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Information on EC 2.7.1.22 - ribosylnicotinamide kinase and Organism(s) Saccharomyces cerevisiae and UniProt Accession P53915

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Saccharomyces cerevisiae
UNIPROT: P53915 not found.
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The taxonomic range for the selected organisms is: Saccharomyces cerevisiae
The enzyme appears in selected viruses and cellular organisms
Synonyms
nicotinamide riboside kinase, nmrk2, nrk-2, ribosylnicotinamide kinase, nicotinamide riboside kinase 2, nmrk1, nrk2b, nicotinamide riboside kinase 1, nmr-k, nicotinamide ribose kinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nicotinamide riboside kinase
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kinase, ribosylnicotinamide (phosphorylating)
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
ATP:N-ribosylnicotinamide 5'-phosphotransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9030-61-9
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + N-ribosylnicotinamide
ADP + nicotinamide ribonucleotide
show the reaction diagram
nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
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-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + N-ribosylnicotinamide
ADP + nicotinamide ribonucleotide
show the reaction diagram
nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Belenky, P.; Racette, F.G.; Bogan, K.L.; McClure, J.M.; Smith, J.S.; Brenner, C.
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
Cell
129
473-484
2007
Saccharomyces cerevisiae (P53915)
Manually annotated by BRENDA team