BRENDA Home
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
The taxonomic range for the selected organisms is: Danio rerio
The enzyme appears in selected viruses and cellular organisms
Synonyms
phosphotransferase, adenylate kinase, myokinase, adenylate kinase 1, adenylate kinase 2, nonstructural protein 4b, cinap, adenylokinase, spadk, adenylate kinase isoenzyme 1,
morePlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
adenylate kinase 2
isoform
kinase, adenylate (phosphorylating)
-
-
-
-
kinase, myo- (phosphorylating)
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
phospho group transfer
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP:AMP phosphotransferase
Inorganic triphosphate can also act as donor.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ATP + AMP
ADP + ADP
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
Uniprot
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KAD2_DANRE
241
0
26616
Swiss-Prot
other Location (Reliability: 1)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
I28V/I118V/I173V
lower temperature stability than wild-type enzyme
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
36.2
T-value, mutant enzyme I28V/I118V/I173V
45.1
T-value, wild-type enzyme
56.5
T-value, mutant enzyme I28V/I118V/I173V, in presence of P1,P5-di(adenosine 5')-pentaphosphate
61.8
T-value, wild-type enzyme, in presence of P1,P5-di(adenosine 5')-pentaphosphate
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
P1,P5-di(adenosine 5')-pentaphosphate binding stabilizes the enzyme
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expression in Escherichia coli
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Pannicke, U.; Hoenig, M.; Hess, I.; Friesen, C.; Holzmann, K.; Rump, E.M.; Barth, T.F.; Rojewski, M.T.; Schulz, A.; Boehm, T.; Friedrich, W.; Schwarz, K.
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2
Nat. Genet.
41
101-105
2009
Homo sapiens, Danio rerio (Q1L8L9), Danio rerio
brenda
Moon, S.; Kim, J.; Bae, E.
Structural analyses of adenylate kinases from Antarctic and tropical fishes for understanding cold adaptation of enzymes
Sci. Rep.
7
16027
2017
Xiphophorus maculatus, Poecilia reticulata, Notothenia coriiceps (A0A2R2JFU5), Notothenia coriiceps, Danio rerio (Q68EH2), Danio rerio
brenda
2.7.4.3 adenylate kinase
top
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
