Disease on EC 2.7.1.64 - inositol 3-kinase
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DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma of Lung
Alternate paths from epidermal growth factor receptor to Akt in malignant versus nontransformed lung epithelial cells: ErbB3 versus Gab1.
Breast Neoplasms
MICAL1 facilitates breast cancer cell proliferation via ROS-sensitive ERK/cyclin D pathway.
Breast Neoplasms
Phosphatidyl inositol 3-kinase (PI3K)-mTOR inhibitor PKI-402 inhibits breast cancer induced osteolysis.
Breast Neoplasms
Targeting the Phosphatidyl Inositol 3-Kinase Signaling Pathway in Breast Cancer.
Breast Neoplasms
The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer.
Carcinogenesis
Inhibition of midkine by metformin can contribute to its anticancer effects in malignancies: A proposal mechanism of action of metformin in context of endometrial cancer prevention and therapy.
Colorectal Neoplasms
FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma.
Diabetes Mellitus, Type 1
Tuning in to the "right" calcium channel regulation in experimental models of diabetes.
Encephalomyelitis
Suppression of CD4+ T lymphocyte activation in vitro and experimental encephalomyelitis in vivo by the phosphatidyl inositol 3-kinase inhibitor PIK-75.
Fetal Growth Retardation
[Study on the mechanism of insulin resistance in rats born with intrauterine growth retardation]
Infections
Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.
Insulin Resistance
The Mechanism by Which Amentoflavone Improves Insulin Resistance in HepG2 Cells.
Insulin Resistance
[Study on the mechanism of insulin resistance in rats born with intrauterine growth retardation]
Lymphoma
B-cell activating factor-receptor specific activation of tumor necrosis factor receptor associated factor 6 and the phosphatidyl inositol 3-kinase pathway in lymphoma B cells.
Lymphoma
Exosomes from Dendritic Cells Loaded with Chaperone-Rich Cell Lysates Elicit a Potent T Cell Immune Response Against Intracranial Glioma in Mice.
Lymphoma
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members.
Lymphoma, B-Cell
Shikonin inhibits TNF-?-induced growth and invasion of rat aortic vascular smooth muscle cells.
Lymphoma, B-Cell
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members.
Melanoma
The phosphatidyl inositol 3-kinase pathway is central to the pathogenesis of Kit-activated melanoma.
Neoplasms
?-Estradiol Enhanced Secretion of Lipoprotein Lipase from Mouse Mammary Tumor FM3A Cells.
Neoplasms
Association between Genetic and Immunological Background of Hepatocellular Carcinoma and Expression of Programmed Cell Death-1.
Neoplasms
B-cell activating factor-receptor specific activation of tumor necrosis factor receptor associated factor 6 and the phosphatidyl inositol 3-kinase pathway in lymphoma B cells.
Neoplasms
Differential radio-adaptive responses in BALB/c and C57BL/6 mice: pivotal role of calcium and nitric oxide signalling.
Neoplasms
Expression, localization, and phosphorylation of Akt1 in benign and malignant thyroid lesions.
Neoplasms
Influence of hepatic artery occlusion on tumor growth and metastatic potential in a human orthotopic hepatoma nude mouse model: Relevance of epithelial-mesenchymal transition.
Neoplasms
Inhibition of midkine by metformin can contribute to its anticancer effects in malignancies: A proposal mechanism of action of metformin in context of endometrial cancer prevention and therapy.
Neoplasms
INPP4B exerts a dual function in the stemness of colorectal cancer stem-like cells through regulating Sox2 and Nanog expression.
Neoplasms
INPP4B inhibits cell proliferation, invasion and chemoresistance in human hepatocellular carcinoma.
Neoplasms
Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.
Neoplasms
Quercetin enhances susceptibility to NK cell-mediated lysis of tumor cells through induction of NKG2D ligands and suppression of HSP70.
Neoplasms
Using Molecular Docking Analysis to Discovery Dregea sinensis Hemsl. Potential Mechanism of Anticancer, Antidepression, and Immunoregulation.
Neoplasms
Wortmannin induces MCF-7 breast cancer cell death via the apoptotic pathway, involving chromatin condensation, generation of reactive oxygen species, and membrane blebbing.
Osteolysis
Phosphatidyl inositol 3-kinase (PI3K)-mTOR inhibitor PKI-402 inhibits breast cancer induced osteolysis.
Osteosarcoma
Long non-coding RNA CCAT1/miR-148a axis promotes osteosarcoma proliferation and migration through regulating PIK3IP1.
Ovarian Neoplasms
[Effects of PTEN over-expression on phosphatidyl inositol 3-kinase/protein kinase B signal pathway in ovarian epithelial cancer cells].
Prostatic Neoplasms
The role of fibroblast growth factors and their receptors in prostate cancer.
Status Epilepticus
Expression of Bcl-2 and Bad in hippocampus of status epileptic rats and molecular mechanism of intervened recombinant human erythropoietin.
Thymoma
FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma.
Thyroid Neoplasms
Suppressor of cytokine signaling 3 sensitizes anaplastic thyroid cancer to standard chemotherapy.
Triple Negative Breast Neoplasms
[Molecular mechanisms of resistance to phosphatidyl inositol 3-kinase inhibitors in triple-negative breast cancer cells].
Tuberculosis
Regulation of matrix metalloproteinase-1, -3, and -9 in Mycobacterium tuberculosis-dependent respiratory networks by the rapamycin-sensitive PI3K/p70S6K cascade.
Whooping Cough
Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion.
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