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Information on EC 2.7.1.1 - hexokinase and Organism(s) Oryza sativa and UniProt Accession Q2KNB7

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EC Tree
IUBMB Comments
D-Glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase.
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This record set is specific for:
Oryza sativa
UNIPROT: Q2KNB7
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Word Map
The taxonomic range for the selected organisms is: Oryza sativa
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
hexokinase, hexokinase ii, hexokinase 2, hexokinase i, hk ii, hxk, liver glucokinase, hexokinase 1, hexokinase-2, hkdc1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ATP-D-hexose 6-phosphotransferase
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ATP-dependent hexokinase
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brain form hexokinase
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glucokinase
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glucose ATP phosphotransferase
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hexokinase
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hexokinase (phosphorylating)
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hexokinase D
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hexokinase PI
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hexokinase PII
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hexokinase type IV
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hexokinase type IV glucokinase
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hexokinase, tumor isozyme
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hexokinase-1
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hexokinase-10
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hexokinase-2
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hexokinase-4
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hexokinase-5
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hexokinase-6
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hexokinase-7
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hexokinase-8
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hexokinase-9
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HK
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HK4
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HXK
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HXK6
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HXK7
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HXK8
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HXK9
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kinase, hexo- (phosphorylating)
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muscle form hexokinase
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OsHXK
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
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SYSTEMATIC NAME
IUBMB Comments
ATP:D-hexose 6-phosphotransferase
D-Glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase.
CAS REGISTRY NUMBER
COMMENTARY hide
9001-51-8
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + D-allose
ADP + D-allose 6-phosphate
show the reaction diagram
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phosphorylation of D-allose at C6 by hexokinase is essential since it up-regulates expression of transcription factor OsABF1
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?
additional information
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
D-mannoheptulose
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
S177A
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D-allose activates AtABI5 expression in transgenic gin2 (mutant glucose-insensitive2-1 (gin2), which has a null mutation in the glucose sensor gene of AtHXK1) over-expressing wild-type AtHXK1 but not in gin2 over-expressing the catalytic mutant AtHXK1S177A, indicating that the D-allose phosphorylation by HXK to D-allose 6-phosphate (A6P) is the first step for the up-regulation of AtABI5 gene expression as well as D-allose-induced growth inhibition
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as GFP fusion protein in tobacco mesophyll protoplasts
expressed as GFP fusion protein in tobacco mesophyll protoplasts
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cho, J.I.; Ryoo, N.; Ko, S.; Lee, S.K.; Lee, J.; Jung, K.H.; Lee, Y.H.; Bhoo, S.H.; Winderickx, J.; An, G.; Hahn, T.R.; Jeon, J.S.
Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.)
Planta
224
598-611
2006
Oryza sativa, Oryza sativa (Q2KNB5), Oryza sativa (Q2KNB9), Oryza sativa (Q5W676), Oryza sativa (Q6Z398), Oryza sativa (Q8LH82)
Manually annotated by BRENDA team
Cheng, W.; Zhang, H.; Zhou, X.; Liu, H.; Liu, Y.; Li, J.; Han, S.; Wang, Y.
Subcellular localization of rice hexokinase (OsHXK) family members in the mesophyll protoplasts of tobacco
Biol. Plant.
55
173-177
2011
Oryza sativa, Oryza sativa (Q1WM16), Oryza sativa (Q2KNB4), Oryza sativa (Q2KNB5), Oryza sativa (Q2KNB7), Oryza sativa (Q2KNB9), Oryza sativa (Q5W676), Oryza sativa (Q6Z398), Oryza sativa (Q8LH82), Oryza sativa (Q8LQ68)
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Manually annotated by BRENDA team
Fukumoto, T.; Kano, A.; Ohtani, K.; Inoue, M.; Yoshihara, A.; Izumori, K.; Tajima, S.; Shigematsu, Y.; Tanaka, K.; Ohkouchi, T.; Ishida, Y.; Nishizawa, Y.; Tada, Y.; Ichimura, K.; Gomi, K.; Yoo, S.D.; Sheen, J.; Akimitsu, K.
Phosphorylation of D-allose by hexokinase involved in regulation of OsABF1 expression for growth inhibition in Oryza sativa L
Planta
237
1379-1391
2013
Arabidopsis thaliana, Oryza sativa
Manually annotated by BRENDA team