Reference on EC 2.7.12.2 - mitogen-activated protein kinase kinase and Organism(s) Rattus norvegicus and UniProt Accession Q01986
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Otsu, M.; Terada, Y.; Okayama, H.
Isolation of two members of the rat MAP kinase kinase gene family
FEBS Lett.
320
246-250
1993
Rattus norvegicus (P36506), Rattus norvegicus (Q01986)
Wu, J.; Harrison, J.K.; Dent, P.; Lynch, K.R.; Weber, M.J.; Sturgill, T.W.
Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2
Mol. Cell. Biol.
13
4539-4548
1993
Rattus norvegicus (P36506)
Doring, F.; Drewes, G.; Berling, B.; Mandelkow, E.M.
Cloning and sequencing of a cDNA encoding rat brain mitogen-activated protein (MAP) kinase activator
Gene
131
303-304
1993
Rattus norvegicus (Q01986)
Wu, J.; Harrison, J.K.; Vincent, L.A.; Haystead, C.; Haystead, T.A.; Michel, H.; Hunt, D.F.; Lynch, K.R.; Sturgill, T.W.
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase
Proc. Natl. Acad. Sci. USA
90
173-177
1993
Rattus norvegicus (Q01986)
English, J.M.; Vanderbilt, C.A.; Xu, S.; Marcus, S.; Cobb, M.H.
Isolation of MEK5 and differential expression of alternatively spliced forms
J. Biol. Chem.
270
28897-28902
1995
Rattus norvegicus (Q62862)
Xu, S.; Robbins, D.J.; Christerson, L.B.; English, J.M.; Vanderbilt, C.A.; Cobb, M.H.
Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain
Proc. Natl. Acad. Sci. USA
93
5291-5295
1996
Rattus norvegicus (Q62925)
Teo, M.; Manser, E.; Lim, L.
Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
J. Biol. Chem.
270
26690-26697
1995
Rattus norvegicus (Q64303)
Gil, C.; Chaib-Oukadour, I.; Aguilera, J.
C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons
Biochem. J.
373
613-620
2003
Rattus norvegicus
Liang, K.W.; Ting, C.T.; Yin, S.C.; Chen, Y.T.; Lin, S.J.; Liao, J.K.; Hsu, S.L.
Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury
Biochem. Pharmacol.
71
806-817
2006
Rattus norvegicus
Atwal, J.K.; Singh, K.K.; Tessier-Lavigne, M.; Miller, F.D.; Kaplan, D.R.
Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse
J. Neurosci.
23
7602-7609
2003
Rattus norvegicus
Lee, S.D.; Chang, S.H.; Kuo, W.H.; Ying, T.H.; Kuo, W.W.; Li, P.C.; Hsu, H.H.; Lu, M.C.; Ting, H.; Huang, C.Y.
Role of mitogen-activated protein kinase kinase in Porphyromonas gingivalis-induced myocardial cell hypertrophy and apoptosis
Eur. J. Oral Sci.
114
154-159
2006
Rattus norvegicus
Whitmarsh, A.J.; Davis, R.J.
Role of mitogen-activated protein kinase kinase 4 in cancer
Oncogene
26
3172-3184
2007
Drosophila melanogaster, Homo sapiens, Homo sapiens (O14733), Homo sapiens (P45985), Mus musculus, Mus musculus (P47809), Mus musculus (Q8CE90), Rattus norvegicus, Xenopus laevis
Chen, Y.C.; Huang, S.H.; Wang, S.M.
Adenosine-stimulated adrenal steroidogenesis involves the adenosine A2A and A2B receptors and the Janus kinase 2-mitogen-activated protein kinase kinase-extracellular signal-regulated kinase signaling pathway
Int. J. Biochem. Cell Biol.
40
2815-2825
2008
Rattus norvegicus
Xia, Y.; Wang, C.Z.; Liu, J.; Anastasio, N.C.; Johnson, K.M.
Lithium protection of phencyclidine-induced neurotoxicity in developing brain: the role of phosphatidylinositol-3 kinase/Akt and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling pathways
J. Pharmacol. Exp. Ther.
326
838-848
2008
Rattus norvegicus
Maharjan, S.; Serova, L.I.; Sabban, E.L.
Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ERalpha in PC12 cells
J. Neurochem.
112
42-55
2010
Rattus norvegicus
Bassi, R.; Burgoyne, J.R.; DeNicola, G.F.; Rudyk, O.; DeSantis, V.; Charles, R.L.; Eaton, P.; Marber, M.S.
Redox-dependent dimerization of p38alpha mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3
J. Biol. Chem.
292
16161-16173
2017
Rattus norvegicus (B1H230)
