaccinia
Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.
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2.7.4.8 guanylate kinase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
