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Information on EC 2.7.1.164 - O-phosphoseryl-tRNASec kinase

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IUBMB Comments
In archaea and eukarya selenocysteine formation is achieved by a two-step process: O-phosphoseryl-tRNASec kinase (PSTK) phosphorylates the endogenous L-seryl-tRNASec to O-phospho-L-seryl-tRNASec, and then this misacylated amino acid-tRNA species is converted to L-selenocysteinyl-tRNASec by EC 2.9.1.2 (Sep-tRNA:Sec-tRNA synthase).
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The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Reaction Schemes
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O-phospho-L-seryl-tRNASec
Synonyms
o-phosphoseryl-trna(sec) kinase, o-phosphoseryl-trna kinase, phosphoseryl-trna[ser]sec kinase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + L-seryl-tRNASec = ADP + O-phospho-L-seryl-tRNASec
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