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ATP + a protein
ADP + phosphorylated protein
-
-
-
-
?
ATP + Akt
ADP + phosphorylated Akt
-
phosphorylation on Ser473 by isozyme PKCbetaII
-
-
?
ATP + Bcl-xL
ADP + phosphorylated Bcl-xL
-
recombinant human substrate, recombinant isozyme PKCdelta
-
-
?
ATP + calcium-activated potassium channel alpha subunit Slo1
ADP + phosphorylated calcium-activated potassium channel alpha subunit Slo1
-
-
-
-
?
ATP + glycine transporter 2
ADP + phosphorylated glycine transporter 2
-
-
-
-
?
ATP + hematopoietic-specific G-protein Galpha15
ADP + phosphorylated hematopoietic-specific G-protein Galpha15
-
recombinant substrate expressed in COS-7 cells, phosphorylation at Ser334, mutant G-protein Galpha15 S334A is inactive as substrate for PKC
-
-
?
ATP + hematopoietic-specific G-protein Galpha15 peptide
ADP + phosphorylated hematopoietic-specific G-protein Galpha15 peptide
-
the PKC phosphorylation site peptide sequence RKGSR includes Ser334
-
-
?
ATP + hematopoietic-specific G-protein Galpha16
ADP + phosphorylated hematopoietic-specific G-protein Galpha16
-
substrate from HL-60 cells, phosphorylation at Ser336, mutant G-protein Galpha16 S336A is inactive as substrate for PKC
-
-
?
ATP + hematopoietic-specific G-protein Galpha16 peptide
ADP + phosphorylated hematopoietic-specific G-protein Galpha16 peptide
-
the PKC phosphorylation site peptide sequence KKGARSRR includes Ser336
-
-
?
ATP + histone
ADP + phosphorylated histone
ATP + histone H1
ADP + phosphorylated histone H1
-
-
-
-
?
ATP + histone III-SS
ADP + phosphorylated histone III-SS
-
commercial substrate
-
-
?
ATP + histone IIIS
ADP + phosphorylated histone IIIS
poor substrate
-
-
?
ATP + hyperpolarization-activated cyclic nucleotide-gated channel 1 protein
ADP + phosphorylated hyperpolarization-activated cyclic nucleotide-gated channel 1 protein
-
-
-
-
?
ATP + insulin receptor
ADP + phosphorylated insulin receptor
-
isozyme PKCalpha
-
-
?
ATP + insulin receptor substrate 1
ADP + phosphorylated insulin receptor substrate 1
ATP + insulin receptor substrate-1
ADP + phosphorylated insulin receptor substrate-1
ATP + insulin receptor substrate-3
ADP + phosphorylated insulin receptor substrate-3
-
-
-
?
ATP + insulin receptor substrate-4
ADP + phosphorylated insulin receptor substrate-4
-
-
-
?
ATP + IRS
ADP + phosphorylated IRS
-
isozymes PKCalpha and PKCdelta, phosphorylation on Ser307
-
-
?
ATP + LC3
ADP + phosphorylated LC3
-
-
-
-
?
ATP + Na,K-ATPase
ADP + phosphorylated Na,K-ATPase
ATP + pyruvate dehydrogenase kinase
ADP + phosphorylated pyruvate dehydrogenase kinase
-
-
-
?
ATP + RalB
ADP + phosphorylated RalB
-
PKCalpha phosphorylates RalB on Ser-192 and Ser-198 in the hypervariable sequence and Ser-198 phosphorylation promotes activation of RalB and causes RalB relocalization from the plasma membrane to late endosomes
-
-
?
ATP + ribosomal protein S6-(229-239) peptide analogue
ADP + phosphorylated ribosomal protein S6-(229-239) peptide analogue
-
-
-
?
ATP + S6-(229-239) peptide
ADP + phosphorylated S6-(229-239) peptide
-
-
-
?
ATP + serine racemase
ADP + phosphorylated serine racemase
-
-
-
-
?
ATP + serotonin N-acetyltransferase
ADP + phosphorylated serotonin N-acetyltransferase
ATP + sodium channel
ADP + phosphorylated sodium channel
ATP + [low density lipoprotein receptor-related protein]
ADP + phosphorylated [low density lipoprotein receptor-related protein]
additional information
?
-
ATP + histone
ADP + phosphorylated histone
-
-
-
-
?
ATP + histone
ADP + phosphorylated histone
-
in presence of absence of phosphatidylserine-containing liposomes
-
-
?
ATP + insulin receptor substrate 1
ADP + phosphorylated insulin receptor substrate 1
-
phosphorylation of insulin receptor substrate proteins on serine residues is an important posttranslational modification that is linked to insulin resistance, overview
-
-
?
ATP + insulin receptor substrate 1
ADP + phosphorylated insulin receptor substrate 1
-
a bona fide substrate for conventional isozymes PKCalpha, PKCzeta, and PKCdelta, phosphorylation of IRS1 at Ser24 in the N-terminal pleckstrin homology domain of IRS1, additionally isozyme PKCalpha is indirectly involved in Ser307 and Ser612 phosphorylation
-
-
?
ATP + insulin receptor substrate-1
ADP + phosphorylated insulin receptor substrate-1
-
-
-
-
?
ATP + insulin receptor substrate-1
ADP + phosphorylated insulin receptor substrate-1
-
-
-
?
ATP + insulin receptor substrate-1
ADP + phosphorylated insulin receptor substrate-1
Ser357 of rat insulin receptor substrate-1 is a PKC-delta phosphorylation site
-
-
?
ATP + Na,K-ATPase
ADP + phosphorylated Na,K-ATPase
-
-
-
-
?
ATP + Na,K-ATPase
ADP + phosphorylated Na,K-ATPase
-
substrate in membrane vesicles from the rectal gland of the spiny dog fish Squalus acanthias
-
-
?
ATP + serotonin N-acetyltransferase
ADP + phosphorylated serotonin N-acetyltransferase
-
PKC regulates the activity and stability of serotonin N-acetyltransferase in vivo, recombinant enzyme expressed in COS-7 cells
-
-
?
ATP + serotonin N-acetyltransferase
ADP + phosphorylated serotonin N-acetyltransferase
-
recombinant enzyme expressed in COS-7 cells, phosphorylation at Thr29
-
-
?
ATP + sodium channel
ADP + phosphorylated sodium channel
-
-
-
-
?
ATP + sodium channel
ADP + phosphorylated sodium channel
-
PKC mediates inhibition of sodium channels and tetrodotoxin-sensitive transient sodium current by phosphorylation by topiramate, overview
-
-
?
ATP + [low density lipoprotein receptor-related protein]
ADP + phosphorylated [low density lipoprotein receptor-related protein]
-
involved in regulation of endocytosis and association with adaptor molecules, e.g. Shc, Dab1, or CED-6/GULP
-
-
?
ATP + [low density lipoprotein receptor-related protein]
ADP + phosphorylated [low density lipoprotein receptor-related protein]
-
i.e. LPR, phosphorylation of cytoplasmic domain serine and threonine residues
-
-
?
additional information
?
-
PKC deltaIII may show a dominant negative effect against PKC deltaI
-
-
?
additional information
?
-
-
alterations in PKC isoenzyme alpha, delta, and epsilon expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy
-
-
?
additional information
?
-
-
bidirectional regulation of renal cortical Na+,K+-ATPase by PKC
-
-
?
additional information
?
-
-
calcium-dependent protein kinase C activation occurs in acutely isolated neurons during oxygen and glucose deprivation
-
-
?
additional information
?
-
-
intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase and mammalian target of rapamycin-dependent pathways, PKC betaII regulation and degradation control, overview
-
-
?
additional information
?
-
-
isozyme-specific and developmental stage-specific alterations in brain PKC following exposure to a polychlorinated biphenyl mixture
-
-
?
additional information
?
-
-
PKC is involved in regulation of acetylcholine release in cholinergic nervous activity in the central nervous system in hypertension
-
-
?
additional information
?
-
-
PKC regulates Na,K-ATPase isozyme alpha1 specifically via isozyme-specific regions, while it has no effect on isozyme alpha3, overview
-
-
?
additional information
?
-
-
PKCgamma positively regulates P2X7 receptor-mediated calcium signalling in type-2 astrocytes, mechanism, overview
-
-
?
additional information
?
-
-
regulation of amphetamine-stimulated dopamine efflux by PKCbetaII, overview
-
-
?
additional information
?
-
-
some PKC isozymes inhibit BKCa channel activity in pulmonary arterial smooth muscle via inhibition of cAMP-induced activation of the BKCa channel
-
-
?
additional information
?
-
-
isozymes alpha, delta, and epsilon perform autophosphorylation
-
-
?
additional information
?
-
-
phosphorylation by PKC is involved in regulation of hematopoietic-specific G-protein Galpha15 and Galpha16, deletion of the PKC phosphorylation site leads to inhibition of receptor-coupled phospholipase C activation
-
-
?
additional information
?
-
-
involvement of isozyme PKCalpha in the early action of angiotensin II type 2 effects on neurite outgrowth in NG108-15 cells, the angiotensin II type 2-receptor inhibits PKC alpha and p21ras activity, inhibition of PKCalpha is not directly involved in the Rap1-MEK-p42/p44mapk cascade, overview
-
-
?
additional information
?
-
-
regulation of PKC isozyme expression, overview, specific PKC isozymes act as transducers and modulators of insulin signaling, the activation of PKC isozymes by insulin is modified by several effectors, signaling cascade, overview, isozyme PKCalpha might play a role in insulin resistance, overview, isozyme PKCepsilon forms signaling complexes with Raf-1 and ERK, isozyme PKCtheta inactivation prevents fat-induced defects in insulin signaling and glucose transport in skeletal muscle
-
-
?
additional information
?
-
-
PKCbetaII specifically binds to beta-actin
-
-
?
additional information
?
-
-
pertussis toxin-B suppresses HIV-1 Tat-mediated apoptosis by reducing its activation of phospholipase C-beta through a PKC activation pathway
-
-
?
additional information
?
-
-
PKC plays a pivotal role in desensitization of P2Y1 receptors in RBA-2 astrocytes
-
-
?
additional information
?
-
does not phosphorylate insulin receptor substrate-2
-
-
?
additional information
?
-
-
PKCepsilon associates with and inhibits activation of the mitochondrial permeability transition pore complex
-
-
?
additional information
?
-
-
thrombin-induced cyclin D1expression requires the activation of conventional PKC isoforms
-
-
?
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Nishizuka, Y.
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
Nature
334
661-665
1988
Bos taurus (P04409), Bos taurus (P05126), Rattus norvegicus (P05696), Oryctolagus cuniculus (P10102)
brenda
Ono, Y.; Fujii, T.; Igarashi, K.; Kikkawa, U.; Ogita, K.; Nishizuka, Y.
Nucleotide sequences of cDNAs for alpha and gamma subspecies of rat brain protein kinase C
Nucleic Acids Res.
16
5199-5200
1988
Rattus norvegicus (P05696), Mus musculus (P63318)
brenda
Kikkawa, U.; Ogita, K.; Ono, Y.; Asaoka, Y.; Shearman, M.S.; Fujii, T.; Ase, K.; Sekiguchi, K.; Igarashi, K.; Nishizuka, Y.
The common structure and activities of four subspecies of rat brain protein kinase C family
FEBS Lett.
223
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1987
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brenda
Ueyama, T.; Ren, Y.; Ohmori, S.; Sakai, K.; Tamaki, N.; Saito, N.
cDNA cloning of an alternative splicing variant of protein kinase C delta (PKC deltaIII), a new truncated form of PKCdelta, in rats
Biochem. Biophys. Res. Commun.
269
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2000
Rattus norvegicus (P09215)
brenda
Kurkinen, K.M.; Keinanen, R.A.; Karhu, R.; Koistinaho, J.
Genomic structure and chromosomal localization of the rat protein kinase Cdelta-gene
Gene
242
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2000
Rattus norvegicus (P09215)
brenda
Pappa, H.; Murray-Rust, J.; Dekker, L.V.; Parker, P.J.; McDonald, N.Q.
Crystal structure of the C2 domain from protein kinase C-delta
Structure
6
885-894
1998
Rattus norvegicus (P09215)
brenda
Garcia-Paramio, P.; Cabrerizo, Y.; Bornancin, F.; Parker, P.J.
The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation
Biochem. J.
333
631-636
1998
Rattus norvegicus (P09215)
-
brenda
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
The structure, expression, and properties of additional members of the protein kinase C family
J. Biol. Chem.
263
6927-6932
1988
Rattus norvegicus (P09215), Rattus norvegicus (P09216), Rattus norvegicus (P09217)
brenda
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
Identification of three additional members of rat protein kinase C family: delta-, epsilon- and zeta-subspecies
FEBS Lett.
226
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1987
Rattus norvegicus (P09215), Rattus norvegicus (P09216), Rattus norvegicus (P09217)
brenda
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties
Proc. Natl. Acad. Sci. USA
86
3099-3103
1989
Rattus norvegicus (P09217)
brenda
Mukai, H.; Ono, Y.
A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C
Biochem. Biophys. Res. Commun.
199
897-904
1994
Homo sapiens (Q16512), Homo sapiens, Rattus norvegicus (Q63433)
brenda
Morrice, N.A.; Gabrielli, B.; Kemp, B.E.; Wettenhall, R.E.
A cardiolipin-activated protein kinase from rat liver structurally distinct from the protein kinases C
J. Biol. Chem.
269
20040-20046
1994
Rattus norvegicus (Q63433)
brenda
Dekker, L.V.; Parker, P.J.; McIntyre, P.
Biochemical properties of rat protein kinase C-eta expressed in COS cells
FEBS Lett.
312
195-199
1992
Rattus norvegicus (Q64617)
brenda
Choi, B.H.; Chae, H.D.; Park, T.J.; Oh, J.; Lim, J.; Kang, S.S.; Ha, H.; Kim, K.T.
Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase
J. Neurochem.
90
442-454
2004
Rattus norvegicus
brenda
Beltowski, J.; Marciniak, A.; Jamroz-Wisniewska, A.; Borkowska, E.; Wojcicka, G.
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C
Acta Biochim. Pol.
51
757-772
2004
Rattus norvegicus
brenda
Barman, S.A.; Zhu, S.; White, R.E.
Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle
Am. J. Physiol.
286
L149-155
2004
Rattus norvegicus
brenda
Duran, M.J.; Pierre, S.V.; Carr, D.L.; Pressley, T.A.
The isoform-specific region of the Na,K-ATPase catalytic subunit: role in enzyme kinetics and regulation by protein kinase C
Biochemistry
43
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2004
Rattus norvegicus
brenda
Yang, J.H.; Derr-Yellin, E.C.; Kodavanti, P.R.
Alterations in brain protein kinase C isoforms following developmental exposure to a polychlorinated biphenyl mixture
Brain Res. Mol. Brain Res.
111
123-135
2003
Rattus norvegicus
brenda
Hung, A.C.; Chu, Y.J.; Lin, Y.H.; Weng, J.Y.; Chen, H.B.; Au, Y.C.; Sun, S.H.
Roles of protein kinase C in regulation of P2X7 receptor-mediated calcium signalling of cultured type-2 astrocyte cell line, RBA-2
Cell. Signal.
17
1384-1396
2005
Rattus norvegicus
brenda
Geeraert, V.; Dupont, J.L.; Grant, N.J.; Huvet, C.; Chasserot-Golaz, S.; Janoshazi, A.; Procksch, O.; de Barry, J.
F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cells
Exp. Cell Res.
289
222-236
2003
Rattus norvegicus
brenda
Helliwell, P.A.; Rumsby, M.G.; Kellett, G.L.
Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent pathways
J. Biol. Chem.
278
28644-28650
2003
Rattus norvegicus
brenda
Ananthanarayanan, B.; Stahelin, R.V.; Digman, M.A.; Cho, W.
Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains
J. Biol. Chem.
278
46886-46894
2003
Rattus norvegicus
brenda
Ranganathan, S.; Liu, C.X.; Migliorini, M.M.; Von Arnim, C.A.; Peltan, I.D.; Mikhailenko, I.; Hyman, B.T.; Strickland, D.K.
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules
J. Biol. Chem.
279
40536-40544
2004
Homo sapiens, Rattus norvegicus
brenda
Johnson, L.A.; Guptaroy, B.; Lund, D.; Shamban, S.; Gnegy, M.E.
Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta
J. Biol. Chem.
280
10914-10919
2005
Rattus norvegicus
brenda
Tsuda, K.; Tsuda, S.; Nishio, I.
Role of protein kinase C in the regulation of acetylcholine release in the central nervous system of spontaneously hypertensive rats
J. Cardiovasc. Pharmacol.
41 Suppl 1
S57-60
2003
Rattus norvegicus
brenda
Gu, J.L.; Lu, W.; Xia, C.; Wu, X.; Liu, M.
Regulation of hematopoietic-specific G-protein Galpha15 and Galpha16 by protein kinase C
J. Cell. Biochem.
88
1101-1111
2003
Rattus norvegicus
brenda
Bayer, A.L.; Heidkamp, M.C.; Patel, N.; Porter, M.; Engman, S.; Samarel, A.M.
Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy
Mol. Cell. Biochem.
242
145-152
2003
Rattus norvegicus
brenda
Larsen, G.A.; Berg-Johnsen, J.; Moe, M.C.; Vinje, M.L.
Calcium-dependent protein kinase C activation in acutely isolated neurons during oxygen and glucose deprivation
Neurochem. Res.
29
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2004
Rattus norvegicus
brenda
Mahmmoud, Y.A.
Modulation of protein kinase C by curcumin; inhibition and activation switched by calcium ions
Br. J. Pharmacol.
150
200-208
2007
Rattus norvegicus
brenda
Curia, G.; Aracri, P.; Colombo, E.; Scalmani, P.; Mantegazza, M.; Avanzini, G.; Franceschetti, S.
Phosphorylation of sodium channels mediated by protein kinase-C modulates inhibition by topiramate of tetrodotoxin-sensitive transient sodium current
Br. J. Pharmacol.
150
792-797
2007
Rattus norvegicus
brenda
Popp, R.L.; Velasquez, O.; Bland, J.; Hughes, P.
Characterization of protein kinase C isoforms in primary cultured cerebellar granule cells
Brain Res.
1083
70-84
2006
Rattus norvegicus
brenda
Beaudry, H.; Gendron, L.; Guimond, M.O.; Payet, M.D.; Gallo-Payet, N.
Involvement of protein kinase C alpha (PKC alpha) in the early action of angiotensin II type 2 (AT2) effects on neurite outgrowth in NG108-15 cells: AT2-receptor inhibits PKC alpha and p21ras activity
Endocrinology
147
4263-4272
2006
Mus musculus, Rattus norvegicus
brenda
Villanueva-Garcia, D.; Wang, K.T.; Nielsen, H.C.; Ramadurai, S.M.
Expression of specific protein kinase C (PKC) isoforms and ligand-specific activation of PKCalpha in late gestation fetal lung
Exp. Lung Res.
33
185-196
2007
Rattus norvegicus
brenda
Saraiva, L.; Silva, R.D.; Pereira, G.; Goncalves, J.; Corte-Real, M.
Specific modulation of apoptosis and Bcl-xL phosphorylation in yeast by distinct mammalian protein kinase C isoforms
J. Cell Sci.
119
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2006
Mus musculus, Rattus norvegicus
brenda
Nawaratne, R.; Gray, A.; Jorgensen, C.H.; Downes, C.P.; Siddle, K.; Sethi, J.K.
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation
Mol. Endocrinol.
20
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2006
Rattus norvegicus
brenda
Sampson, S.R.; Cooper, D.R.
Specific protein kinase C isoforms as transducers and modulators of insulin signaling
Mol. Genet. Metab.
89
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2006
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Kim, J.Y.; Park, C.S.
Potentiation of large-conductance calcium-activated potassium (BK(Ca)) channels by a specific isoform of protein kinase C
Biochem. Biophys. Res. Commun.
365
459-465
2008
Rattus norvegicus
brenda
Fornes, A.; Nunez, E.; Alonso-Torres, P.; Aragon, C.; Lopez-Corcuera, B.
Trafficking properties and activity regulation of the neuronal glycine transporter GLYT2 by protein kinase C
Biochem. J.
412
495-506
2008
Rattus norvegicus
brenda
Lee, S.; Lynn, E.G.; Kim, J.A.; Quon, M.J.
Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling
Endocrinology
149
2451-2458
2008
Rattus norvegicus (P09217)
brenda
Waraich, R.S.; Weigert, C.; Kalbacher, H.; Hennige, A.M.; Lutz, S.Z.; Haering, H.U.; Schleicher, E.D.; Voelter, W.; Lehmann, R.
Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells
J. Biol. Chem.
283
11226-11233
2008
Rattus norvegicus (P09215)
brenda
Dries, D.R.; Newton, A.C.
Kinetic analysis of the interaction of the C1 domain of protein kinase C with lipid membranes by stopped-flow spectroscopy
J. Biol. Chem.
283
7885-7893
2008
Rattus norvegicus
brenda
Weng, J.Y.; Hsu, T.T.; Sun, S.H.
Functional characterization of P2Y1 versus P2X receptors in RBA-2 astrocytes: elucidate the roles of ATP release and protein kinase C
J. Cell. Biochem.
104
554-567
2008
Rattus norvegicus
brenda
Jajoo, S.; Mukherjea, D.; Brewer, G.J.; Ramkumar, V.
Pertussis toxin B-oligomer suppresses human immunodeficiency virus-1 Tat-induced neuronal apoptosis through feedback inhibition of phospholipase C-beta by protein kinase C
Neuroscience
151
525-532
2008
Rattus norvegicus
brenda
Baldanzi, G.; Alchera, E.; Imarisio, C.; Gaggianesi, M.; Dal Ponte, C.; Nitti, M.; Domenicotti, C.; van Blitterswijk, W.J.; Albano, E.; Graziani, A.; Carini, R.
Negative regulation of diacylglycerol kinase theta mediates adenosine-dependent hepatocyte preconditioning
Cell Death Differ.
17
1059-1068
2010
Rattus norvegicus
brenda
Kwak, H.J.; Park, K.M.; Choi, H.E.; Lim, H.J.; Park, J.H.; Park, H.Y.
The cardioprotective effects of zileuton, a 5-lipoxygenase inhibitor, are mediated by COX-2 via activation of PKC delta
Cell. Signal.
22
80-87
2010
Rattus norvegicus
brenda
Nakamura, K.; Yokotani, K.
Presynaptic BK type Ca(2+)-activated K(+) channels are involved in prostanoid TP receptor-mediated inhibition of noradrenaline release from the rat gastric sympathetic nerves
Eur. J. Pharmacol.
629
111-117
2010
Rattus norvegicus
brenda
Hansson, M.J.; Morota, S.; Teilum, M.; Mattiasson, G.; Uchino, H.; Elmer, E.
Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume
J. Biol. Chem.
285
741-750
2010
Rattus norvegicus
brenda
Parrales, A.; Palma-Nicolas, J.P.; Lopez, E.; Lopez-Colome, A.M.
Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression
J. Cell. Physiol.
222
302-312
2010
Rattus norvegicus
brenda
Jiang, H.; Cheng, D.; Liu, W.; Peng, J.; Feng, J.
Protein kinase C inhibits autophagy and phosphorylates LC3
Biochem. Biophys. Res. Commun.
395
471-476
2010
Rattus norvegicus
brenda
Leonard, T.A.; Rozycki, B.; Saidi, L.F.; Hummer, G.; Hurley, J.H.
Crystal structure and allosteric activation of protein kinase C betaII
Cell
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55-66
2011
Rattus norvegicus
brenda
Martin, T.D.; Mitin, N.; Cox, A.D.; Yeh, J.J.; Der, C.J.
Phosphorylation by protein kinase Calpha regulates RalB small GTPase protein activation, subcellular localization, and effector utilization
J. Biol. Chem.
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2012
Rattus norvegicus
brenda
Vargas-Lopes, C.; Madeira, C.; Kahn, S.A.; Albino do Couto, I.; Bado, P.; Houzel, J.C.; De Miranda, J.; de Freitas, M.S.; Ferreira, S.T.; Panizzutti, R.
Protein kinase C activity regulates D-serine availability in the brain
J. Neurochem.
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2011
Rattus norvegicus
brenda
Williams, A.D.; Jung, S.; Poolos, N.P.
Protein kinase C bidirectionally modulates Ih and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons
J. Physiol.
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2779-2792
2015
Rattus norvegicus
brenda
Cole, T.R.; Igumenova, T.I.
Expression and purification of the N-terminal regulatory domain of protein kinase C for biophysical studies
Protein Expr. Purif.
110
14-21
2015
Rattus norvegicus
brenda
Qvit, N.; Disatnik, M.H.; Sho, E.; Mochly-Rosen, D.
Selective phosphorylation inhibitor of delta protein kinase C-pyruvate dehydrogenase kinase protein-protein interactions Application for myocardial injury in vivo
J. Am. Chem. Soc.
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7626-7635
2016
Rattus norvegicus (P09215)
brenda