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Information on EC - acetate kinase

for references in articles please use BRENDA:EC2.7.2.1
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IUBMB Comments
Requires Mg2+ for activity. While purified enzyme from Escherichia coli is specific for acetate , others have found that the enzyme can also use propanoate as a substrate, but more slowly . Acetate can be converted into the key metabolic intermediate acetyl-CoA by coupling acetate kinase with EC, phosphate acetyltransferase. Both this enzyme and EC, propionate kinase, play important roles in the production of propanoate .
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Word Map
The enzyme appears in viruses and cellular organisms
acetate kinase, ack, acetokinase, acka2, acka1, ackase, atp-ecoak, urkinase, acetic kinase, atp-specific ak, more
ATP + acetate = ADP + acetyl phosphate
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ATP + propanoate = ADP + propanoyl phosphate
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