Disease on EC 2.6.1.5 - tyrosine transaminase

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DISEASE
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Arthritis, Experimental
The influence of antagonists of poly(ADP-ribose)polymerase on the activity of antirheumatic drugs on the development of adjuvant arthritis in rats and on the induction of tyrosine aminotransferase in the liver of rats.
Asbestosis
Biochemical mechanisms in asbestos toxicity.
Brain Ischemia
Analysis of serum metabolites for the discovery of amino acid biomarkers and the effect of galangin on cerebral ischemia.
Carcinoma 256, Walker
Changes in liver tyrosine-alpha-ketoglutarate transaminase activity during growth of Walker carcinosarcoma 256.
Carcinoma, Hepatocellular
"Superinduction" of tyrosine aminotransferase by actinomycin D: a reevaluation.
"Superinduction" of tyrosine transaminase in hepatoma cell cultures: differential inhibition of synthesis and turnover by actionomycin D.
5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.
A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells.
A histochemical method for the demonstration of tyrosine aminotransferase in tissue culture cells, and studies of this enzyme in hepatoma tissue culture cells.
A new glucocorticoid receptor detected in host rat liver but not in various hepatomas.
A post-transcriptional site of induction of tyrosine aminotransferase by dexamethasone in Reuber H35 hepatoma cells.
Activity of protein kinase dependent on adenosine 3':5'-monophosphate and of its thermostable protein inhibitor in rat hepatoma (HTC) cells. Unlikely role in the permissive action of glucocorticoids.
Alteration of tyrosine aminotransferase activity in hepatoma cells in tissue culture by amphotericin B.
Amino acid transport in hepatoma cell cultures during tyrosine aminotransferase induction.
Analysis of insulin action using differentiated and dedifferentiated hepatoma cells.
Analysis of the induction and deinduction of tyrosine aminotransferase in enucleated HTC cells.
Analysis of the relation between receptor binding affinity and antagonist efficacy of antiglucocorticoids.
Antiglucocorticoid steroids have increased agonist activity in those hepatoma cell lines that are more sensitive to glucocorticoids.
Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain.
Aryl hydrocarcon hydroxylase and tyrosine aminotransferase activities in somatic-cell hybrids derived from hepatoma tissue culture HTC (rat) cells and 3T3 (mouse) benzo(a)pyrene-resistant cells.
Binding of glucocorticoid antagonists to androgen and glucocorticoid hormone receptors in rat skeletal muscle.
Cell-cycle regulation of insulin-stimulated tyrosine aminotransferase activity in rat hepatoma cells.
Chromosomal assignment and trans regulation of the tyrosine aminotransferase structural gene in hepatoma hybrid cells.
Concanavalin A alters the turnover rate of tyrosine aminotransferase in cultured hepatoma cells.
Constancy of expression of the protein kinase A regulatory subunit R1 alpha in hepatoma cell lines of different phenotypes.
Control of degradation and synthesis of induced tyrosine aminotransferase studied in hepatoma cells in culture.
Correlation between different gene expression assays designed to measure trans-activation potencies of systemic glucocorticoids.
Cyclic adenonosine monophosphate does not affect the stability of the messenger ribonucleic acid for tyrosine aminotransferase in cultured hepatoma cells.
Cytokines and the activity of tyrosine aminotransferase and superoxide dismutase in rat hepatoma cells in culture.
Description and analysis of differential sensitivity to glucocorticoids in Fao cells.
Dexamethasone phosphate-induced synthesis of tyrosine aminotransferase in hepatoma tissue culture cells. Studies of the early phases of induction and of the steroid requirement for maintanance of the induced rate of synthesis.
Differences in rates of tyrosine aminotransferase deinduction with cyclic AMP and glucocorticoids.
Differences in the mode of regulation of ornithine decarboxylase and tyrosine aminotransferase in H-35 rat hepatoma cells shown by varying the medium composition.
Differential activity of a tissue-specific extinguisher locus in hepatic and nonhepatic cells.
Differential effects of N-methyl-N'-nitro-N-nitrosoguanidine on constitutive and hormone-inducible gene expression in rat hepatoma cells.
Differential modulation of gene induction by glucocorticoids and antiglucocorticoids in rat hepatoma tissue culture cells.
Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes.
Differential sensitivity of HTC and Fu5-5 cells for induction of tyrosine aminotransferase by 3',5'-cyclic adenosine monophosphate.
Direct evidence that the protein kinase catalytic subunit mediates the effects of cAMP on tyrosine aminotransferase synthesis.
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.
Effect of B6 deficiency on hepatoma 7794A growth rate: activities of tyrosine transaminase and serine dehydratase before and after induction by hydrocortisone.
Effect of concanavalin A on tyrosine aminotransferase in rat hepatoma tissue culture cells. Rapid reversible inactivation of soluble enzyme.
Effect of cordycepin on induction of tyrosine aminotransferase employing hepatoma cells in tissue culture.
Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
Effect of phenobarbital on the glucocorticoid receptor in rat hepatoma cells.
Effect of potent antiglucocorticoids on dexamethasone induced enzymes in cultured hepatoma and rat liver cells.
Effect of pyridoxine deficiency on tyrosine transaminase activity and growth of four Morris hepatomas.
Effect of pyridoxine on the growth of Morris hepatoma No. 7288Ctc and enzyme activity.
Effects of 6- and 8-substituted analogs of adenosine 3':5'-monophosphate on phosphoenolpyruvate carboxykinase and tyrosine aminotransferase in hepatoma cell cultures.
Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas.
Effects of exogenous histones upon the induction of tryptophan pyrrolase and tyrosine transaminase in liver and Morris hepatomas.
Enzyme induction and receptor-binding affinity of steroidal 20-carboxamides in rat hepatoma tissue culture cells.
Epidermal growth factor inhibits phosphoenolpyruvate carboxykinase gene expression in rat hepatocytes in primary culture.
Establishment of a clonal strain of hepatoma cells derived from Morris hepatoma 8999.
Explanation for the apparent inactivation of tyrosine aminotransferase in hepatoma cells by concanavalin A.
Expression and amplification of cloned rat liver tyrosine aminotransferase in nonhepatic cells.
Expression of differentiated functions in hepatoma cell hybrids. I. Tyrosine aminotransferase in hepatoma-fibroblast hybrids.
Expression of differentiated functions in hepatoma cell hybrids: reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes.
Expression of hormonally induced tyrosine transaminase in normal, host liver and three Morris hepatomas.
Further evidence against post-transcriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
Further evidence for translational regulation of tyrosine aminotransferase synthesis by dibutyryl cyclic AMP in Reuber H35 hepatoma cells.
Genetic activity of a trans-regulatory locus in hepatoma hybrid cells.
Glucagon resistance of hepatoma cells. Evidence for receptor and post-receptor defects.
Glucocorticoid receptors in hepatocellular carcinoma and adjacent liver tissue.
Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.
Hormonal induction of tyrosine aminotransferase activity in host liver and hepatoma no. 7777 of normal and cofactor-depleted animals.
In vivo protein-DNA interactions in a glucocorticoid response element require the presence of the hormone.
Increased turnover of the messenger RNA encoding tyrosine aminotransferase can account for the desensitization and de-induction of tyrosine aminotransferase by 8-bromo-cyclic AMP treatment and removal.
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture.
Induction of tyrosine aminotransferase activity by concanavalin A in cultured rat hepatoma cells.
Induction of tyrosine aminotransferase and amino acid transport in Morris hepatomas and in adult and neonatal rat liver.
Induction of tyrosine aminotransferase and amino acid transport in rat hepatoma cells by insulin and the insulin-like growth factor, multiplication-stimulating activity. Mediation by insulin and multiplication-stimulating activity receptors.
Induction of tyrosine aminotransferase by D-glucosamine in rat hepatoma cell culture.
Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP employing hepatoma cells in tissue culture.
Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP in synchronized hepatoma cells.
Induction of tyrosine aminotransferase in H-35 hepatoma cells by cAMP captured in phospholipid vesicles.
Inhibition by ultraviolet irradiation of the glucocorticoid induction of tyrosine aminotransferase in bromodeoxyuridine-treated H-35 hepatoma.
Inhibition of steroid inducible tyrosine aminotransferase by mouse and rat interferon in hepatoma tissue culture cells.
Inhibition of steroid-inducible tyrosine aminotransferase gene expression by N-methyl-N'-nitro-N-nitrosoguanidine in a rat hepatoma cell line.
Inhibition of tyrosine aminotransferase induction by UTP deficiency and its reversal by 5-fluorouridine in cultured hepatoma cells.
Insulin induction of tyrosine aminotransferase in synchronized hepatoma cells.
Insulin-mediated inhibition of the induction of tyrosine aminotransferase by dexamethasone.
Insulin-mediated regulation of tyrosine aminotransferase in rat hepatoma cells: inhibition of transcription and inhibition of enzyme degradation.
Interaction of glucocorticoid hormones and cyclic nucleotides in induction of tyrosine aminotransferase in cultured hepatoma cells.
Interaction of trans-acting factors and re-expression of liver functions in hepatoma hybrid cells.
Interconversion of multiple forms of tyrosine aminotransferase in vitro and in vivo in cultured hepatoma cells.
Inverse correlation between cyclic GMP and tyrosine aminotransferase degradation in rat hepatoma tissue culture cells.
Inverse correlation between dexamethasone 21-mesylate agonist activity and sensitivity to dexamethasone for induction of tyrosine aminotransferase in rat hepatoma cells.
Ketoconazole inhibition and glucocorticoid action in the human lymphoblastic leukemia cell line CEM-C7.
Kinetics of steroid induction and deinduction of tyrosine aminotransferase synthesis in cultured hepatoma cells.
Lead may affect glucocorticoid signal transduction in cultured hepatoma cells through inhibition of protein kinase C.
Lectins mimic insulin in the induction of tyrosine aminotransferase.
Lipid peroxidation and activities of tyrosine aminotransferase and glutamine synthetase in hepatoma and glioma cells grown in bovine colostrum-supplemented medium.
Loss of reciprocal modulations of growth and liver function of hepatoma cells in culture by contact with cells or cell membranes.
Metabolism and antiproliferative effect of the glucocorticoid antagonist RU38486 in cultured liver and hepatoma cells.
Modulation of glucocorticoid induction of stably transfected tyrosine aminotransferase gene constructs involves elements up-stream of the glucocorticoid-responsive element.
Modulation of glucocorticoid induction of tyrosine aminotransferase gene expression by variations in cell density.
Modulation of hormonal induction of tyrosine aminotransferase and glucocorticoid receptors by aflatoxin B1 and sterigmatocystin in Reuber hepatoma cells.
Modulation of the agonist activity of antisteroids by a novel cis-acting element.
Modulation of transcription factor activity by a distant steroid modulatory element.
Naturally occurring and induced levels of amino acid transport and tyrosine aminotransferase in rats bearing Morris hepatomas.
New steroidal anti-inflammatory antedrugs: methyl 21-desoxy-21-chloro-11beta,17alpha-dihydroxy-3,20-dioxo-1, 4-pregnadiene-16alpha-carboxylate, methyl 21-desoxy-21-chloro-11beta-hydroxy-3,20-dioxo-1, 4-pregnadiene-16alpha-carboxylate, and their 9alpha-fluoro derivatives*.
Normal and stable transfected cancer cell lines: tools for a screening of progestogenic, antiprogestogenic and antiglucocorticoid substances.
Nucleus-dependent regulation of tyrosine aminotransferase degradation in hepatoma tissue culture cells.
On the steroid requirement for induction of tyrosine aminotransferase by N6, O2'-dibutyryl cyclic AMP in hepatoma cells.
Oncogene mediated repression of glucocorticoid hormone response elements and glucocorticoid receptor levels.
Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.
Physical properties, limited proteolysis, and acetylation of tyrosine aminotransferase from rat liver.
Positive and negative cAMP-mediated control of tyrosine aminotransferase synthesis in Reuber H35 hepatoma cells.
Preferential inhibition by 5-bromodeoxyuridine of the synthesis of tyrosine aminotransferase in hepatoma cell cultures.
Pretranslational control of tyrosine aminotransferase synthesis by 8-bromo-cyclic AMP in H-4 rat hepatoma cells.
Rat hepatoma cell variants resistant to insulin-diphtheria toxin A fragment conjugates. Genetic evidence for the separate pathways for insulin receptor-mediated mitogenic and hormonal stimulation.
Rat primary hepatocytes and H4 hepatoma cells display differential sensitivity to cyclic AMP at the level of expression of tyrosine aminotransferase.
Regulation of expression of tyrosine aminotransferase in somatic cell hybrids between rat hepatoma cells and mouse fibroblasts.
Regulation of gene expression in rat hepatocytes and hepatoma cells by insulin: quantitation of messenger ribonucleic acid's coding for tyrosine aminotransferase, tryptophan oxygenase, and phosphoenolpyruvate carboxykinase.
Regulation of hepatoma tissue culture cell tyrosine aminotransferase messenger ribonucleic acid by dexamethasone.
Regulation of insulin and insulin-like growth factor (IGF) responsiveness by IGFs in rat hepatoma cells.
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. 3. Comparative studies in H35, HTC, MH1C1 and RLC cells.
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. I. Effects of glucocorticoids, N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate and insulin in Reuber H35 cells.
Regulation of tyrosine aminotransferase by insulin in cultured rat hepatoma cells.
Regulation of tyrosine aminotransferase in rat liver. XI. Studies on the relationship of enzyme stability to enzyme turnover in cultured hepatoma cells.
Regulation of tyrosine aminotransferase synthesis in vitro by mRNA and soluble factors from hepatoma tissue culture cells.
Regulation of urea cycle enzymes in transplantable hepatomas and in the livers of tumor-bearing rats and humans.
Relations between steroid-cell contact, steroid-binding and induction of tyrosine aminotransferase.
Selective effect of the metallocarcinogen beryllium on hormonal regulation of gene expression in cultured cells.
Selective inhibition by sodium butyrate of glucocorticoid-induced tyrosine aminotransferase synthesis in hepatoma tissue-cultured cells.
Selectivity of interferon action: hormonal induction of tyrosine aminotransferase in rat hepatoma cells is much less sensitive to interferon than the replication of vesicular stomatitis virus or reovirus.
Somatic cell fusion in the study of glucocorticoid action.
Somatic cell hybrids between totipotent mouse teratocarcinoma and rat hepatoma cells.
Species-specific differences in the glucocorticoid receptor transactivation function upon binding with betamethasone-esters.
Stimulation of liver functions in hierarchical co-culture of bone marrow cells and hepatocytes.
Studies on the degradation of tyrosine aminotransferase in hepatoma cells in culture. Influence of the composition of the medium and adenosine triphosphate dependence.
Studies on the different molecular forms of tyrosine aminotransferase from rat liver and hepatoma cells.
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Synthesis and induction of tyrosine aminotransferase in synchronized hepatoma cells in culture.
Synthesis of a liver enzyme in hybrid cells.
Synthesis of inducible tyrosine aminotransferase in a cell-free extract from cultured hepatoma cells.
The acute effect of lead acetate on glucocorticoid regulation of tyrosine aminotransferase in hepatoma cells.
The distal enhancer implicated in the developmental regulation of the tyrosine aminotransferase gene is bound by liver-specific and ubiquitous factors.
The effects of metabolic inhibitors on the synthesis of inducible tyrosine aminotransferase in cultured hepatoma cells.
The induction, desensitization and de-induction of tyrosine aminotransferase by 8-bromo-cyclic AMP in rat hepatoma cells.
The influence of culture conditions on the induction of tyrosine aminotransferase by cyclic nucleotides in rat hepatoma cells.
The involvement of cyclic GMP in tyrosine aminotransferase degradation in rat hepatoma tissue culture cells.
The relationship between glucocorticoid binding and tyrosine aminotransferase induction in hepatoma tissue culture cells.
The role of messenger RNA in tyrosine aminotransferase superinduction: effects of camptothecin on hepatoma cells in culture.
The role of transcortin in glucocorticoid mediated enzyme induction: tyrosine aminotransferase induction in hepatoma tissue culture cells.
The stability of tyrosine aminotransferase and other proteins in enucleated rat hepatoma tissue culture cells.
The synergistic interaction of hydrocortisone and dibutyryl cyclic AMP during enzyme induction in hybrids between rat C6 glioma cells and FU5AH hepatoma cells.
Transcriptional and posttranscriptional regulation of tyrosine aminotransferase by insulin in rat hepatoma cells.
Transcriptional potencies of inhaled glucocorticoids.
Translation of tyrosine aminotransferase mRNA from hepatoma cells in a wheat germ cell-free system.
Transmembrane delivery of polypeptide hormones bypassing the intrinsic cell surface receptors: a conjugate of insulin with alpha 2-macroglobulin (alpha 2M) recognizing both insulin and alpha 2M receptors and its biological activity in relation to endocytic pathways.
Turnover of tyrosine transaminase in cultured hepatoma cells after inhibition of protein synthesis.
Tyrosine aminotransferase sensitivity to bromodeoxyuridine during restricted intervals of S phase in hepatoma cells.
Tyrosine transaminase induction: differential effect of 5-azacytidine on liver and hepatoma 5123D.
Variations in some molecular events during the early phases of the reuber H 35 hepatoma cell cycle. I. Glucocorticoid induction of tyrosine aminotransferase.
Variations in some molecular events during the early phases of the Reuber H35 cell cycle. IV-regulation of tyrosine aminotransferase.
Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells.
[Activation of transcription of the tyrosine aminotransferase gene in the rat McA-RN 7777 hepatoma cell line by cycloheximide]
[Criteria of the sensitivity of Zajdela and Morris hepatoma cells to glucocorticoids]
[Differences in expression and functional organization of the rat tyrosine aminotransferase gene in two lines of Morris hepatoma, 8994 and 7777]
[Effects of oxidative stress on the proliferation, differentiation and apoptosis in the human hepatoma cells]
[Hormonal induction of tyrosine aminotransferase and RNA synthesis in the cells of Morris hepatoma strain 7777]
[Regulation of the transcription of the tyrosine aminotransferase gene by glucocorticoids in Morris hepatoma 7777 and 8994 cells]
[Use of the tyrosine aminotransferase induction system for the demonstration of the signal effect of glucocorticoid hormones]
Carcinosarcoma
Changes in liver tyrosine-alpha-ketoglutarate transaminase activity during growth of Walker carcinosarcoma 256.
Chagas Disease
Trypanosoma cruzi: characterisation of the gene encoding tyrosine aminotransferase in benznidazole-resistant and susceptible populations.
Cholera
Cyclic AMP responses are suppressed in mammalian cells expressing the yeast low Km cAMP-phosphodiesterase gene.
Craniopharyngioma
Steroid hormone receptors in meningiomas of Chinese patients.
Cystinosis
Corneal dystrophies.
Darier Disease
Corneal dystrophies.
Diabetes Mellitus
Effects Mifepristone on Aminotransferase Activities in the Liver in Rats with Streptozotocin-Induced Diabetes Mellitus.
Diabetes Mellitus, Experimental
Modification of the pyridoxine-induction of tyrosine transaminase in rat liver by thyroid hormones and by alloxan diabetes.
[Activity and isoenzymes of tyrosine-alpha-ketoglutarate transaminase in the liver cytostructures of rats with alloxan diabetes. Effect of insulin]
Fabry Disease
Corneal dystrophies.
Glioma
Lipid peroxidation and activities of tyrosine aminotransferase and glutamine synthetase in hepatoma and glioma cells grown in bovine colostrum-supplemented medium.
The synergistic interaction of hydrocortisone and dibutyryl cyclic AMP during enzyme induction in hybrids between rat C6 glioma cells and FU5AH hepatoma cells.
Hemangioblastoma
Steroid hormone receptors in meningiomas of Chinese patients.
Hepatitis
Induction of tyrosine aminotransferase in galactosamine hepatitis.
Hyperglycemia
Insights into the mechanisms mediating hyperglycemic and stressogenic outcomes in rats treated with monocrotophos, an organophosphorus insecticide.
Resistance training restores metabolic alterations induced by monosodium glutamate in a sex-dependent manner in male and female rats.
Reversible hyperglycemia in rats following acute exposure to acephate, an organophosphorus insecticide: role of gluconeogenesis.
Hypokinesia
The effect of space flight on the board of the satellite Cosmos 2044 on plasma hormone levels and liver enzyme activities of rats.
Ichthyosis
Corneal dystrophies.
Infections
Diagnosis of chronic camel trypanosomosis by detection of the antibody of trypanosome tyrosine aminotransferase.
Diagnosis of trypanosomiasis in experimental mice and field-infected camels by detection of antibody to trypanosome tyrosine aminotransferase.
Effects of Schistosoma mansoni and Schistosoma japonicum infections on induction of hepatic tyrosine aminotransferase in mice.
Hormonal regulation of chimeric genes containing the phosphoenolpyruvate carboxykinase promoter regulatory region in hepatoma cells infected by murine retroviruses.
Increased excretion of aromatic amino acid catabolites in animals infected with Trypanosoma brucei evansi.
Phenylalanine metabolism in Microtus montanus chronically infected with Trypanosoma brucei gambiense.
The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43.
Intellectual Disability
Molecular biology and molecular pathology of a newly described molecular disease--tyrosinemia II (the Richner-Hanhart syndrome).
TAT gene mutation analysis in three Palestinian kindreds with oculocutaneous tyrosinaemia type II; characterization of a silent exonic transversion that causes complete missplicing by exon 11 skipping.
Tyrosinemia type II: Mutation update, 11 novel mutations and description of 5 independent subjects with a novel founder mutation.
Keratitis
Molecular biology and molecular pathology of a newly described molecular disease--tyrosinemia II (the Richner-Hanhart syndrome).
TAT gene mutation analysis in three Palestinian kindreds with oculocutaneous tyrosinaemia type II; characterization of a silent exonic transversion that causes complete missplicing by exon 11 skipping.
Keratoderma, Palmoplantar
Richner-Hanhart's syndrome: ultrastructural abnormalities of epidermal keratinization indicating a causal relationship to high intracellular tyrosine levels.
Lipidoses
Corneal dystrophies.
Liver Neoplasms
[The glucocorticoid receptors and the induction of tyrosine aminotransferase by glucocorticoid in the human liver cancer cell line (SMMC-7721) in vitro]
Liver Neoplasms, Experimental
Expression of hormonally induced tyrosine aminotransferase in host liver and Morris hepatoma No. 7777 during cofactor depletion.
Further studies on the induction of tyrosine aminotransferase in Morris hepatoma 9618A.
Loss of reciprocal modulations of growth and liver function of hepatoma cells in culture by contact with cells or cell membranes.
Messenger RNA activities for two liver enzymes, tyrosine aminotransferase and tryptophan oxygenase, in Morris hepatoma 5123C and 9618A and in HTC cells. Correlation with enzyme activities.
[Biochemical criteria of mammalian cell sensitivity to glucocorticoids]
[Criteria of the sensitivity of Zajdela and Morris hepatoma cells to glucocorticoids]
[Differences in expression and functional organization of the rat tyrosine aminotransferase gene in two lines of Morris hepatoma, 8994 and 7777]
[Hormonal induction of tyrosine aminotransferase and RNA synthesis in the cells of Morris hepatoma strain 7777]
[Regulation of the transcription of the tyrosine aminotransferase gene by glucocorticoids in Morris hepatoma 7777 and 8994 cells]
Lung Neoplasms
Analysis of co-factor function in a glucocorticoid-resistant small cell carcinoma cell line.
Lysosomal Storage Diseases
Corneal dystrophies.
Maple Syrup Urine Disease
The need of essential amino acids in children. An evaluation based on the intake of phenylalanine, tyrosine, leucine, isoleucine, and valine in children with phenylketonuria, tyrosine amino transferase defect, and maple syrup urine disease.
Melanoma
Tyrosine aminotransferase in AKR/J albino and C57BL/6J black mouse skin.
Meningioma
Progesterone and glucocorticoid receptor activation in meningiomas.
Steroid hormone receptors in meningiomas of Chinese patients.
Neoplasms
A glucocorticoid-resistant rat hepatoma cell variant contains functional glucocorticoid receptor.
Activity of the GR in G2 and mitosis.
Analysis of glucocorticoid-inducible genes in wild-type and variant rat hepatoma cells.
Apoptosis, redifferentiation and arresting proliferation simultaneously triggered by oxidative stress in human hepatoma cells.
Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene.
Chromatin structure of hormono-dependent promoters.
Control of -aminolevulinic acid synthetase and tyrosine aminotransferase in tumors and livers of tumor-bearing rats.
DNA regulatory elements for steroid hormones.
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Effect of pyridoxine on the growth of Morris hepatoma No. 7288Ctc and enzyme activity.
Effect of trenbolone acetate plus estradiol on transcriptional regulation of metabolism pathways in bovine liver.
Effects of an antitumoural rhodium complex on thioacetamide-induced liver tumor in rats. Changes in the activities of ornithine decarboxylase, tyrosine aminotransferase and of enzymes involved in fatty acid and glycerolipid synthesis.
Expressions of hepatic genes, especially IGF-binding protein-1, correlating with serum corticosterone in microarray analysis.
Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.
Induction of enzymes by glucagon, glucose repression, adenosine 3',5'-monophosphate concentration during carcinogenesis and in Morris 6918A hepatoma.
Induction of ornithine decarboxylase, tyrosine aminotransferase, and thymidine kinase by glucocorticoid in isolated, perfused liver after tumor inoculation.
Loss of reciprocal modulations of growth and liver function of hepatoma cells in culture by contact with cells or cell membranes.
Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription.
Phorbol ester inhibition of hormonal induction of tyrosine aminotransferase.
Phorbol myristate acetate (PMA) fails to prevent the appearance of markers associated with muscle and liver differentiation in culture.
Quantitative differences in androgen and glucocorticoid receptor DNA binding properties contribute to receptor-selective transcriptional regulation.
Selective activation of the probasin androgen-responsive region by steroid hormones.
The expressions of oncogenes and liver-specific genes in Morris hepatomas.
The mechanism for glucocorticoid-resistance in a rat hepatoma cell variant that contains functional glucocorticoid receptor.
The mechanism of cAMP-induced glucocorticoid receptor expression. Correlation to cellular glucocorticoid response.
Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells.
Transformation of cultured fetal rat liver cells by MDAB and phenobarbital. Morphological, biochemical and immunocytochemical characterization of cell lines.
Unlinked control of multiple glucocorticoid-induced processes in HTC cells.
Vitamin B6 metabolism in liver and liver-derived tumors.
[Different responses of DD/He and CC57BR/Mv mice to fasting]
[Effect of hepatocarcinogenicity of estragole on the glucocorticoid-mediated induction of liver-specific enzymes and the activity of the transcription factors FOXA and HNF4 in the liver of mouse and rat]
Neurologic Manifestations
Tyrosinemia type II: Mutation update, 11 novel mutations and description of 5 independent subjects with a novel founder mutation.
Osteosarcoma
Shift of circadian metabolic rhythm in BFO osteosarcoma-bearing mice.
Otitis
The in vivo glucocorticoid and antiglucocorticoid actions of medroxyprogesterone acetate.
Paraproteinemias
Corneal dystrophies.
Parasitemia
Diagnosis of trypanosomiasis in experimental mice and field-infected camels by detection of antibody to trypanosome tyrosine aminotransferase.
Phenylketonurias
The need of essential amino acids in children. An evaluation based on the intake of phenylalanine, tyrosine, leucine, isoleucine, and valine in children with phenylketonuria, tyrosine amino transferase defect, and maple syrup urine disease.
Photophobia
Tyrosinemia type II (Richner-Hanhart syndrome): A new mutation in the TAT gene.
Porphyrias
Glucose effect on tryptophan oxygenase and tyrosine aminotransferase induction after allylisopropylacetamide-induced porphyria in the rat.
Tryptophan pyrrolase, tryptophan and tyrosine transaminase changes during allylisopropylacetamide-induced porphyria in the rat.
Sarcoma
DNA regulatory elements for steroid hormones.
Sarcoma, Yoshida
Hormonal effect on tyrosine aminotransferase activities in Yoshida sarcoma and its variant lines.
Schistosomiasis japonica
Effects of Schistosoma mansoni and Schistosoma japonicum infections on induction of hepatic tyrosine aminotransferase in mice.
Sepsis
Endocrine influences on altered hepatic tyrosine transaminase activity during pneumococcal septicemia in the rat.
Skin Diseases
Corneal dystrophies.
Starvation
Changes in liver lobule glycogen zonation during prolonged fasting of rats previously fed a 30% casein diet and adapted to a controlled feeding schedule.
Correlation of circadian changes in tyrosine aminotransferase and tryptophan-2-3-dioxygenase in rat liver to irradiation at different times of the day.
Diurnal variations in response of rat liver tyrosine aminotransferase activity to food intake.
Effect of nutritional factors and cortisol on tyrosine aminotransferase activity in liver of brook trout, Salvelinus fontinalis Mitchill.
Loss of adaptive mechanisms during aging.
Regulation of hepatic tyrosine aminotransferase in genetically obese rats.
Serine dehydratase and tyrosine aminotransferase activities increased by long-term starvation and recovery by refeeding in rainbow trout (Oncorhynchus mykiss).
The influence of starvation and tryptophan administration on the metabolism of phenylalanine, tyrosine and tryptophan in isolated rat liver cells.
[The effect of prolonged starvation on changes in the activity of selected adaptive enzymes in rat liver]
Teratocarcinoma
Somatic cell hybrids between totipotent mouse teratocarcinoma and rat hepatoma cells.
Trypanosomiasis
Diagnosis of trypanosomiasis in experimental mice and field-infected camels by detection of antibody to trypanosome tyrosine aminotransferase.
Typhoid Fever
[The effect of lipids from typhoid endotoxin on the activity of some liver enzymes]
tyrosine transaminase deficiency
Corneal dystrophies.
Creatine and Pyruvate Prevent the Alterations Caused by Tyrosine on Parameters of Oxidative Stress and Enzyme Activities of Phosphoryltransfer Network in Cerebral Cortex of Wistar Rats.
Hereditary tyrosinaemia type II in a consanguineous Ashkenazi Jewish family: intrafamilial variation in phenotype; absence of parental phenotype effects on the fetus.
Herpetiform keratitis and palmoplantar hyperkeratosis: warning signs for Richner-Hanhart syndrome.
Response of the lysosomal system of the corneal epithelium to tyrosine-induced cell injury.
Richner-Hanhart syndrome (tyrosinemia type II). Case report and literature review.
Role of antioxidant treatment on DNA and lipid damage in the brain of rats subjected to a chemically induced chronic model of tyrosinemia type II.
Soluble tyrosine aminotransferase deficiency: an unusual cause of corneal ulcers.
The origin of urinary p-hydroxyphenylpyruvate in a patient with hepatic cytosol tyrosine aminotransferase deficiency.
Tyrosine aminotransferase deficiency in mink (Mustela vision): a model for human tyrosinemia II.
Tyrosinemias
A syndrome of hereditary tyrosinemia in mink (Mustela vison Schreb.).
Acute administration of l-tyrosine alters energetic metabolism of hippocampus and striatum of infant rats.
Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine.
Antioxidants Reverse the Changes in the Cholinergic System Caused by L-Tyrosine Administration in Rats.
Comparison of the tyrosine aminotransferase cDNA and genomic DNA sequences of normal mink and mink affected with tyrosinemia type II.
Corneal dystrophies.
Corneal lesion as the initial manifestation of tyrosinemia type II.
Creatine and Pyruvate Prevent the Alterations Caused by Tyrosine on Parameters of Oxidative Stress and Enzyme Activities of Phosphoryltransfer Network in Cerebral Cortex of Wistar Rats.
Defect in soluble tyrosine aminotransferase in skin fibroblasts of a patient with tyrosinemia.
Effect of acute administration of L-tyrosine on oxidative stress parameters in brain of young rats.
Enzyme defect in a case of tyrosinemia type I, acute form.
Hepatotoxin-induced hypertyrosinemia and its toxicological significance.
Hereditary tyrosinaemia type II in a consanguineous Ashkenazi Jewish family: intrafamilial variation in phenotype; absence of parental phenotype effects on the fetus.
Herpetiform keratitis and palmoplantar hyperkeratosis: warning signs for Richner-Hanhart syndrome.
Inherited and de novo deletion of the tyrosine aminotransferase gene locus at 16q22.1----q22.3 in a patient with tyrosinemia type II.
L-tyrosine induces DNA damage in brain and blood of rats.
Metabolic basis of hypertyrosinemia in liver disease.
New forms of hereditary tyrosinemia type II in mink: hepatic tyrosine aminotransferase defect.
Novel and recurrent tyrosine aminotransferase gene mutations in tyrosinemia type II.
Omega-3 fatty acid supplementation can prevent changes in mitochondrial energy metabolism and oxidative stress caused by chronic administration of L-tyrosine in the brain of rats.
Omega-3 fatty acid supplementation decreases DNA damage in brain of rats subjected to a chemically induced chronic model of Tyrosinemia type II.
Painful keratoderma and photophobia: hallmarks of tyrosinemia type II.
Persistent tyrosinemia associated with low activity of tyrosine aminotransferase.
Point mutations in the tyrosine aminotransferase gene in tyrosinemia type II.
Response of the lysosomal system of the corneal epithelium to tyrosine-induced cell injury.
Richner-Hanhart syndrome (tyrosinemia type II). Case report and literature review.
Richner-Hanhart syndrome (tyrosinemia type II): a case report of delayed diagnosis with pseudodendritic corneal lesion.
Richner-Hanhart syndrome: report of a case with a novel mutation of tyrosine aminotransferase.
Role of antioxidant treatment on DNA and lipid damage in the brain of rats subjected to a chemically induced chronic model of tyrosinemia type II.
Soluble and mitochondrial forms of tyrosine aminotransferase. Relationship to human tyrosinemia.
Soluble tyrosine aminotransferase deficiency: an unusual cause of corneal ulcers.
The effect of a low-protein diet and dietary supplementation of threonine on tyrosine and 2-(2-nitro-4-trifluoromethylbenzoyl) cyclohexane-1,3-dione-induced corneal lesions, the extent of tyrosinemia, and the activity of enzymes involved in tyrosine catabolism in the rat.
The genetic tyrosinemias.
The human tyrosine aminotransferase gene: characterization of restriction fragment length polymorphisms and haplotype analysis in a family with tyrosinemia type II.
The narrow substrate specificity of human tyrosine aminotransferase--the enzyme deficient in tyrosinemia type II.
The origin of urinary p-hydroxyphenylpyruvate in a patient with hepatic cytosol tyrosine aminotransferase deficiency.
Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)cyclohexane-1-3-dione (NTBC): effect on enzymes involved in tyrosine catabolism and relevance to ocular toxicity in the rat.
Tyrosine administration decreases glutathione and stimulates lipid and protein oxidation in rat cerebral cortex.
Tyrosine aminotransferase deficiency in mink (Mustela vision): a model for human tyrosinemia II.
Tyrosine impairs enzymes of energy metabolism in cerebral cortex of rats.
Tyrosinemia II: lessons in molecular pathophysiology.
Tyrosinemia type II (Richner-Hanhart syndrome): A new mutation in the TAT gene.
Tyrosinemia type II: Mutation update, 11 novel mutations and description of 5 independent subjects with a novel founder mutation.
Tyrosinemia type II: Novel mutations in TAT in a boy with unusual presentation.
[A case of tyrosinemia type II with convulsion and EEG abnormality]
[Oculo-cutaneous tyrosinosis (Richner-Hanhart syndrome). Histo-pathological study of a case]
[The metabolic basis of the hyperphenylalaninemias and tyrosinemia]
[Tyrosinemia type II. Case report]
Uremia
Translocation of inducible tyrosine aminotransferase to the mitochondrial fraction. Facilitation by acute uremia and other conditions.
Vesicular Stomatitis
Selectivity of interferon action: hormonal induction of tyrosine aminotransferase in rat hepatoma cells is much less sensitive to interferon than the replication of vesicular stomatitis virus or reovirus.
Vitamin B 12 Deficiency
Vitamin B12 deficiency results in the abnormal regulation of serine dehydratase and tyrosine aminotransferase activities correlated with impairment of the adenylyl cyclase system in rat liver.
Vitamin B 6 Deficiency
Effect of pyridoxine deficiency on tyrosine transaminase activity and growth of four Morris hepatomas.
Pyridoxal 5' phosphate involvement in age-related modifications of tyrosine aminotransferase: multiple form patterns.
Role of coenzyme in aminotransferase turnover.
The effect of pyridoxine deficiency on L-aromatic amino acid decarboxylase and tyrosine aminotransferase in developing brain.