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IUBMB Comments A pyridoxal-5'-phosphate protein. The enzyme from the bacterium Amycolatopsis orientalis catalyses the reaction in the reverse direction as part of the biosynthesis of the (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin.
The enzyme appears in viruses and cellular organisms
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HpgT
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(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate = 2-(3,5-dihydroxyphenyl)-2-oxoacetate + L-glutamate
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(S)-3,5-dihydroxyphenylglycine:2-oxoglutarate aminotransferase
A pyridoxal-5'-phosphate protein. The enzyme from the bacterium Amycolatopsis orientalis catalyses the reaction in the reverse direction as part of the biosynthesis of the (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin.
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(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin
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(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin
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(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
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(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
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(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin
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(3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine constituent of the glycopeptide antibiotic chloroeremomycin
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?
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pyridoxal 5'-phosphate
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a pyridoxal-phosphate protein
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brenda
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brenda
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physiological function
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine of the glycopeptide antibiotic chloroeremomycin
physiological function
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the enzyme is involved in the biosynthesis of (S)-3,5-dihydroxyphenylglycine of the glycopeptide antibiotic chloroeremomycin
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HPGT_AMYOR
438
0
47777
Swiss-Prot
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A0A7W7VLS0_9ACTN
439
0
47639
TrEMBL
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A0A7W7VDI9_9PSEU
434
0
47362
TrEMBL
-
A0A7W7PF15_STRNE
442
0
48296
TrEMBL
-
A0A7W8ANF4_STRST
444
0
47438
TrEMBL
-
A0A380SUS9_9PSED
438
0
47992
TrEMBL
-
A0A7W7SKE3_9ACTN
430
0
46616
TrEMBL
-
A0A498Q5Q4_9MYCO
420
0
44986
TrEMBL
-
A0A7X0N8Q0_9ACTN
447
0
47714
TrEMBL
-
A0A7X0IKQ3_9ACTN
439
0
48535
TrEMBL
-
A0A2P8AQV5_9ACTN
441
0
47824
TrEMBL
-
A0A7W7QFM9_9PSEU
473
0
51442
TrEMBL
-
A0A2P8AUL3_9ACTN
444
0
47547
TrEMBL
-
A0A7W9JAD4_9ACTN
427
0
46055
TrEMBL
-
A0A7W7C0B8_9ACTN
452
0
48694
TrEMBL
-
A0A2P7Z513_9ACTN
444
0
47955
TrEMBL
-
A0A7W9TJA0_9ACTN
435
0
47522
TrEMBL
-
A0A7W7R7S1_KITKI
441
0
47918
TrEMBL
-
A0A7W6L3M3_XANCA
438
0
47151
TrEMBL
-
A0A7W9IUK0_9ACTN
449
0
47770
TrEMBL
-
A0A2N8NUH1_STREU
440
0
47048
TrEMBL
-
A0A7W9JNJ6_9XANT
438
0
47141
TrEMBL
-
A0A7W4T338_9PSED
418
0
46408
TrEMBL
-
A0A7W8BHM9_STREU
450
0
47842
TrEMBL
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A0A7W7PXP9_9ACTN
447
0
47954
TrEMBL
-
A0A7W9I716_STRCU
446
0
48608
TrEMBL
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A0A7Y9WXX3_9ACTN
442
0
47445
TrEMBL
-
A0A7W6L4Y4_XANCA
448
0
48082
TrEMBL
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A0A7W7S673_9ACTN
426
0
45681
TrEMBL
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A0A7W7R9F6_KITKI
412
0
45464
TrEMBL
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A0A7W9N5I6_9XANT
448
0
48035
TrEMBL
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A0A7K0CC73_9ACTN
454
0
49019
TrEMBL
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A0A7W7VSF4_KITKI
435
0
47695
TrEMBL
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49800
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x * 49800, electrospray ionisation mass spectrometry
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x * 49800, electrospray ionisation mass spectrometry
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x * 49800, electrospray ionisation mass spectrometry
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expression of the N-terminal His6-tagged protein in Escherichia coli
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Sandercock, A.M.; Charles, E.H.; Scaife, W.; Kirkpatrick, P.N.; O’Brien, S.W.; Papageorgiou, E.A.; Spencer, J.B.; Williams, D.H.
Biosynthesis of the di-meta-hydroxyphenylglycine constituent of the vancomycin-group antibiotic chloroeremomycin
Chem. Commun. (Camb. )
2001
1252-12653
2001
Amycolatopsis orientalis, Amycolatopsis orientalis A82846
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brenda
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