Reference on EC 2.7.4.2 - phosphomevalonate kinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bloch, K.; Chaykin, S.; Phillips, A.H.; De Waard, A.
Mevalonic acid pyrophosphate and isopentenylpyrophosphate
J. Biol. Chem.
234
2595-2604
1959
Saccharomyces cerevisiae
Eyzaguirre, J.; Bazaes, S.
Phosphomevalonate kinase from pig liver
Methods Enzymol.
110
78-85
1985
Sus scrofa
Popjak, G.; Parker, T.S.; Sarin, V.; Tropp, B.E.; Engel, R.
Inhibition of 5-phosphomevalonate kinase by an isosteric analogue of 5-phosphomevalonate
J. Am. Chem. Soc.
100
8014-8016
1978
Rattus norvegicus
-
Skilleter, D.N.; Kekwick, R.G.O.
The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis
Biochem. J.
124
407-417
1971
Hevea brasiliensis
Bazaes, S.; Beytia, E.; Jabalquinto, A.M.; Solis de Ovando, F.; Gomez, I.; Eyzaguirre, J.
Pig liver phosphomevalone kinase. 1. Purification and properties
Biochemistry
19
2300-2304
1980
Sus scrofa
Bazaes, S.; Beytia, E.; Jabalquinto, A.M.; Solis de Ovando, F.; Gomez, I.
Pig liver phosphomevalonate kinase. 2. Participation of cysteinyl and lysyl groups in catalysis
Biochemistry
19
2305-2310
1980
Sus scrofa
Shama Bhat, C.; Ramasarma, T.
Inhibition of rat liver mevalonate pyrophosphate decarboxylase and mevalonate phosphate kinase by phenyl and phenolic compounds
Biochem. J.
181
143-151
1979
Rattus norvegicus
Schulte, A.E.; Van der Heijden, R.; Verpoorte, R.
Purification and characterization of phosphomevalonate kinase from Catharanthus roseus
Phytochemistry
52
975-983
1999
Catharanthus roseus
-
Olivier, L.M.; Chambliss, K.L.; Gibson, K.M.; Krisans, S.K.
Characterization of phosphomevalonate kinase: chromosomal localization, regulation, and subcellular targeting
J. Lipid Res.
40
672-679
1999
Rattus norvegicus, Homo sapiens (Q15126), Homo sapiens
Romanowski, M.J.; Bonanno, J.B.; Burley, S.K.
Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily
Proteins Struct. Funct. Genet.
47
568-571
2002
Streptococcus pneumoniae, Staphylococcus aureus
Pilloff, D.; Dabovic, K.; Romanowski, M.J.; Bonanno, J.B.; Doherty, M.; Burley, S.K.; Leyh, T.S.
The kinetic mechanism of phosphomevalonate kinase
J. Biol. Chem.
278
4510-4515
2003
Streptococcus pneumoniae
Hogenboom, S.; Tuyp, J.J.; Espeel, M.; Koster, J.; Wanders, R.J.; Waterham, H.R.
Phosphomevalonate kinase is a cytosolic protein in humans
J. Lipid Res.
45
697-705
2004
Homo sapiens
Doun, S.S.; Burgner, J.W.2nd.; Briggs, S.D.; Rodwell, V.W.
Enterococcus faecalis phosphomevalonate kinase
Protein Sci.
14
1134-1139
2005
Enterococcus faecalis, Enterococcus faecalis 41
Eyzaguirre, J.; Valdebenito, D.; Cardemil, E.
Pig liver phosphomevalonate kinase: kinetic mechanism
Arch. Biochem. Biophys.
454
188-195
2006
Sus scrofa
Herdendorf, T.J.; Miziorko, H.M.
Phosphomevalonate kinase: functional investigation of the recombinant human enzyme
Biochemistry
45
3235-3242
2006
Homo sapiens (Q15126), Homo sapiens
Herdendorf, T.J.; Miziorko, H.M.
Functional evaluation of conserved basic residues in human phosphomevalonate kinase
Biochemistry
46
11780-11788
2007
Homo sapiens, Homo sapiens (Q15126)
Schirra, F.; Richards, S.M.; Sullivan, D.A.
Androgen influence on cholesterogenic enzyme mRNA levels in the mouse meibomian gland
Curr. Eye Res.
32
393-398
2007
Mus musculus
Flock, G.; Baggio, L.L.; Longuet, C.; Drucker, D.J.
Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice
Diabetes
56
3006-3013
2007
Mus musculus
Olson, A.L.; Yao, H.; Herdendorf, T.J.; Miziorko, H.M.; Hannongbua, S.; Saparpakorn, P.; Cai, S.; Sem, D.S.
Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism
Proteins
75
127-138
2008
Homo sapiens
Chang, Q.; Yan, X.; Gu, S.; Liu, J.; Liang, D.
Crystal structure of human phosphomevalonate kinase at 1.8 A resolution
Proteins Struct. Funct. Bioinform.
73
254-258
2008
Homo sapiens (Q15126)
Battilana, J.; Costantini, L.; Emanuelli, F.; Sevini, F.; Segala, C.; Moser, S.; Velasco, R.; Versini, G.; Stella Grando, M.
The 1-deoxy-D: -xylulose 5-phosphate synthase gene co-localizes with a major QTL affecting monoterpene content in grapevine
Theor. Appl. Genet.
118
653-669
2009
Vitis vinifera x Vitis vinifera, Vitis vinifera x Vitis riparia
Andreassi, J.L.; Vetting, M.W.; Bilder, P.W.; Roderick, S.L.; Leyh, T.S.
Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family
Biochemistry
48
6461-6468
2009
Streptococcus pneumoniae
Kudoh, T.; Park, C.S.; Lefurgy, S.T.; Sun, M.; Michels, T.; Leyh, T.S.; Silverman, R.B.
Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae
Bioorg. Med. Chem.
18
1124-1134
2009
Streptococcus pneumoniae
Chang, Q.; Yan, X.; Gu, S.; Liu, J.; Liang, D.
Crystal structure of human phosphomevalonate kinase at 1.8 A resolution
Proteins
73
254-258
2008
Homo sapiens
Boonsri, P.; Neumann, T.S.; Olson, A.L.; Cai, S.; Herdendorf, T.J.; Miziorko, H.M.; Hannongbua, S.; Sem, D.S.
Molecular docking and NMR binding studies to identify novel inhibitors of human phosphomevalonate kinase
Biochem. Biophys. Res. Commun.
430
313-319
2013
Homo sapiens (Q15126), Homo sapiens
Nishimura, H.; Azami, Y.; Miyagawa, M.; Hashimoto, C.; Yoshimura, T.; Hemmi, H.
Biochemical evidence supporting the presence of the classical mevalonate pathway in the thermoacidophilic archaeon Sulfolobus solfataricus
J. Biochem.
153
415-420
2013
Saccharolobus solfataricus (Q97UL6), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97UL6)
Guirimand, G.; Simkin, A.J.; Papon, N.; Besseau, S.; Burlat, V.; St-Pierre, B.; Giglioli-Guivarch, N.; Clastre, M.; Courdavault, V.
Cycloheximide as a tool to investigate protein import in peroxisomes: a case study of the subcellular localization of isoprenoid biosynthetic enzymes
J. Plant Physiol.
169
825-829
2012
Catharanthus roseus (F6K7K0), Catharanthus roseus, Catharanthus roseus C20A (F6K7K0)
Nowroozi, F.F.; Baidoo, E.E.; Ermakov, S.; Redding-Johanson, A.M.; Batth, T.S.; Petzold, C.J.; Keasling, J.D.
Metabolic pathway optimization using ribosome binding site variants and combinatorial gene assembly
Appl. Microbiol. Biotechnol.
98
1567-1581
2014
Homo sapiens
Garcia, D.E.; Keasling, J.D.
Kinetics of phosphomevalonate kinase from Saccharomyces cerevisiae
PLoS ONE
9
e87112
2014
Saccharomyces cerevisiae (P24521), Saccharomyces cerevisiae
Motoyama, K.; Sobue, F.; Kawaide, H.; Yoshimura, T.; Hemmi, H.
Conversion of mevalonate 3-kinase into 5-phosphomevalonate 3-kinase by single amino acid mutations
Appl. Environ. Microbiol.
85
e00256-19
2019
Saccharomyces cerevisiae (P24521), Saccharomyces cerevisiae ATCC 204508 (P24521)
Song, Q.; Meng, X.; Liao, Y.; Zhang, W.; Ye, J.; Xu, F.
Transcriptome-guided gene isolation, characterization and expression analysis of a phosphomevalonate kinase gene (GbPMK) from Ginkgo biloba
Int. J. Agric. Biol.
20
1080-1088
2018
Ginkgo biloba (A0A346QPQ2)
-
Huang, M.; Wei, K.; Li, X.; McClory, J.; Hu, G.; Zou, J.W.; Timson, D.
Phosphorylation mechanism of phosphomevalonate kinase implications for rational engineering of isoprenoid biosynthetic pathway enzymes
J. Phys. Chem. B
120
10714-10722
2016
Streptococcus pneumoniae
Wang, J.; Liu, Y.; Liu, F.; Huang, C.; Han, S.; Lv, Y.; Liu, C.J.; Zhang, S.; Qin, Y.; Ling, L.; Gao, M.; Yu, S.; Li, C.; Huang, M.; Liao, S.; Hu, X.; Lu, Z.; Liu, X.; Jiang, T.; Tang, Z.; Zhang, H.; Guo, A.Y.; Liu, M.
Loss-of-function mutation in PMVK causes autosomal dominant disseminated superficial porokeratosis
Sci. Rep.
6
24226
2016
Homo sapiens (Q15126)
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