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Information on EC 2.5.1.128 - N4-bis(aminopropyl)spermidine synthase

for references in articles please use BRENDA:EC2.5.1.128
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IUBMB Comments
The enzyme, characterized from the thermophilic archaeon Thermococcus kodakarensis, synthesizes the branched-chain polyamine N4-bis(aminopropyl)spermidine, which is required for cell growth at high-temperature. When spermine is used as substrate, the enzyme forms N4-aminopropylspermine.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
BpsA, TK1691, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = 2 S-methyl-5'-thioadenosine + N4-bis(aminopropyl)spermidine
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S-adenosyl 3-(methylsulfanyl)propylamine + N4-aminopropylspermidine = S-methyl-5'-thioadenosine + N4-bis(aminopropyl)spermidine
show the reaction diagram
S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = S-methyl-5'-thioadenosine + N4-aminopropylspermidine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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