Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 2.7.1.138 - ceramide kinase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
Control of Skeletal Muscle Atrophy Associated to Cancer or Corticosteroids by Ceramide Kinase.
Adenocarcinoma of Lung
Activation of ceramidase and ceramide kinase by vanadate via a tyrosine kinase-mediated pathway.
Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells.
Asthma
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Atherosclerosis
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Breast Neoplasms
Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt.
Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple-negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways.
Ceramide kinase promotes tumor cell survival and mammary tumor recurrence.
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.
Carcinoma
Control of Skeletal Muscle Atrophy Associated to Cancer or Corticosteroids by Ceramide Kinase.
Carcinoma, Lewis Lung
Control of Skeletal Muscle Atrophy Associated to Cancer or Corticosteroids by Ceramide Kinase.
ceramide kinase deficiency
Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro.
Ceramide kinase deficiency improves diet-induced obesity and insulin resistance.
Colitis
Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis.
Cone-Rod Dystrophies
Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene.
Hypersensitivity
Effect of eriodictyol on the development of atopic dermatitis-like lesions in ICR mice.
Hypersensitivity, Immediate
Effect of eriodictyol on the development of atopic dermatitis-like lesions in ICR mice.
Infections
Loss of ceramide kinase in Arabidopsis impairs defenses and promotes ceramide accumulation and mitochondrial H2O2 bursts.
Insulin Resistance
Ceramide kinase deficiency improves diet-induced obesity and insulin resistance.
Serum Ceramide Kinase as a Biomarker of Cognitive Functions, and the Effect of Using Two Slimming Dietary Therapies in Obese Middle Aged Females.
Leukemia
Ceramide kinase expression is altered during macrophage-like cell differentiation of the leukemia cell line HL-60.
Characterization of a ceramide kinase activity from human leukemia (HL-60) cells. Separation from diacylglycerol kinase activity.
Lung Neoplasms
Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death.
Muscular Atrophy
Control of Skeletal Muscle Atrophy Associated to Cancer or Corticosteroids by Ceramide Kinase.
Neoplasm Metastasis
Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
Neoplasms
Alteration of Ceramide 1-O-Functionalization as a Promising Approach for Cancer Therapy.
Ceramide kinase promotes tumor cell survival and mammary tumor recurrence.
Ceramide kinase regulates the production of tumor necrosis factor ? (TNF?) via inhibition of TNF?-converting enzyme.
Control of Skeletal Muscle Atrophy Associated to Cancer or Corticosteroids by Ceramide Kinase.
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Regulation of cell growth, survival and migration by ceramide 1-phosphate - implications in lung cancer progression and inflammation.
The Role of Ceramide 1-Phosphate in Tumor Cell Survival and Dissemination.
Neuroblastoma
ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells: the role of COUP-TFI.
Ceramide kinase regulates TNF?-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells.
New signalling pathway involved in the anti-proliferative action of vitamin D? and its analogues in human neuroblastoma cells. A role for ceramide kinase.
Obesity
Ceramide kinase deficiency improves diet-induced obesity and insulin resistance.
Serum Ceramide Kinase as a Biomarker of Cognitive Functions, and the Effect of Using Two Slimming Dietary Therapies in Obese Middle Aged Females.
Pancreatic Neoplasms
Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells.
Respiratory Hypersensitivity
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Retinal Degeneration
Hyperautofluorescent Dots are Characteristic in Ceramide Kinase Like-associated Retinal Degeneration.
Retinitis Pigmentosa
Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene.
Identification of a nuclear localization signal in the retinitis pigmentosa-mutated RP26 protein, ceramide kinase-like protein.
Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26).
Starvation
Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells.
Thrombosis
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Triple Negative Breast Neoplasms
Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple-negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways.