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Information on EC 2.5.1.90 - all-trans-octaprenyl-diphosphate synthase

for references in articles please use BRENDA:EC2.5.1.90

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IUBMB Comments

This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate, the isoprenoid side chain of ubiquinone-8 and menaquinone-8. The enzyme adds five isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
trans-prenyltransferase, octaprenyl diphosphate synthase, octaprenyl pyrophosphate synthase, octaprenyl pyrophosphate, opp synthetase, long-chain trans-prenyltransferase, long-chain c40 octaprenyl diphosphate synthase, gbs1789, octaprenyl-diphosphate synthase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate
show the reaction diagram
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