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Information on EC 2.7.10.2 - non-specific protein-tyrosine kinase and Organism(s) Homo sapiens and UniProt Accession P23458

for references in articles please use BRENDA:EC2.7.10.2

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IUBMB Comments

Unlike EC 2.7.10.1, receptor protein-tyrosine kinase, this protein-tyrosine kinase does not have a transmembrane domain. In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into ten families .

The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms

Synonyms
bcr-abl, focal adhesion kinase, c-abl, zap-70, src kinase, janus kinase, v-src, ephb4, p56lck, bruton's tyrosine kinase, more

SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tyrosine-protein kinase JAK1
-
70 kDa zeta-associated protein
-
-
-
-
A-Raf proto-oncogene serine/threonine-protein kinase
-
Abelson murine leukemia viral homolog (1) protein
-
-
Abelson tyrosine kinase
-
-
Abl kinase
Abl nonreceptor tyrosine kinase
-
-
Abl protein tyrosine kinase
Abl tyrosine kinase
ABL1 tyrosine kinase
-
ABL2
-
-
ABL2/ARG tyrosine kinase
-
-
activated Cdc42-associated tyrosine kinase 1
-
activin receptor type I
-
activin receptor type II
-
ACTR-IIB
-
-
-
-
ACTRIIA
-
-
-
-
Agammaglobulinaemia tyrosine kinase
-
-
-
-
Amylovoran biosynthesis membrane-associated protein amsA
-
-
-
-
anti-mullerian hormone type II receptor
-
ATK
-
-
-
-
B cell progenitor kinase
-
-
-
-
B lymphocyte kinase
-
-
-
-
B-cell/myeloid kinase
-
-
-
-
B-Raf proto-oncogene serine/threonine-protein kinase
-
BCR-Abl
-
-
Bcr-Abl kinase
-
BCR-ABL tyrosine kinase
BCR/ABL kinase
-
-
Blk kinase
-
BMK
-
-
-
-
BMP type II receptor
-
-
-
-
BMP-2/BMP-4 receptor
-
-
-
-
Bmx tyrosine kinase
-
Bone marrow kinase BMX
-
-
-
-
bone morphogenetic protein receptor type IA
-
bone morphogenetic protein receptor type IB
-
BPK
-
-
-
-
Breast tumor kinase
breast tumour kinase
-
Bruton tyrosine kinase
-
Bruton's tyrosine kinase
Bruton's tyrosine kinase PH domain
-
Brutons tyrosine kinase
BrutonĀ’s tyrosine kinase
-
-
Btk tyrosine kinase
-
-
c-ABL
c-Abl tyrosine kinase
c-FER
-
-
-
-
C-FES
-
-
-
-
c-Fes protein-tyrosine kinase
-
-
c-Fes tyrosine kinase
-
-
C-SRC
C-SRC kinase
c-Src nonreceptor tyrosine kinase
-
-
c-Src protein tyrosine kinase
-
-
c-Src tyrosine kinase
C-terminal Src kinase
-
-
C-YES
CADTK
-
-
-
-
CAK beta
-
-
-
-
Calcium-dependent tyrosine kinase
-
-
-
-
CARD-containing interleukin-1 beta converting enzyme associated kinase
-
Cell adhesion kinase beta
-
-
-
-
Chk tyrosine kinase
-
-
Chk1
-
-
Csk homologous kinase
-
-
Csk protein-tyrosine kinase
-
-
CSK-homologous kinase
-
-
cytoplasmic protein tyrosine kinase
-
-
cytoplasmic tyrosine-protein kinase BMX
-
D-ash
-
-
-
-
DFer
-
-
-
-
Dsrc28C
-
-
-
-
ectoprotein kinase
-
-
-
-
Epithelial and endothelial tyrosine kinase
-
-
-
-
EPS I polysaccharide export protein epsB
-
-
-
-
FADK1
-
-
FADK2
-
-
FAK2
-
-
FER tyrosine kinase
-
Fes tyrosine kinase
-
-
Fgr kinase
-
focal adhesion kinase 1
-
-
-
-
focal adhesion protein tyrosine
-
-
Frk kinase
-
Fyn kinase
-
-
Fyn tyrosine kinase
-
-
fyn-related kinase
-
gene lck protein kinase
-
-
-
-
gene lck tyrosine kinase
-
-
-
-
Hck kinase
-
Hematopoietic consensus tyrosine-lacking kinase
Hemopoietic cell kinase
-
-
-
-
IL-1R-associated kinase
-
IL-2-inducible T-cell kinase
-
-
-
-
integrin-linked protein kinase 1
-
integrin-linked protein kinase 76
-
interleukin-1 receptor-associated kinase 1
-
interleukin-1 receptor-associated kinase-81
-
JAK protein tyrosine kinase
-
-
-
-
Jak tyrosine kinase
-
-
Jak2 protein
-
JAK2 tyrosine kinase
-
-
Janus family kinase JAK3
-
Janus kinase
Janus kinase 1
-
-
Janus kinase 2
just another kinase
-
-
Kinase EMB
-
-
-
-
Kinase EMT
-
-
-
-
Kinase TLK
-
-
-
-
kinase, protein (phosphorylating tyrosine)
-
-
-
-
kinase, protein p56lck (phosphorylating)
-
-
-
-
L-JAK
-
-
-
-
Lck kinase
-
Lck Tyrosine kinase
-
-
-
-
Leukocyte janus kinase
LIM domain kinase 2
-
LSK
-
-
-
-
lymphocyte-specific protein tyrosine kinase
-
-
Lyn tyrosine kinase
-
megakaryocyte-associated tyrosine-protein kinase
-
MIS type II receptor
-
non-receptor protein tyrosine kinase
-
-
non-receptor protein-tyrosine kinase
-
-
non-receptor PTK
-
-
non-receptor tyrosine kinase
-
-
non-receptor tyrosine kinase ABL
-
non-receptor tyrosine kinase brk
-
non-receptor tyrosine-protein kinase TYK2
-
nonreceptor protein tyrosine kinase
-
-
-
-
nonreceptor tyrosine kinase
nonreceptor tyrosine kinase c-Abl
-
nonreceptor tyrosine kinase Fes
-
nonreceptor tyrosine kinase SYK
-
nonreceptor tyrosine kinase Tec
-
NRTK
-
-
NTK38
-
-
-
-
Nuclear tyrosine protein kinase RAK
-
-
-
-
ORF6
-
-
-
-
p135tyk2 tyrosine kinase
-
p150
-
-
-
-
p55-BLK
-
-
-
-
P55-FGR
-
-
-
-
p56-HCK
-
-
-
-
p56-HCK/p59-HCK
-
-
-
-
P56-LCK
-
-
-
-
p56lck kinase
-
-
-
-
p56lck protein kinase
-
-
-
-
p56lck protein tyrosine kinase
-
-
-
-
p56lck tyrosine kinase
-
-
-
-
P57-STK
-
-
-
-
P59-FYN
-
-
-
-
p59-HCK/p60-HCK
-
-
-
-
P60-SRC
-
-
-
-
p60-YRK
-
-
-
-
P61-YES
-
-
-
-
p94-FER
-
-
-
-
phosphotyrosyl-protein kinase
-
-
-
-
PP125FAK
proline-rich tyrosin ekinase 2
-
-
proline-rich tyrosine kinase 2
proline-rich tyrosine kinase-2
-
-
Protein kinase (tyrosine-phosphorylating)
-
-
-
-
protein kinase A
-
-
-
-
Protein kinase BATK
-
-
-
-
Protein kinase HYL
-
-
-
-
Protein kinase Lck
-
-
-
-
Protein kinase NTK
-
-
-
-
Protein kinase p56-LCK
-
-
-
-
Protein kinase p56lck
-
-
-
-
Protein p56c-lck kinase
-
-
-
-
Protein p56lck tyrosine kinase
-
-
-
-
Protein tyrosine kinase
protein tyrosine kinase 2
-
-
protein tyrosine kinase 2beta
-
-
-
-
protein tyrosine kinase 6
-
protein tyrosine kinase 70
-
protein tyrosine kinase focal adhesion kinase
-
-
Protein tyrosine kinase lck
-
-
-
-
Protein tyrosine kinase p56lck
-
-
-
-
Protein tyrosine kinase pp56lck
-
-
-
-
protein-tyrosine kinase
-
-
protein-tyrosine kinase Brk
-
Protein-tyrosine kinase C-TKL
-
-
-
-
Protein-tyrosine kinase CYL
-
-
-
-
Protein-tyrosine kinase Syk
-
-
proto-oncogene serine/threonine-protein kinase mos
-
proto-oncogene tyrosine-protein kinase ABL1
-
proto-oncogene tyrosine-protein kinase FER
-
proto-oncogene tyrosine-protein kinase FES/FPS
-
proto-oncogene tyrosine-protein kinase FYN
-
proto-oncogene tyrosine-protein kinase LCK
-
proto-oncogene tyrosine-protein kinase SRC
-
proto-oncogene tyrosine-protein kinase YES
-
PTK-RL-18
-
-
-
-
PTK6/Sik
-
-
PTK70
Pyk-2
-
-
Quek1
-
-
-
-
RAF proto-oncogene serine/threonine-protein kinase
-
Raf-1 protein kinase
-
Rak tyrosine kinase
-
receptor interacting protein 3
-
receptor-associated kinase JAK2
-
receptor-interacting serine/threonine protein kinase 2
Related adhesion focal tyrosine kinase
-
-
-
-
Resting lymphocyte kinase
-
-
-
-
Rlk/Txk
-
-
-
-
S-domain receptor-like protein kinase
-
-
-
-
serine/threonine-protein kinase receptor R2
-
serine/threonine-protein kinase receptor R3
-
SLK
-
-
-
-
Spleen tyrosine kinase
Src family kinase
-
-
Src kinase
Src protein tyrosine kinase
-
-
src protein tyrosine kinase p56Lck
-
-
Src protein-tyrosine kinase
-
-
Src tyrosine kinase
Src-family protein tyrosine kinase
-
-
src-kinase
-
-
-
-
SRC-related intestinal kinase
-
-
-
-
Syk kinase
-
-
Syk-related tyrosine kinase
-
-
-
-
SYN
-
-
-
-
T cell-specific protein-tyrosine kinase
-
-
-
-
T-cell-specific kinase
-
-
-
-
Tec family tyrosine kinase
-
-
Tec kinase
-
-
testis-specific protein kinase 1
-
testis-specific protein kinase 2
-
TGF-beta receptor type I
-
TGF-beta receptor type II
-
TGF-beta RII
-
transforming growth factor beta type II receptor
-
transforming growth factor-beta type I receptor 7
-
Tyrosine kinase
-
-
-
-
tyrosine kinase 2
-
tyrosine kinase Abl
-
-
Tyrosine kinase ARG
-
-
-
-
tyrosine kinase c-Src
-
-
tyrosine kinase cyl
-
tyrosine kinase Fyn
-
Tyrosine kinase lck
-
-
-
-
Tyrosine kinase p56lck
-
-
-
-
tyrosine kinase p60c-src
-
-
tyrosine kinase PTK6
-
tyrosine kinase Src
-
-
tyrosine kinases src
-
tyrosine kinases yes
-
Tyrosine phosphokinase
-
-
-
-
Tyrosine protein kinase
-
-
-
-
Tyrosine protein kinase p56lck
-
-
-
-
tyrosine-protein kinase 6
-
tyrosine-protein kinase ABL2
-
tyrosine-protein kinase BLK
-
Tyrosine-protein kinase brk
-
-
-
-
tyrosine-protein kinase BTK