Information on EC 2.5.1.99 - all-trans-phytoene synthase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.5.1.99
deleted. The activity was an artifact caused by photoisomerization of the product of EC 2.5.1.32, 15-cis-phytoene synthase.
RECOMMENDED NAME
GeneOntology No.
all-trans-phytoene synthase
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
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Z-phytoene, synthesized by the all-trans-phytoene synthase is prevalent in higher plants, fungi, algae, and photosynthetic bacteria, while E-phytoene, synthesized by EC 2.5.1.32, often predominates in nonphotosynthetic bacteria. Z-phytoene is the sole product of PSase in a phylogenetically diverse group of organisms, while a smaller subset of organisms have an analogous enzyme that appears to be specific for synthesis of the E isomer
metabolism
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phytoene synthase catalyzes the first pathway specific reaction in the carotenoid biosynthetic pathway and controls flux into the pathway
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