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The taxonomic range for the selected organisms is: Caenorhabditis elegans
The enzyme appears in selected viruses and cellular organisms
Synonyms
pi3k, phosphatidylinositol 3-kinase, pi3 kinase, vps34, phosphoinositide-3-kinase, phosphatidylinositol 3 kinase, ptdins 3-kinase, pik3c3, phosphatidylinositide 3-kinase, hvps34,
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kinase (phosphorylating), phosphatidylinositol 3-
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kinase, phosphatidylinositol 3- (phosphorylating)
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p85/p110 phosphoinositide 3-kinase
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phosphatidylinositol 3'-kinase
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phosphatidylinositol 3-kinase
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phosphoinositide 3'-kinase
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phosphoinositide 3-kinase
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phospho group transfer
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ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
One mammalian isoform is known.
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ATP + 1-phosphatidylinositol
ADP + phosphatidylinositol 3-phosphate
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ATP + 1-phosphatidylinositol
ADP + phosphatidylinositol 3-phosphate
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additional information
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regulating longevity and diapause
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additional information
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regulating longevity and diapause
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SwissProt
brenda
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AGE1_CAEEL
1182
0
136873
Swiss-Prot
Mitochondrion (Reliability: 3)
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Vanhaesebroeck, B.; Leevers, S.J.; Ahmadi, K.; Timms, J.; Katso, R.; Driscoll, P.C.; Woscholski, R.; Parker, P.J.; Waterfield, M.D.
Synthesis and function of 3-phosphorylated inositol lipids
Annu. Rev. Biochem.
70
535-602
2001
Caenorhabditis elegans, Dictyostelium discoideum, Drosophila melanogaster
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Morris, J.Z.; Tissenbaum, H.A.; Ruvkun, G.
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
Nature
382
536-539
1996
Caenorhabditis elegans (Q94125)
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