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BRENDA support

Information on EC 2.6.1.22 - (S)-3-amino-2-methylpropionate transaminase

for references in articles please use BRENDA:EC2.6.1.22

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IUBMB Comments

Also acts on β-alanine and other ω-amino acids having carbon chains between 2 and 5. The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, (R)-3-amino-2-methylpropionate-pyruvate transaminase, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
aminotransferase, L-3-aminoisobutyrate, beta-aminobutyric transaminase, L-3-aminoisobutyrate transaminase, L-3-aminoisobutyric aminotransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links