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Information on EC 2.7.2.1 - acetate kinase and Organism(s) Salmonella typhimurium and UniProt Accession P63411

for references in articles please use BRENDA:EC2.7.2.1
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EC Tree
IUBMB Comments
Requires Mg2+ for activity. While purified enzyme from Escherichia coli is specific for acetate , others have found that the enzyme can also use propanoate as a substrate, but more slowly . Acetate can be converted into the key metabolic intermediate acetyl-CoA by coupling acetate kinase with EC 2.3.1.8, phosphate acetyltransferase. Both this enzyme and EC 2.7.2.15, propionate kinase, play important roles in the production of propanoate .
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This record set is specific for:
Salmonella typhimurium
UNIPROT: P63411
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
acetate kinase, ack, acetokinase, acka2, acka1, ackase, urkinase, atp-ecoak, acetic kinase, atp-specific ak, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
acetate kinase (phosphorylating)
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acetic kinase
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acetokinase
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AK
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:acetate phosphotransferase
Requires Mg2+ for activity. While purified enzyme from Escherichia coli is specific for acetate [4], others have found that the enzyme can also use propanoate as a substrate, but more slowly [7]. Acetate can be converted into the key metabolic intermediate acetyl-CoA by coupling acetate kinase with EC 2.3.1.8, phosphate acetyltransferase. Both this enzyme and EC 2.7.2.15, propionate kinase, play important roles in the production of propanoate [9].
CAS REGISTRY NUMBER
COMMENTARY hide
9027-42-3
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