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Information on EC 2.7.1.185 - mevalonate 3-kinase

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IUBMB Comments
Mevalonate 3-kinase and mevalonate-3-phosphate-5-kinase (EC 2.7.1.186) act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum. Mevalonate 3-kinase is different from mevalonate kinase, EC 2.7.1.36, which transfers phosphate to position 5 of (R)-mevalonate and is part of the classical mevalonate pathway in eukaryotes and archaea.
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The enzyme appears in viruses and cellular organisms
Synonyms
ATP:(R)-MVA 3-phosphotransferase, M3K, PTO1356, Ta1305, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + (R)-mevalonate = ADP + (R)-3-phosphomevalonate
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