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Information on EC 2.7.10.2 - non-specific protein-tyrosine kinase and Organism(s) Homo sapiens and UniProt Accession P12931

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IUBMB Comments
Unlike EC 2.7.10.1, receptor protein-tyrosine kinase, this protein-tyrosine kinase does not have a transmembrane domain. In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into ten families .
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Select one or more organisms in this record:
This record set is specific for:
Homo sapiens
UNIPROT: P12931
Word Map
The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Synonyms
70 kDa zeta-associated protein, A-Raf proto-oncogene serine/threonine-protein kinase, Abelson murine leukemia viral homolog (1) protein, Abelson tyrosine kinase, Abl, Abl kinase, Abl nonreceptor tyrosine kinase, Abl protein tyrosine kinase, Abl tyrosine kinase, ABL1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
70 kDa zeta-associated protein
-
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A-Raf proto-oncogene serine/threonine-protein kinase
266442
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Abelson murine leukemia viral homolog (1) protein
247
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Abelson tyrosine kinase
247
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Abl kinase
Abl nonreceptor tyrosine kinase
247
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Abl protein tyrosine kinase
Abl tyrosine kinase
247
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ABL1 tyrosine kinase
265446
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ABL2
247
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ABL2/ARG tyrosine kinase
247
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activated Cdc42-associated tyrosine kinase 1
298891
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activin receptor type I
266395
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activin receptor type II
266402
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ACTR-IIB
-
-
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ACTRIIA
-
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Agammaglobulinaemia tyrosine kinase
-
-
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AKT
247
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AL
247
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ALK
247
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Amylovoran biosynthesis membrane-associated protein amsA
-
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anti-mullerian hormone type II receptor
266375
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ARG
247
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ATK
-
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B cell progenitor kinase
-
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B lymphocyte kinase
-
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B-cell/myeloid kinase
-
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B-Raf proto-oncogene serine/threonine-protein kinase
266446
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BCR-Abl
247
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Bcr-Abl kinase
265446
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BCR-ABL tyrosine kinase
BCR/ABL kinase
247
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BMK
-
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BMP type II receptor
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BMP-2/BMP-4 receptor
-
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BMPR-IB
266379
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BMPR1A
266373
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Bmx tyrosine kinase
265597
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Bone marrow kinase BMX
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bone morphogenetic protein receptor type IA
266373
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bone morphogenetic protein receptor type IB
266379
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BPK
-
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Breast tumor kinase
breast tumour kinase
265661
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Bruton tyrosine kinase
265722
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Bruton's tyrosine kinase
Bruton's tyrosine kinase PH domain
247
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Brutons tyrosine kinase
Brutonís tyrosine kinase
247
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Btk tyrosine kinase
247
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c-ABL
c-Abl tyrosine kinase
c-FER
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C-FES
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c-Fes protein-tyrosine kinase
247
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c-Fes tyrosine kinase
247
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C-SRC
C-SRC kinase
c-Src nonreceptor tyrosine kinase
247
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c-Src protein tyrosine kinase
247
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c-Src tyrosine kinase
247
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C-terminal Src kinase
247
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C-YES
CADTK
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CAK beta
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Calcium-dependent tyrosine kinase
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CARD-containing interleukin-1 beta converting enzyme associated kinase
266437
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CARDIAK
266437
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Cell adhesion kinase beta
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Chk tyrosine kinase
247
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Chk1
247
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Csk homologous kinase
247
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Csk protein-tyrosine kinase
247
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CSK-homologous kinase
247
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cytoplasmic protein tyrosine kinase
247
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cytoplasmic tyrosine-protein kinase BMX
265597
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D-ash
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DFer
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Dsrc28C
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ectoprotein kinase
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Epithelial and endothelial tyrosine kinase
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EPS I polysaccharide export protein epsB
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ETK
265597
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Etk/BMX
265597
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FADK1
247
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FADK2
247
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FAK2
247
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FER tyrosine kinase
265518
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Fes tyrosine kinase
247
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focal adhesion kinase 1
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focal adhesion protein tyrosine
247
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FPS
247
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Fyn kinase
247
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Fyn tyrosine kinase
247
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fyn-related kinase
265586
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gene lck protein kinase
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gene lck tyrosine kinase
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Hematopoietic consensus tyrosine-lacking kinase
Hemopoietic cell kinase
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hFAK
265739
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HYL
265580
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IL-1R-associated kinase
266421
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IL-2-inducible T-cell kinase
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integrin-linked protein kinase 1
266418
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integrin-linked protein kinase 76
266418
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interleukin-1 receptor-associated kinase 1
266425
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interleukin-1 receptor-associated kinase-81
266421
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IRAK
266425
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IRAK-81
266421
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JAK
247
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JAK protein tyrosine kinase
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Jak tyrosine kinase
247
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Jak2 protein
265442
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JAK2 tyrosine kinase
247
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Janus family kinase JAK3
265599
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Janus kinase
Janus kinase 1
247
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Janus kinase 2
just another kinase
247
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Kinase EMB
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Kinase EMT
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Kinase TLK
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kinase, protein (phosphorylating tyrosine)
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kinase, protein p56lck (phosphorylating)
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L-JAK
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Lck Tyrosine kinase
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Leukocyte janus kinase
LIM domain kinase 2
266428
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LSK
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lymphocyte-specific protein tyrosine kinase
247
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Lyn tyrosine kinase
265478
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MATK
265580
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megakaryocyte-associated tyrosine-protein kinase
265580
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MIS type II receptor
266375
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non-receptor protein tyrosine kinase
247
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non-receptor protein-tyrosine kinase
247
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non-receptor PTK
247
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non-receptor tyrosine kinase
247
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non-receptor tyrosine kinase brk
265661
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non-receptor tyrosine-protein kinase TYK2
265556
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nonreceptor protein tyrosine kinase
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nonreceptor tyrosine kinase
247
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nonreceptor tyrosine kinase Fes
265475
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NRTK
247
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NTK38
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Nuclear tyrosine protein kinase RAK
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ORF6
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p135tyk2 tyrosine kinase
265556
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p150
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p55-BLK
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P55-FGR
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p56-HCK
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p56-HCK/p59-HCK
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P56-LCK
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p56lck kinase
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p56lck protein kinase
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p56lck protein tyrosine kinase
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p56lck tyrosine kinase
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P57-STK
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P59-FYN
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p59-HCK/p60-HCK
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P60-SRC
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p60-YRK
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P61-YES
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p94-FER
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phosphotyrosyl-protein kinase
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PP125FAK
proline-rich tyrosin ekinase 2
247
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proline-rich tyrosine kinase 2
proline-rich tyrosine kinase-2
247
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Protein kinase (tyrosine-phosphorylating)
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protein kinase A
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Protein kinase BATK
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Protein kinase HYL
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Protein kinase Lck
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Protein kinase NTK
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Protein kinase p56-LCK
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Protein kinase p56lck
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Protein p56c-lck kinase
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Protein p56lck tyrosine kinase
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Protein tyrosine kinase
protein tyrosine kinase 2
247
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protein tyrosine kinase 2beta
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protein tyrosine kinase 6
265661
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protein tyrosine kinase focal adhesion kinase
247
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Protein tyrosine kinase lck
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Protein tyrosine kinase p56lck
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Protein tyrosine kinase pp56lck
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protein-tyrosine kinase
247
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protein-tyrosine kinase Brk
265661
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Protein-tyrosine kinase C-TKL
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Protein-tyrosine kinase CYL
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Protein-tyrosine kinase Syk
247
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proto-oncogene serine/threonine-protein kinase mos
266415
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proto-oncogene tyrosine-protein kinase ABL1
265446
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proto-oncogene tyrosine-protein kinase FER
265518
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proto-oncogene tyrosine-protein kinase FES/FPS
265475
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proto-oncogene tyrosine-protein kinase FYN
265473
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proto-oncogene tyrosine-protein kinase LCK
265711
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proto-oncogene tyrosine-protein kinase SRC
265497
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proto-oncogene tyrosine-protein kinase YES
265477
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PTK-RL-18
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PTK2B
265743
gene name
PTK6
265661
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PTK6/Sik
247
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PTK70
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Pyk-2
247
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Quek1
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RAF proto-oncogene serine/threonine-protein kinase
266439
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Raf-1 protein kinase
266439
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Rak tyrosine kinase
265586
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receptor interacting protein 3
266451
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receptor-associated kinase JAK2
265442
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receptor-interacting serine/threonine protein kinase 2
Related adhesion focal tyrosine kinase
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Resting lymphocyte kinase
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RIP2
266437
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Rlk/Txk
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S-domain receptor-like protein kinase
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serine/threonine-protein kinase receptor R2
266388
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serine/threonine-protein kinase receptor R3
266381
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SLK
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Spleen tyrosine kinase
Src family kinase
247
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Src kinase
247
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Src protein tyrosine kinase
247
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src protein tyrosine kinase p56Lck
247
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Src protein-tyrosine kinase
247
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Src tyrosine kinase
Src-family protein tyrosine kinase
247
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src-kinase
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SRC-related intestinal kinase
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Srm
247
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Syk kinase
247
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Syk-related tyrosine kinase
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SYN
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T cell-specific protein-tyrosine kinase
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T-cell-specific kinase
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Tec family tyrosine kinase
247
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Tec kinase
247
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TESK1
266430
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TESK2
266434
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testis-specific protein kinase 1
266430
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testis-specific protein kinase 2
266434
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TFK
247
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TGF-beta receptor type I
266378
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TGF-beta receptor type II
266372
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TGF-beta RII
266372
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TGFBR1
266378
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TNK2
298891
gene name
transforming growth factor beta type II receptor
266372
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transforming growth factor-beta type I receptor 7
266378
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TYK-2
265556
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TYK3
265518
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Tyrosine kinase
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tyrosine kinase 2
265556
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tyrosine kinase Abl
247
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Tyrosine kinase ARG
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tyrosine kinase c-Src
247
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tyrosine kinase cyl
265575
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Tyrosine kinase lck
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Tyrosine kinase p56lck
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tyrosine kinase p60c-src
247
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tyrosine kinase PTK6
265661
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tyrosine kinase Src
247
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Tyrosine phosphokinase
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Tyrosine protein kinase
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Tyrosine protein kinase p56lck
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tyrosine-protein kinase 6
265661
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tyrosine-protein kinase ABL2
265585
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tyrosine-protein kinase BLK
265596
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Tyrosine-protein kinase brk
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tyrosine-protein kinase BTK
265722
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tyrosine-protein kinase CSK
265575
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Tyrosine-protein kinase CTK
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-
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tyrosine-protein kinase FRK
265586
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tyrosine-protein kinase ITK/TSK
265657
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tyrosine-protein kinase JAK1
265536
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tyrosine-protein kinase JAK2
265442
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tyrosine-protein kinase JAK3
265599
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Tyrosine-protein kinase Lyk
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-
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tyrosine-protein kinase LYN
265478
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tyrosine-protein kinase SYK
265592
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tyrosine-protein kinase Tec
265581
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tyrosine-protein kinase TXK
265582
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Tyrosine-protein kinase TYRO 10
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tyrosine-protein kinase ZAP-70
265590
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Tyrosine-specific protein kinase
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Tyrosylprotein kinase
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-
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v-fps Protein-tyrosine kinase
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WEE1hu
YES related kinase
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-
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YES1
265477
gene name
yrk
247
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ZAP-70
247
-
additional information
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
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phospho group transfer
PATHWAY SOURCE
PATHWAYS