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Information on EC 2.7.11.4 - [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase

for references in articles please use BRENDA:EC2.7.11.4
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IUBMB Comments
The enzyme has no activating compound but is specific for its substrate. It is a mitochondrial enzyme associated with the branched-chain 2-oxoacid dehydrogenase complex. Phosphorylation inactivates EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
bckdh kinase, branched-chain alpha-ketoacid dehydrogenase kinase, bckdk, bckd kinase, branched-chain alpha-keto acid dehydrogenase kinase, bckd-kinase, branched-chain 2-oxo acid dehydrogenase kinase, bckdc kinase, branched-chain oxoacid dehydrogenase complex, branched-chain alpha-keto dehydrogenase kinase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] = ADP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphate
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