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IUBMB CommentsThe enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.
The taxonomic range for the selected organisms is: Mycolicibacterium smegmatis
The enzyme appears in selected viruses and cellular organisms
Synonyms
L-erythrulose 4-kinase,
lerK,
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L-erythrulose 4-kinase
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ATP:L-erythrulose 1-phosphotransferase
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol.
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ATP + D-erythrulose
ADP + D-erythrulose 4-phosphate
catalytic efficiency is 4fold lower compared to L-erythrulose as substrate
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ATP + dihydroxyacetone
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catalytic efficiency is about 100fold lower compared to L-erythrulose as substrate
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
the enzyme participates in the degradation of L-threitol
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ATP + L-erythrulose
ADP + L-erythrulose 4-phosphate
the enzyme participates in the degradation of L-threitol
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0.0106
D-erythrulose
pH and temperature not specified in the publication
0.0378
dihydroxyacetone
pH and temperature not specified in the publication
0.003
L-erythrulose
pH and temperature not specified in the publication
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1.6
D-erythrulose
pH and temperature not specified in the publication
2.12
dihydroxyacetone
pH and temperature not specified in the publication
1.79
L-erythrulose
pH and temperature not specified in the publication
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150.9
D-erythrulose
pH and temperature not specified in the publication
56.1
dihydroxyacetone
pH and temperature not specified in the publication
597
L-erythrulose
pH and temperature not specified in the publication
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SwissProt
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metabolism
the enzyme participates in the degradation of L-threitol
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Huang, H.; Carter, M.S.; Vetting, M.W.; Al-Obaidi, N.; Patskovsky, Y.; Almo, S.C.; Gerlt, J.A.
A general strategy for the discovery of metabolic pathways: D-threitol, L-threitol, and erythritol utilization in Mycobacterium smegmatis
J. Am. Chem. Soc.
137
14570-14573
2015
Mycolicibacterium smegmatis (A0R758)
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