Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.7.13.3 - histidine kinase and Organism(s) Staphylococcus aureus

for references in articles please use BRENDA:EC2.7.13.3
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.13 Protein-histidine kinases
                2.7.13.3 histidine kinase
IUBMB Comments
This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). A number of histones can act as acceptor.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Staphylococcus aureus
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Staphylococcus aureus
The enzyme appears in selected viruses and cellular organisms
Synonyms
histidine kinase, sensor kinase, sensor protein, phytochrome a, ethylene receptor, sensor histidine kinase, bacteriophytochrome, ornithine decarboxylase antizyme, chemotaxis protein, hybrid histidine kinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
receptor histidine kinase
-
-
sensor histidine kinase
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:protein-L-histidine N-phosphotransferase
This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). A number of histones can act as acceptor.
CAS REGISTRY NUMBER
COMMENTARY hide
99283-67-7
protein-histidine kinases, EC 2.7.13.1, EC 2.7.13.2, and EC 2.7.13.3 are not distinguished in Chemical Abstracts
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + protein L-histidine
ADP + protein N-phospho-L-histidine
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
in vitro autokinase activity of recombinant truncated enzyme mutant AgrCTM5-6C in N,N-dimethyldodecylamine N-oxide proteoliposomes
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + protein L-histidine
ADP + protein N-phospho-L-histidine
show the reaction diagram
-
-
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
-
required
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)methanaminium chloride
-
-
2-(4-[2-[4-(4-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
-
2-(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
-
Zn2+
Zn2+ binding negatively regulates the WalKR regulon. Zn2+ binding directly influences the relative positioning of the PAS and catalytic domains of WalK
additional information
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
auto-inducible protein I
-
dose-dependent activation by autoinducing peptide
-
DTT
-
required
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
additional information
-
kinase activity of recombinant enzyme AgrCTM5-6C in N,N-dimethyldodecylamine N-oxide micelles or proteoliposomes
-
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.4
-
assay at
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
an integral membrane protein, protein transmembrane topology in proteoliposomes is determined using membrane-impermeable and membrane-permeable thiol-reactive reagents, overview
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
WALK_STAAU
415
0
47818
Swiss-Prot
-
SRRB_STAAU
583
2
66106
Swiss-Prot
-
A0A6B5EEA7_STAAU
885
4
102186
TrEMBL
-
A0A389PZB6_STAAU
370
0
41880
TrEMBL
-
A0A133Q146_STAAU
313
2
36168
TrEMBL
-
A0A6B5Q3T4_STAAU
346
2
41093
TrEMBL
-
A0A1L6C127_STAAU
346
2
41127
TrEMBL
-
A0A0U1MRD2_STAAU
885
4
102213
TrEMBL
-
A0A6B0CSW2_STAAU
351
2
39748
TrEMBL
-
A0A1Q8DHL6_STAAU
457
2
52863
TrEMBL
-
A0A6H3Q9I2_STAAU
885
4
102207
TrEMBL
-
A0A8F7WZ12_STAAU
885
4
102279
TrEMBL
-
A0A7H9CDV0_STAAU
309
0
35070
TrEMBL
-
A0A6G4IV78_STAAU
553
2
63762
TrEMBL
-
A0A133QC13_STAAU
451
2
52409
TrEMBL
-
A0A133PUE0_STAAU
909
4
105089
TrEMBL
-
A0A6B5IF64_STAAU
230
0
25978
TrEMBL
-
A0A6C0PQL0_STAAU
608
2
69943
TrEMBL
-
A0A2X2LZB2_STAAU
70
0
8137
TrEMBL
-
A0A380EEJ7_STAAU
52
0
5643
TrEMBL
-
A0A6B5DE64_STAAU
579
6
64499
TrEMBL
-
A0A6B5S4S6_STAAU
346
2
41045
TrEMBL
-
A0A6B5H090_STAAU
346
2
41094
TrEMBL
-
A0A1L6C0E0_STAAU
608
2
69944
TrEMBL
-
A0A5S9C4S1_STAAU
430
6
49908
TrEMBL
-
A0A2X2MEF7_STAAU
137
0
15639
TrEMBL
-
A0A2X2JR16_STAAU
163
0
18332
TrEMBL
-
A0A380DXQ1_STAAU
117
0
13477
TrEMBL
-
A0A380DVI0_STAAU
747
4
86348
TrEMBL
-
A0A0D1HXT6_STAAU
186
0
20019
TrEMBL
-
A0A6N3AU45_STAAU
584
6
65029
TrEMBL
-
A0A0F7H1Q7_STAAU
351
2
39728
TrEMBL
-
A0A0D6G3C7_STAAU
346
2
41079
TrEMBL
-
A0A0D3Q3U7_STAAU
518
2
61047
TrEMBL
-
A0A1L6C0A3_STAAU
347
2
40002
TrEMBL
-
A0A0U1MKE0_STAAU
363
6
41841
TrEMBL
-
A0A380E0V5_STAAU
346
2
41058
TrEMBL
-
A0A1L6C0J1_STAAU
608
2
69923
TrEMBL
-
A0A7H9C584_STAAU
376
0
42638
TrEMBL
-
A0A6G4N4W2_STAAU
457
2
52351
TrEMBL
-
A0A2X2M8I9_STAAU
81
0
9190
TrEMBL
-
A0A6B5L4J9_STAAU
885
4
102188
TrEMBL
-
A0A6B5HVU7_STAAU
346
2
40963
TrEMBL
-
A0A1Q8DD73_STAAU
565
2
64858
TrEMBL
-
A0A830YN19_STAAU
546
2
62823
TrEMBL
-
A0A6B5HKE4_STAAU
298
1
34736
TrEMBL
-
A0A1L6C093_STAAU
347
2
40045
TrEMBL
-
A0A380EMR4_STAAU
368
0
42261
TrEMBL
-
A0A6B5Q0Q3_STAAU
370
0
41854
TrEMBL
-
A0A6B5DM06_STAAU
370
0
41900
TrEMBL
-
A0A6B0BMQ8_STAAU
424
2
49384
TrEMBL
-
A0A1Q8DD40_STAAU
369
0
41779
TrEMBL
-
A0A380E1P7_STAAU
83
0
9198
TrEMBL
-
A0A2X2K769_STAAU
334
1
38748
TrEMBL
-
A0A7U3XLA5_STAAU
885
4
102110
TrEMBL
-
A0A7Z8GBX9_STAAU
608
2
69940
TrEMBL
-
A0A6B0ACG1_STAAU
457
2
52399
TrEMBL
-
A0A1L6C0H2_STAAU
608
2
69940
TrEMBL
-
A0A0U1MPI5_STAAU
554
2
63877
TrEMBL
-
A0A6B0CUG0_STAAU
346
2
41011
TrEMBL
-
A0A7Z8D8Y0_STAAU
885
4
102169
TrEMBL
-
A0A6G4JLY7_STAAU
280
2
32071
TrEMBL
-
A0A1L6C0B2_STAAU
347
2
39984
TrEMBL
-
A0A2X2K105_STAAU
145
0
16540
TrEMBL
-
A0A0D1JV41_STAAU
584
6
65056
TrEMBL
-
A0A2X2M3R0_STAAU
84
0
9645
TrEMBL
-
A0A391F3W4_STAAU
363
5
41661
TrEMBL
-
A0A641A3G4_STAAU
885
4
102124
TrEMBL
-
A0A1L6C0Z8_STAAU
346
2
41079
TrEMBL
-
A0A125SXT4_STAAU
877
4
100611
TrEMBL
-
A0A6B5S3I8_STAAU
344
0
39134
TrEMBL
-
A0A8G0JFC7_STAAU
347
2
40034
TrEMBL
-
A0A1L6C0E5_STAAU
608
2
69967
TrEMBL
-
A0A641A519_STAAU
370
0
41891
TrEMBL
-
A0A6B5KVN9_STAAU
280
2
31889
TrEMBL
-
A0A6B5KY86_STAAU
370
0
41858
TrEMBL
-
A0A454GZN1_STAAU
351
2
39726
TrEMBL
-
A0A6B0CTT5_STAAU
457
2
52402
TrEMBL
-
A0A1L6C0D0_STAAU
608
2
69951
TrEMBL
-
A0A0D1JZW0_STAAU
582
2
65900
TrEMBL
-
A0A1L6C0F3_STAAU
608
2
69938
TrEMBL
-
A0A6F9YS47_STAAU
546
2
62856
TrEMBL
-
A0A1L6C092_STAAU
347
2
40103
TrEMBL
-
A0A2X2JS19_STAAU
287
2
33416
TrEMBL
-
A0A1Q8DFH8_STAAU
608
2
69914
TrEMBL
-
A0A2X2K595_STAAU
141
0
16081
TrEMBL
-
A0A380EJP4_STAAU
138
0
15584
TrEMBL
-
A0A0C5HV46_STAAU
363
5
41631
TrEMBL
-
A0A0D6HAQ4_STAAU
885
4
102219
TrEMBL
-
A0A2S6DD24_STAAU
457
2
52372
TrEMBL
-
A0A0D1IMN4_STAAU
347
2
40045
TrEMBL
-
A0A0D6HHL7_STAAU
554
2
63905
TrEMBL
-
A0A6G4J8Z2_STAAU
414
2
47689
TrEMBL
-
A0A6B5TZ08_STAAU
370
0
41900
TrEMBL
-
A0A380EI17_STAAU
234
0
26484
TrEMBL
-
A0A2X2MD73_STAAU
664
3
76809
TrEMBL
-
A0A6B5FNC3_STAAU
275
6
32143
TrEMBL
-
A0A2X2K1M3_STAAU
231
0
26201
TrEMBL
-
A0A853PDU3_STAAU
554
2
63897
TrEMBL
-
A0A380EEI1_STAAU
395
0
44050
TrEMBL
-
A0A5C8X9G3_STAAU
230
0
26004
TrEMBL
-
A0A2X2K4H4_STAAU
101
2
11806
TrEMBL
-
A0A380EJF4_STAAU
125
1
14390
TrEMBL
-
X5ELZ2_STAAU
370
0
41881
TrEMBL
-
W8U6X2_STAAU
584
6
65029
TrEMBL
-
A0A2U0IQC9_STAAU
583
2
66062
TrEMBL
-
A0A6B1RJD9_STAAU
346
2
41017
TrEMBL
-
A0A6N8I794_STAAU
451
2
52404
TrEMBL
-
A0A6H3Q476_STAAU
518
2
61077
TrEMBL
-
A0A6G4N4G2_STAAU
551
2
63517
TrEMBL
-
A0A380DTJ8_STAAU
457
2
52427
TrEMBL
-
A0A8G2HWC7_STAAU
554
2
63895
TrEMBL
-
A0A830YN17_STAAU
583
1
66993
TrEMBL
-
A0A850G6P2_STAAU
553
2
63758
TrEMBL
-
A0A2S6DQQ4_STAAU
553
2
63823
TrEMBL
-
A0A7I8NM31_STAAU
351
2
39741
TrEMBL
-
A0A7Z8DFA2_STAAU
363
5
41671
TrEMBL
-
A0A6B5HQ05_STAAU
457
2
52442
TrEMBL
-
A0A6B5HHC6_STAAU
252
0
28631
TrEMBL
-
A0A380EKM0_STAAU
65
0
7450
TrEMBL
-
A0A2X2LZ10_STAAU
67
1
7850
TrEMBL
-
A0A1L6C0A1_STAAU
347
2
40079
TrEMBL
-
A0A2X2JWI5_STAAU
74
0
8733
TrEMBL
-
A0A380EJH9_STAAU
69
0
7873
TrEMBL
-
A0A380EKS1_STAAU
56
0
6685
TrEMBL
-
A0A380DT60_STAAU
367
0
42239
TrEMBL
-
A0A6B5H0J9_STAAU
370
0
41952
TrEMBL
-
A0A811FR92_STAAU
309
2
35656
TrEMBL
-
A0A0U1MSB2_STAAU
457
2
52372
TrEMBL
-
A0A6B1RKR7_STAAU
457
2
52386
TrEMBL
-
A0A6A9GX29_STAAU
583
2
66044
TrEMBL
-
A0A2S6DMU4_STAAU
885
4
102107
TrEMBL
-
A0A6B0D500_STAAU
885
4
102199
TrEMBL
-
A0A850FY98_STAAU
347
2
40075
TrEMBL
-
A0A898CQJ0_STAAU
584
6
65030
TrEMBL
-
A0A7U3XM19_STAAU
457
2
52389
TrEMBL
-
A0A2I6SBA4_STAAU
378
2
43220
TrEMBL
-
A0A8G0J5P0_STAAU
583
2
66004
TrEMBL
-
A0A831EEC0_STAAU
233
2
27024
TrEMBL
-
A0A7H9CBY0_STAAU
554
2
63933
TrEMBL
-
A0A6B5IJA3_STAAU
292
0
34542
TrEMBL
-
A0A380EN18_STAAU
200
0
23251
TrEMBL
-
A0A380E3C4_STAAU
370
0
41909
TrEMBL
-
A0A6B5Q4Z6_STAAU
363
5
41677
TrEMBL
-
D3X7X9_STAAU
100
0
11285
TrEMBL
-
A0A641A6N0_STAAU
457
2
52348
TrEMBL
-
A0A2I7YBL3_STAAU
553
2
63773
TrEMBL
-
A0A6B5D8D1_STAAU
608
2
69952
TrEMBL
-
A0A6B5I754_STAAU
608
2
69884
TrEMBL
-
A0A6G4N6R3_STAAU
264
0
30040
TrEMBL
-
A0A8G2CH52_STAAU
295
2
34088
TrEMBL
-
A0A6B5LZG1_STAAU
457
2
52362
TrEMBL
-
A0A8G2I233_STAAU
457
2
52364
TrEMBL
-
A0A8G2M7S4_STAAU
583
2
66106
TrEMBL
-
A0A1L6C0E9_STAAU
608
2
69919
TrEMBL
-
A0A6B5HPX6_STAAU
885
4
102160
TrEMBL
-
A0A1L6C076_STAAU
347
2
40030
TrEMBL
-
A0A380ENY4_STAAU
197
0
22905
TrEMBL
-
A0A380E2K0_STAAU
156
0
18103
TrEMBL
-
A0A1L6C0V1_STAAU
346
2
41051
TrEMBL
-
A0A6B5CXC5_STAAU
370
0
41755
TrEMBL
-
M1XHR3_STAAU
906
4
104060
TrEMBL
-
A0A0U1MGT7_STAAU
346
2
40934
TrEMBL
-
Q309Z2_STAAU
430
6
49776
TrEMBL
-
A0A380E4U1_STAAU
281
2
32738
TrEMBL
-
A0A6B3IGH6_STAAU
583
2
66066
TrEMBL
-
A0A830YUL2_STAAU
317
3
36362
TrEMBL
-
A0A1Q8DC11_STAAU
332
2
38712
TrEMBL
-
A0A7U3XKQ3_STAAU
370
0
41853
TrEMBL
-
A0A6B0B9T6_STAAU
242
0
28193
TrEMBL
-
A0A6H3QA77_STAAU
346
2
41045
TrEMBL
-
A0A380EJM6_STAAU
148
0
16864
TrEMBL
-
A0A380E253_STAAU
97
2
10919
TrEMBL
-
A0A6B5Q907_STAAU
885
4
102157
TrEMBL
-
A0A7K3N153_STAAU
885
4
102150
TrEMBL
-
A0A808JSM8_STAAU
608
2
69938
TrEMBL
-
A0A8G2MBC8_STAAU
885
4
102152
TrEMBL
-
A0A8G2M8V5_STAAU
608
2
69912
TrEMBL
-
A0A8G1LPU6_STAAU
344
0
39118
TrEMBL
-
A0A7I8NJC0_STAAU
554
2
63955
TrEMBL
-
A0A6B5I1Z9_STAAU
583
2
66018
TrEMBL
-
A0A380DHJ9_STAAU
317
0
36964
TrEMBL
-
A0A5S9EVI0_STAAU
546
2
62850
TrEMBL
-
A0A380DWH0_STAAU
457
2
52287
TrEMBL
-
A0A380E1Y4_STAAU
233
0
26519
TrEMBL
-
A0A7H9C3Y8_STAAU
426
1
49493
TrEMBL
-
A0A6B5K318_STAAU
885
4
102200
TrEMBL
-
A0A811I6K1_STAAU
881
4
101805
TrEMBL
-
A0A380EL19_STAAU
54
0
5901
TrEMBL
-
A0A380DUZ6_STAAU
256
0
28836
TrEMBL
-
A0A6B5CK38_STAAU
885
4
102140
TrEMBL
-
A0A1L6C0D8_STAAU
608
2
69905
TrEMBL
-
A0A5F0HN67_STAAU
457
2
52373
TrEMBL
-
W8U3I5_STAAU
344
0
39120
TrEMBL
-
A0A6G4ISA8_STAAU
295
2
34034
TrEMBL
-
A0A658WF83_STAAU
608
2
69926
T