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IUBMB CommentsAlso acts on streptamine, 2-deoxystreptamine and 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol.
The enzyme appears in viruses and cellular organisms
Synonyms
ATP:inosamine phosphotransferase, kinase, scyllo-inosamine (phosphorylating), scyllo-inosamine kinase,
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ATP:inosamine phosphotransferase
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kinase, scyllo-inosamine (phosphorylating)
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scyllo-inosamine kinase
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ATP + 1-amino-1-deoxy-scyllo-inositol = ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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phospho group transfer
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ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase
Also acts on streptamine, 2-deoxystreptamine and 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol.
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2'-deoxy-ATP + scyllo-inosamine
2'-deoxy-ADP + scyllo-inosamine phosphate
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
ATP + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol
1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate + ADP
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ATP + 2-deoxystreptamine
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ATP + scyllo-inosamine
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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reaction involved in biosynthesis of streptidine from myo-inositol
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ATP + streptamine
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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no activity with streptidine, myoinosamine-2, DL-myoinosamine-4 and neoinosamine-2
scyllo-inosamine-phosphate
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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no activity with guanidinodeoxy-scyllo-inositol
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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no activity with CTP, UTP, dTTP or GTP
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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i.e. scyllo-inosamine
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ATP + 1-amino-1-deoxy-scyllo-inositol
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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i.e. scyllo-inosamine
scyllo-inosamine-phosphate
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ATP + scyllo-inosamine
ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate
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reaction involved in biosynthesis of streptidine from myo-inositol
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Mg2+
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required for activity
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p-chloromercuribenzoate
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ATCC 11062
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ATCC 12475
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A0A7W7PXV2_9ACTN
308
0
33485
TrEMBL
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A0A7X0GLD9_9ACTN
330
0
35535
TrEMBL
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A0A852Z6T3_9ACTN
323
0
35291
TrEMBL
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A0A7W8QI58_9ACTN
257
0
27846
TrEMBL
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A0A7X0NTX3_9ACTN
308
0
32585
TrEMBL
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A0A841G486_9ACTN
325
0
34593
TrEMBL
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mercaptan required during purification
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purified enzyme preparations are stabilized by addition of serum albumin and mercaptans
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ammonium sulfate, Sephadex G-100 or DEAE-cellulose
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Walker, J.B.; Walker, M.S.
Enzymatic synthesis of streptidine from scyllo-inosamine
Biochemistry
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3821-3829
1967
Streptomyces bikiniensis, Streptomyces griseus
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Walker, J.B.
ATP:inosamine phosphotransferase(s)
Methods Enzymol.
43
444-451
1975
Streptomyces bikiniensis
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2.7.1.65 scyllo-inosamine 4-kinase
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