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IUBMB Comments The enzyme, found in plants and animals, is specific for CTP as phosphate donor. It does not use farnesol as substrate (cf . EC 2.7.1.216 , farnesol kinase).
The enzyme appears in viruses and cellular organisms
Synonyms farnesyl phosphate kinase, more
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CTP + (2E,6E)-farnesyl phosphate = CDP + (2E,6E)-farnesyl diphosphate
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MetaCyc
farnesylcysteine salvage pathway
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CTP:(2E,6E)-farnesyl-phosphate phosphotransferase
The enzyme, found in plants and animals, is specific for CTP as phosphate donor. It does not use farnesol as substrate (cf. EC 2.7.1.216, farnesol kinase).
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CTP + (2E,6E)-farnesyl phosphate
CDP + (2E,6E)-farnesyl diphosphate
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CTP + (2E,6E)-farnesyl phosphate
CDP + (2E,6E)-farnesyl diphosphate
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CTP + (2E,6E)-farnesyl phosphate
CDP + (2E,6E)-farnesyl diphosphate
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Substrates: the enzyme is specific for CTP as phosphate donor Products: -
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Substrates: the enzyme is specific for CTP as phosphate donor. It does not use farnesol as substrate Products: -
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CHAPS
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activation at 0.05%
deoxycholate
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activation at 0.05%
octyl beta-D-glucopyranoside
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activation at 0.05%
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localized on the cytoplasmic side of the membrane
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Highest Expressing Human Cell Lines
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Gene Links
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expression Saccharomyces cerevisiae
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in wild-type plants, exogenous abscisic acid represses FOLK gene expression
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Bentinger, M.; Gruenler, J.; Peterson, E.; Swiezewska, E.; Dallner, G.
Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase
Arch. Biochem. Biophys.
353
191-198
1998
Rattus norvegicus
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Fitzpatrick, A.H.; Bhandari, J.; Crowell, D.N.
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis
Plant J.
66
1078-1088
2011
Arabidopsis thaliana
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