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Information on EC 2.7.1.17 - xylulokinase
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2.7.1.17 xylulokinaseSpecify your search results
Word Map
- 2.7.1.17
- xylose
- xylitol
-
mcleod
- pentose
- stipitis
-
lignocellulosic
-
x-linked
-
xylose-fermenting
- acanthocytosis
- neuroacanthocytosis
-
xylose-utilizing
- l-arabinose
- transaldolase
-
xylose-metabolizing
-
xylazine
-
co-fermentation
-
acanthocyte
-
xylulose-5-phosphate
-
bioethanol
- chorea-acanthocytosis
- biotechnology
- synthesis
The enzyme appears in viruses and cellular organisms
Synonyms
xk, xylulokinase, d-xylulokinase, d-xylulose kinase, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
ATP/polyphosphate xylulokinase
D-xylulokinase
Huta_2446
kinase (phosphorylating), xylulo
-
-
-
-
kinase, xylulo- (phosphorylating)
-
-
-
-
TM0116
XK
-
-
-
-
XKS1
XYL3
XylB
xylokinase(phosphorylating)
-
-
-
-
xylulokinase
D-xylulokinase
-
-
-
-
xylulokinase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
ATP + D-xylulose = ADP + D-xylulose 5-phosphate
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
phospho group transfer
-
-
-
-
Phosphorylation
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
ATP:D-xylulose 5-phosphotransferase
-
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CAS REGISTRY NUMBER
COMMENTARY
9030-58-4
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + D-xylitol
ADP + ?
121% relative activity compared to D-glucose
-
-
?
ATP + D-xylitol
ADP + D-xylitol-1-phosphate
-
analyzed with 31P NMR spectrum
-
-
?
ATP + D-xylose
ADP + D-xylose 5-phosphate
85% relative activity compared to D-glucose
-
-
?
ATP + L(-)-arabitol
ADP + L(-)-arabitol 5-phosphate
93% relative activity compared to D-glucose
-
-
?
ATP + L-arabinose
ADP + L-arabinose 5-phosphate
96% relative activity compared to D-glucose
-
-
?
ATP + L-erythrulose
ADP + ?
-
phosphorylation at 30% the rate of D-xylulose
-
-
?
ATP + ribitol
ADP + ?
41% relative activity compared to D-glucose
-
-
?
GTP + 1-deoxy-D-xylulose
GDP + 1-deoxy-D-xylulose 5-phosphate
-
38% of the activity with ATP
-
?
ITP + 1-deoxy-D-xylulose
IDP + 1-deoxy-D-xylulose 5-phosphate
-
26% of the activity with ATP
-
?
ITP + D-xylulose
IDP + D-xylulose 5-phosphate
-
phosphorylation at 25% the rate of ATP
-
-
?
(polyphosphate)n + D-xylulose
(polyphosphate)n-1 + D-xylulose 5-phosphate
activity with polyphosphate is 41 % of its specific activity on ATP
-
-
?
(polyphosphate)n + D-xylulose
(polyphosphate)n-1 + D-xylulose 5-phosphate
activity with polyphosphate is 41 % of its specific activity on ATP
-
-
?
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
-
-
?
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
the reaction constitutes a potential salvage pathway for the generation of 1-deoxy-D-xylulose 5-phosphate from exogenous or endogenous 1-deoxy-D-xylulose as starting material for the biosynthesis of terpenoids, thiamine and pyridoxal
-
?
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
-
-
?
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
the reaction constitutes a potential salvage pathway for the generation of 1-deoxy-D-xylulose 5-phosphate from exogenous or endogenous 1-deoxy-D-xylulose as starting material for the biosynthesis of terpenoids, thiamine and pyridoxal
-
?
ATP + D(+)-arabitol
ADP + D(+)-arabitol 5-phosphate
76% relative activity compared to D-glucose
-
-
?
ATP + D(+)-arabitol
ADP + D(+)-arabitol 5-phosphate
76% relative activity compared to D-glucose
-
-
?
ATP + D(-)-arabinose
ADP + D(-)arabinose 5-phosphate
97% relative activity compared to D-glucose
-
-
?
ATP + D(-)-arabinose
ADP + D(-)arabinose 5-phosphate
97% relative activity compared to D-glucose
-
-
?
ATP + D-fructose
ADP + D-fructose 5-phosphate
-
-
-
?
ATP + D-ribose
ADP + D-ribose 5-phosphate
85% relative activity compared to D-glucose
-
-
?
ATP + D-ribose
ADP + D-ribose 5-phosphate
85% relative activity compared to D-glucose
-
-
?
ATP + D-ribulose
ADP + D-ribulose 5-phosphate
-
60% of the activity with D-xylulose
-
-
?
ATP + D-ribulose
ADP + D-ribulose 5-phosphate
-
60% of the activity with D-xylulose
-
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
intracellular xylitol is partly converted to xylitol-5-phosphate by xylulokinase
-
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
-
-
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
intracellular xylitol is partly converted to xylitol-5-phosphate by xylulokinase
-
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
-
analyzed with 31P NMR spectrum
-
-
?
ATP + D-xylulose
?
-
enzyme of ribitol catabolism, inducible by ribitol
-
-
?
ATP + D-xylulose
?
-
overexpression of xylulokinase in Saccharomyces cerevisiae is detrimental to cell growth on xylulose but not on glucose
-
-
?
ATP + D-xylulose
?
-
xylulokinase activity is absent during glucose metabolism but is detectable during simultaneous utilization of xylulose and glucose
-
-
?
ATP + D-xylulose
?
-
expression level of xylulokinase can limit xylulose metabolism, although other factors are also likely to have a role
-
-
?
ATP + D-xylulose
?
-
the enzyme is involved in one of the initial steps of xylose utilization
-
-
?
ATP + D-xylulose
?
-
expression level of xylulokinase can limit xylulose metabolism, although other factors are also likely to have a role
-
-
?
ATP + D-xylulose
?
-
overexpression of xylulokinase in Saccharomyces cerevisiae is detrimental to cell growth on xylulose but not on glucose
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
L-Ribulose is not phosphorylated at significant rates
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
L-Ribulose is not phosphorylated at significant rates
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
specific for D-isomer
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
specific for D-isomer
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
specific for D-isomer
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
r
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
specific for D-isomer
-
r
ATP + L-ribulose
ADP + L-ribulose 5-phosphate
3.8% of the activity with D-xylulose
-
-
?
ATP + L-ribulose
ADP + L-ribulose 5-phosphate
3.8% of the activity with D-xylulose
-
-
?
ATP + L-xylulose
ADP + L-xylulose 5-phosphate
57.6% of the activity with D-xylulose
-
-
?
ATP + L-xylulose
ADP + L-xylulose 5-phosphate
57.6% of the activity with D-xylulose
-
-
?
CTP + 1-deoxy-D-xylulose
CDP + 1-deoxy-D-xylulose 5-phosphate
-
18% of the activity with ATP
-
?
CTP + 1-deoxy-D-xylulose
CDP + 1-deoxy-D-xylulose 5-phosphate
-
18% of the activity with ATP
-
?
GTP + D-xylulose
GDP + D-xylulose 5-phosphate
-
phosphorylation at 25% the rate of ATP
-
-
?
UTP + 1-deoxy-D-xylulose
UDP + 1-deoxy-D-xylulose 5-phosphate
-
8% of the activity with ATP
-
?
UTP + 1-deoxy-D-xylulose
UDP + 1-deoxy-D-xylulose 5-phosphate
-
8% of the activity with ATP
-
?
UTP + D-xylulose
UDP + D-xylulose 5-phosphate
-
phosphorylation at 14% the rate of ATP
-
-
?
UTP + D-xylulose
UDP + D-xylulose 5-phosphate
-
15% of the activity with ATP
-
-
?
additional information
?
-
no activity with D-xylose
-
-
?
additional information
?
-
-
no activity with D-xylose
-
-
?
additional information
?
-
-
enzyme is constitutively expressed
-
-
?
additional information
?
-
-
enzyme expression is not rate-limiting for xylose metabolism
-
-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
the reaction constitutes a potential salvage pathway for the generation of 1-deoxy-D-xylulose 5-phosphate from exogenous or endogenous 1-deoxy-D-xylulose as starting material for the biosynthesis of terpenoids, thiamine and pyridoxal
-
?
ATP + 1-deoxy-D-xylulose
ADP + 1-deoxy-D-xylulose 5-phosphate
-
the reaction constitutes a potential salvage pathway for the generation of 1-deoxy-D-xylulose 5-phosphate from exogenous or endogenous 1-deoxy-D-xylulose as starting material for the biosynthesis of terpenoids, thiamine and pyridoxal
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
intracellular xylitol is partly converted to xylitol-5-phosphate by xylulokinase
-
-
?
ATP + D-xylitol
ADP + D-xylitol-5-phosphate
intracellular xylitol is partly converted to xylitol-5-phosphate by xylulokinase
-
-
?
ATP + D-xylulose
?
-
enzyme of ribitol catabolism, inducible by ribitol
-
-
?
ATP + D-xylulose
?
-
overexpression of xylulokinase in Saccharomyces cerevisiae is detrimental to cell growth on xylulose but not on glucose
-
-
?
ATP + D-xylulose
?
-
xylulokinase activity is absent during glucose metabolism but is detectable during simultaneous utilization of xylulose and glucose
-
-
?
ATP + D-xylulose
?
-
expression level of xylulokinase can limit xylulose metabolism, although other factors are also likely to have a role
-
-
?
ATP + D-xylulose
?
-
the enzyme is involved in one of the initial steps of xylose utilization
-
-
?
ATP + D-xylulose
?
-
expression level of xylulokinase can limit xylulose metabolism, although other factors are also likely to have a role
-
-
?
ATP + D-xylulose
?
-
overexpression of xylulokinase in Saccharomyces cerevisiae is detrimental to cell growth on xylulose but not on glucose
-
-
?
ATP + D-xylulose
ADP + D-xylulose 5-phosphate
-
-
-
?
additional information
?
-
-
enzyme is constitutively expressed
-
-
?
additional information
?
-
-
enzyme expression is not rate-limiting for xylose metabolism
-
-
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Fe2+
Mg2+
Mn2+
Zn2+
Mg2+