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Information on EC 2.7.11.5 - [Isocitrate dehydrogenase (NADP+)] kinase

for references in articles please use BRENDA:EC2.7.11.5
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IUBMB Comments
The enzyme has no activating compound but is specific for its substrate. Phosphorylates and inactivates EC 1.1.1.42, isocitrate dehydrogenase (NADP+).
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The enzyme appears in viruses and cellular organisms
Synonyms
isocitrate dehydrogenase kinase/phosphatase, idh kinase/phosphatase, idh kinase, idhk/p, idh-k/p, icdh kinase/phosphatase, bifunctional isocitrate dehydrogenase kinase/phosphatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [isocitrate dehydrogenase (NADP+)] = ADP + [isocitrate dehydrogenase (NADP+)] phosphate
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