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Information on EC 2.6.1.76 - diaminobutyrate-2-oxoglutarate transaminase

for references in articles please use BRENDA:EC2.6.1.76

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IUBMB Comments

A pyridoxal-phosphate protein that requires potassium for activity . In the proteobacterium Acinetobacter baumannii, this enzyme is cotranscribed with the neighbouring ddc gene that also encodes EC 4.1.1.86, diaminobutyrate decarboxylase. Differs from EC 2.6.1.46, diaminobutyrate—pyruvate transaminase, which has pyruvate as the amino-group acceptor. This is the first enzyme in the ectoine-biosynthesis pathway, the other enzymes involved being EC 2.3.1.178, diaminobutyrate acetyltransferase and EC 4.2.1.108, ectoine synthase [3,4].

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
daba at, daba aminotransferase, l-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, diaminobutyrate transaminase, 2,4-diaminobutyrate aminotransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate
show the reaction diagram
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