show all | hide all No of entries

Information on EC - protein-Npi-phosphohistidine-2-O-alpha-mannosyl-D-glycerate phosphotransferase

for references in articles please use BRENDA:EC2.7.1.195
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
Specify your search results
Select one or more organisms in this record:
The expected taxonomic range for this enzyme is: Escherichia coli
2-O-alpha-mannosyl-D-glycerate PTS permease, EIImannosylglycerate, EIIMngA, Frx, HrsA, IIHrsA, IIMngA, mngA, more
[protein]-Npi-phospho-L-histidine + 2-O-(alpha-D-mannopyranosyl)-D-glycerate [side 1] = [protein]-L-histidine + 2-O-(6-phospho-alpha-D-mannopyranosyl)-D-glycerate [side 2]
show the reaction diagram
Select items on the left to see more content.