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Information on EC 2.7.1.223 - aminoimidazole riboside kinase

for references in articles please use BRENDA:EC2.7.1.223

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IUBMB Comments

The enzyme, characterized from the bacterium Salmonella enterica, can phosphorylate exogeneously-provided 5-amino-1-(β-D-ribosyl)imidazole to form 5-amino-1-(5-phospho-β-D-ribosyl)imidazole (AIR), an important intermediate in the production of both purine mononucleotides and the hydroxymethyl pyrimidine moiety of thiamine.

The enzyme appears in viruses and cellular organisms

Synonyms
stm4066, aminoimidazole riboside kinase, vca0656, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 5-amino-1-(beta-D-ribosyl)imidazole = ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
show the reaction diagram
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